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Pr Glass Seeds for the Brachytherapy of Prostate Cancer. (2007)
BibTeX
@MISC{Jung07prglass,
author = {Jae Won Jung and Pr Glass Seeds and Won Jung and Leslie A. Braby and John Ford and Michael A. Walker and John W. Poston Sr and Jae Won Jung},
title = {Pr Glass Seeds for the Brachytherapy of Prostate Cancer.},
year = {2007}
}
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Abstract
A beta-emitting glass seed was proposed for the brachytherapy treatment of prostate cancer. Criteria for seed design were derived and several beta-emitting nuclides were examined for suitability. 142 Pr was selected as the isotope of choice. Seeds 0.08 cm in diameter and 0.9 cm long were manufactured for testing. The seeds were activated in the Texas A&M University research reactor. The activity produced was as expected when considering the meta-stable state and epi-thermal neutron flux. The MCNP5 Monte Carlo code was used to calculate the quantitative dosimetric parameters suggested in the American Association of Physicists in Medicine (AAPM) TG-43/60. The Monte Carlo calculation results were compared with those from a dose point kernel code. The dose profiles agree well with each other. The gamma dose of 142 Pr was evaluated. The gamma dose is 0.3 Gy at 1.0 cm with initial activity of 5.95 mCi and is insignificant to other organs. Measurements were performed to assess the 2-dimensional axial dose distributions using Gafchromic radiochromic film. The radiochromic film was calibrated using an X-ray machine calibrated against a National
Keyphrases
prostate cancer pr glass seed gamma dose epi-thermal neutron flux dose point kernel code monte carlo calculation result meta-stable state quantitative dosimetric parameter mcnp5 monte carlo code initial activity x-ray machine radiochromic film beta-emitting glass seed dose profile gafchromic radiochromic film seed design texas university research reactor 2-dimensional axial dose distribution brachytherapy treatment american association several beta-emitting nuclides
