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Automatic Detection of Gene Clusters by P-Quasi Complete Linkage Grouping
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BibTeX
@MISC{Fujibuchi_automaticdetection,
author = {Wataru Fujibuchi and Hiroyuki Ogata and Hideo Matsuda and Minoru Kanehisa},
title = {Automatic Detection of Gene Clusters by P-Quasi Complete Linkage Grouping},
year = {}
}
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Abstract
Introduction It is known that bacteria genomes are highly organized to express functions cooperatively, for instance, by operons or by locating related genes adjacently on the genome for the transcriptional advantage. Since the complete sequences of several genomes were released, the gene clusters that are defined as locally conserved gene sets beyond species have been progressively studied for these few years [1, 2, 3, 5]. However, it seems difficult to extract functionally important gene clusters manually because the detecting of gene clusters depends on which organisms to compare. Our goal is to extract significant gene clusters automatically with appropriate level of conservation among various species. In our system, tentatively called P-quasi completeness gene cluster detector, or P-CGC detector, the magnitude of significance of gene clusters can be controlled by P-% completeness of linkage of gene clusters, in other words, by the extent of conservation among various spec
Keyphrases
gene cluster automatic detection p-quasi complete linkage significant gene cluster transcriptional advantage appropriate level various specie gene set various spec complete sequence bacteria genome p-cgc detector p-quasi completeness gene cluster detector important gene cluster several genome
