Results 1 - 10 of 5,056

et al. Gene expression patterns in human liver cancers

by Xin Chen, Siu Tim Cheung, Samuel So, Sheung Tat Fan, Christopher Barry, John Higgins, Kin-man Lai, Jiafu Ji, Rine Dudoit, Irene O. L. Ng, Matt Van De Rijn, David Botstein, Patrick O. Brown, Keith R. Yamamoto - Mol Biol Cell
"... Hepatocellular carcinoma (HCC) is a leading cause of death worldwide. Using cDNA microarrays to characterize patterns of gene expression in HCC, we found consistent differences between the expression patterns in HCC compared with those seen in nontumor liver tissues. The expression patterns in HCC w ..."
Abstract - Cited by 117 (4 self) - Add to MetaCart
different patients. Moreover, clonally related tumor masses that showed distinct expression profiles were also distinguished by genotypic differences. Some features of the gene expression patterns were associated with specific phenotypic and genotypic characteristics of the tumors, including growth rate

Coevolving High-Level Representations

by Peter J. Angeline, Jordan B. Pollack - TO APPEAR IN: ARTIFICIAL LIFE III
"... Several evolutionary simulations allow for a dynamic resizing of the genotype. This is an important alternative to constraining the genotype’s maximum size and complexity. In this paper, we add an additional dynamic to simulated evolution with the description of a genetic algorithm that coevolves it ..."
Abstract - Cited by 97 (13 self) - Add to MetaCart
its representation language with the genotypes. We introduce two mutation operators that permit the acquisition of modules from the genotypes during evolution. These modules form an increasingly highlevel representation language specific to the developmental environment. Experimental results

Continuity and discontinuity of behavioral inhibition and exuberance: Psychophysiological and behavioral influences across the first four years of life.

by Nathan A Fox , Heather A Henderson , Kenneth H Rubin , Susan D Calkins , Louis A Schmidt Fox , N Henderson , H Rubin , K Calkins , S D & Schmidt , L - Child Development, , 2001
"... Abstract: Four-month-old infants were screened (N = 433) for temperamental patterns thought to predict behavioral inhibition, including motor reactivity and the expression of negative affect. Those selected (N = 153) were assessed at multiple age points across the first 4 years of life for behavior ..."
Abstract - Cited by 124 (47 self) - Add to MetaCart
, ipsative) refer to homotypic continuity, which is continuity of similar behaviors or phenotypic attributes over time. The fifth, heterotypic continuity, refers to continuity of an inferred genotypic attribute presumed to underlie diverse phenotypic behaviors. It is this latter type of continuity

Toward an evolvable model of development for autonomous agent synthesis

by Frank Dellaert, All D. Beer , 1994
"... We are interested in the synthesis of autonomous agents using evolutionary techniques. Most work in this area utilizes a direct mapping from genotypic space to phenotypic space. In order to address some of the limitations of this approach, we present a simplified yet biologically defensible model of ..."
Abstract - Cited by 108 (3 self) - Add to MetaCart
We are interested in the synthesis of autonomous agents using evolutionary techniques. Most work in this area utilizes a direct mapping from genotypic space to phenotypic space. In order to address some of the limitations of this approach, we present a simplified yet biologically defensible model

CCR5 levels and expression pattern correlate with infectability by macrophage-tropic HIV-1

by Lijun Wu, William A. Paxton, Nasim Kassam, Nancy Ruffing, James B. Rottman, Nancy Sullivan, Hyeryun Choe, Joseph Sodroski, Walter Newman, Richard A. Koup, Charles R. Mackay , 1997
"... Chemokine receptors serve as coreceptors for HIV entry into CD4 � cells. Their expression is thought to determine the tropism of viral strains for different cell types, and also to influence susceptibility to infection and rates of disease progression. Of the chemokine receptors, CCR5 is the most im ..."
Abstract - Cited by 109 (9 self) - Add to MetaCart
important for viral transmission, since CCR5 is the principal receptor for primary, macrophage-tropic viruses, and individuals homozygous for a defective CCR5 allele (�32/ �32) are highly resistant to infection with HIV-1. In this study, CCR5-specific mAbs were generated using transfectants expressing high

The Advantages of Generative Grammatical Encodings for Physical Design

by Gregory S. Hornby, Jordan B. Pollack - In Congress on Evolutionary Computation , 2001
"... One of the applications of evolutionary algorithms is the automatic creation of designs. For evolutionary techniques to scale to the complexities necessary for actual engineering problems, it has been argued that generative systems, where the genotype is an algorithm for constructing the final desig ..."
Abstract - Cited by 107 (15 self) - Add to MetaCart
One of the applications of evolutionary algorithms is the automatic creation of designs. For evolutionary techniques to scale to the complexities necessary for actual engineering problems, it has been argued that generative systems, where the genotype is an algorithm for constructing the final

Development of a Genotype 325–Specific

by Bonno Bouma, Dirk Hendriks, Irène Juhan-vague, Paul J. Declerck, Ann Gils, Marie-christine Alessi, Els Brouwers, Miet Peeters, Pauline Marx, Judith Leurs, Ann Gils, Marie-christine Alessi, Els Brouwers, Miet Peeters, Pauline Marx, Judith Leurs, Bonno Bouma, Dirk Hendriks, Irène Juhan-vague, Paul J. Declerck , 2003
"... at: is onlineArteriosclerosis, Thrombosis, and Vascular Biology Information about subscribing to Subscriptions: ..."
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at: is onlineArteriosclerosis, Thrombosis, and Vascular Biology Information about subscribing to Subscriptions:

A first-generation linkage disequilibrium map of human chromosome 22

by E Dawson, G. R. Abecasis, S Bumpstead, Y Chen, S Hunt, D. M. Beare, J Pabial, E Tinsley, S Kirby, D Carter, M Papaspyridonos, S Livingstone, R Ganske, J Zernant, N Tõnisson, M Remm, R Mägi, T Puur, J Vilo, K Rice, P Deloukas, R Mott, A Metspalu, D. R. Bentley, L. R. Cardon - Nature , 2002
"... A collection of DNA sequence variants across the genome may be used to test specific genes or regions of the human genome for association with a variety of phenotypes such as disease risk or variable drug response. Detecting association relies on the non-random correlation (“linkage disequilibrium”, ..."
Abstract - Cited by 95 (7 self) - Add to MetaCart
A collection of DNA sequence variants across the genome may be used to test specific genes or regions of the human genome for association with a variety of phenotypes such as disease risk or variable drug response. Detecting association relies on the non-random correlation (“linkage disequilibrium

Genotyping Male-Specific RNA Coliphages by Hybridization with Oligonucleotide Probes

by F C Hsu, Y S Shieh, J Van Duin, M J Beekwilder, M D Sobsey, Fu-chih Hsu, Y. -s. Carol Shieh, J. Van Duin, M. J. Beekwilder, Mark, D. Sobsey - Applied & Environmental Microbiology , 1995
"... Genotyping male-specific RNA coliphages by ..."
Abstract - Cited by 16 (2 self) - Add to MetaCart
Genotyping male-specific RNA coliphages by

Culturing Selects for Specific Genotypes of Borrelia burgdorferi

by J. Clin Microbiol, W C Black Th, D E Norris, B J Johnson, J Piesman, G O Maupin, J L Clark, Douglas E. Norris, Barbara J. B. Johnson, Joseph Piesman, Gary O. Maupin, Jessica L. Clark, William C. Black Iv , 1997
"... Borrelia burgdorferi in an enzootic cycle in Culturing selects for specific genotypes of ..."
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Borrelia burgdorferi in an enzootic cycle in Culturing selects for specific genotypes of
Results 1 - 10 of 5,056