DMCA
Interference with testing for lysergic acid diethylamide
| Citations: | 4 - 0 self |
BibTeX
@MISC{Ritter_interferencewith,
author = {Detlef Ritter and Cherise M. Cortese and Linda C. Edwards and Judith L. Barr and Hyung D. Chung and Christopher Long},
title = {Interference with testing for lysergic acid diethylamide},
year = {}
}
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Abstract
We found a high rate (4.2%) of positive results for lysergic acid diethylamide (LSD) by Emit in 1898 urine samples that were submitted primarily from psychiatric patients for drugs-of-abuse (DOA) testing. Specimens that tested positive for LSD by Emit subsequently tested negative for LSD with two RIAs. Furthermore, LSD was not detected in randomly selected Emit-positive urine samples by gas chromatography–mass spectrometry. Normal urine samples tested positive for LSD by Emit when they were supplemented with therapeutic medi-cations that were prescribed for patients with positive urine LSD results by Emit. These therapeutic drugs interfered specifically with the Emit assay for LSD, since other Emit DOA tests were not affected by these medications at the tested concentrations.
