BibTeX
@MISC{Linder_cellscience,
author = {Stefan Linder},
title = {Cell Science at a Glance 2079 Podosomes at a glance},
year = {}
}
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Abstract
Cells can contact the extracellular matrix (ECM) through a variety of specialized structures. These cell-matrix contacts contain membrane proteins such as integrins, which bind both matrix components and cellular proteins, thus bridging the substratum and the cytoskeleton (reviewed in Adams, 2001). Matrix contacts provide the physical linkage that enables cells to adhere to and migrate on (or through) the matrix. Moreover, they can also act as localized ‘relay stations ’ for important signaling pathways. Well-known cellmatrix contacts include focal complexes
