BibTeX
@MISC{_conclusions,
author = {},
title = {Conclusions},
year = {}
}
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Abstract
54 male; 31.2 ±10.0 yrs) with no history of any psychopathology or neurological disorder. Novelty Oddball Task. An auditory novelty oddball task [5] consisted of eight 50-trial blocks of 300-ms tones (10 ms rise and fall time) and novel sounds (100-400 ms duration) presented in pseudorandom order (1000 ms SOA). Unique novel sounds (e.g., animals, instruments; p =.12) were intermixed with frequent nontargets (350 Hz; p =.76) and infrequent targets (500 Hz; p =.12) presented binaurally at 85 dB SPL. Subjects responded with a button press as quickly as possible when, and only when, they heard the infrequent target tone (response hand counterbalanced across blocks). ERP Recordings. As previously detailed [2], ERPs were recorded from 67 scalp sites (ActiView; BioSemi). Continuous EEG data were blink corrected using a spatial, singular value decomposition (NeuroScan). Stimulus-locked epochs (1200 ms, 200 ms prestimulus baseline) were extracted and screened for electrolyte bridges [7]. Channels containing artifacts or noise for any given trial were identified using a reference-free approach [8], and replaced by spherical spline interpolations [9] when possible. ERP averages were low-pass filtered at 12.5 Hz (-24 dB/octave) and baseline-corrected. CSD-tPCA for Novelty Oddball Task. Reference-free CSD waveforms (spherical spline Laplacian [9]) were computed from ERP averages to sharpen topographies, eliminate volume-conducted
Keyphrases
erp average novelty oddball task singular value decomposition auditory novelty oddball task db spl erp recording frequent nontargets fall time spherical spline laplacian m rise 100-400 m duration neurological disorder pseudorandom order infrequent target tone infrequent target response hand novel sound button press electrolyte bridge 50-trial block stimulus-locked epoch scalp site 300-ms tone m soa reference-free csd waveform continuous eeg data unique novel sound reference-free approach spherical spline interpolation
