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Functional magnetic resonance imaging evidence for a hierarchical organization of the prefrontal cortex (2007)
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BibTeX
@MISC{Badre07functionalmagnetic,
author = {David Badre},
title = {Functional magnetic resonance imaging evidence for a hierarchical organization of the prefrontal cortex},
year = {2007}
}
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Abstract
& The prefrontal cortex (PFC) is central to f lexible and or-ganized action. Recent theoretical and empirical results sug-gest that the rostro-caudal axis of the frontal lobes may ref lect a hierarchical organization of control. Here, we test whether the rostro-caudal axis of the PFC is organized hierarchically, based on the level of abstraction at which multiple represen-tations compete to guide selection of action. Four functional magnetic resonance imaging (fMRI) experiments parametri-cally manipulated the set of task-relevant (a) responses, (b) fea-tures, (c) dimensions, and (d) overlapping cue-to-dimension mappings. A systematic posterior to anterior gradient was evi-dent within the PFC depending on the manipulated level of representation. Furthermore, across four fMRI experiments, ac-tivation in PFC subregions was consistent with the sub- and superordinate relationships that define an abstract representa-tional hierarchy. In addition to providing further support for a representational hierarchy account of the rostro-caudal gra-dient in the PFC, these data provide important empirical con-straints on current theorizing about control hierarchies and the PFC. &
Keyphrases
prefrontal cortex hierarchical organization functional magnetic resonance imaging evidence rostro-caudal axis control hierarchy functional magnetic resonance imaging representational hierarchy account multiple represen-tations compete pfc subregions fmri experiment manipulated level important empirical con-straints frontal lobe systematic posterior cue-to-dimension mapping rostro-caudal gra-dient empirical result or-ganized action abstract representa-tional hierarchy
