@MISC{Aamodt_knowledge-intensivecase-based, author = {Agnar Aamodt}, title = {Knowledge-Intensive Case-Based Support for Automated Explanation of Biological Phenomena}, year = {} }
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Abstract
Abstract. The rapid growth of data stored in molecular biology-related databases has stimulated the development of integrative tools for retrieval and presentation of the data in the form of, e.g., biological association networks. We argue that a general and specific knowledge-based approach may provide substantial support for automated reconstruction of networks which otherwise tend to be large and, eventually, unreadable. This knowledge-based approach introduces a novel strategy with the potential to greatly enhance the explanatory power of automatically generated biological association networks. We discuss the motivation for a study of the process an expert employs while building a network, and suggest that a series of expert sessions be used as a case library for future reference. An example of a biological problem and the shape of its solution is described, and the types of knowledge involved are discussed. 1