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722
Probabilistic Outputs for Support Vector Machines and Comparisons to Regularized Likelihood Methods
 ADVANCES IN LARGE MARGIN CLASSIFIERS
, 1999
"... The output of a classifier should be a calibrated posterior probability to enable postprocessing. Standard SVMs do not provide such probabilities. One method to create probabilities is to directly train a kernel classifier with a logit link function and a regularized maximum likelihood score. Howev ..."
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Cited by 1051 (0 self)
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The output of a classifier should be a calibrated posterior probability to enable postprocessing. Standard SVMs do not provide such probabilities. One method to create probabilities is to directly train a kernel classifier with a logit link function and a regularized maximum likelihood score. However, training with a maximum likelihood score will produce nonsparse kernel machines. Instead, we train an SVM, then train the parameters of an additional sigmoid function to map the SVM outputs into probabilities. This chapter compares classification error rate and likelihood scores for an SVM plus sigmoid versus a kernel method trained with a regularized likelihood error function. These methods are tested on three dataminingstyle data sets. The SVM+sigmoid yields probabilities of comparable quality to the regularized maximum likelihood kernel method, while still retaining the sparseness of the SVM.
Sparse Bayesian Learning and the Relevance Vector Machine
, 2001
"... This paper introduces a general Bayesian framework for obtaining sparse solutions to regression and classification tasks utilising models linear in the parameters. Although this framework is fully general, we illustrate our approach with a particular specialisation that we denote the `relevance vect ..."
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Cited by 966 (5 self)
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This paper introduces a general Bayesian framework for obtaining sparse solutions to regression and classification tasks utilising models linear in the parameters. Although this framework is fully general, we illustrate our approach with a particular specialisation that we denote the `relevance vector machine’ (RVM), a model of identical functional form to the popular and stateoftheart `support vector machine ’ (SVM). We demonstrate that by exploiting a probabilistic Bayesian learning framework, we can derive accurate prediction models which typically utilise dramatically fewer basis functions than a comparable SVM while offering a number of additional advantages. These include the benefits of probabilistic predictions, automatic estimation of `nuisance’ parameters, and the facility to utilise arbitrary basis functions (e.g. non`Mercer’ kernels). We detail the Bayesian framework and associated learning algorithm for the RVM, and give some illustrative examples of its application along with some comparative benchmarks. We offer some explanation for the exceptional degree of sparsity obtained, and discuss and demonstrate some of the advantageous features, and potential extensions, of Bayesian relevance learning.
A Bayesian Framework for the Analysis of Microarray Expression Data: Regularized tTest and Statistical Inferences of Gene Changes
 Bioinformatics
, 2001
"... Motivation: DNA microarrays are now capable of providing genomewide patterns of gene expression across many different conditions. The first level of analysis of these patterns requires determining whether observed differences in expression are significant or not. Current methods are unsatisfactory ..."
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Cited by 491 (6 self)
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Motivation: DNA microarrays are now capable of providing genomewide patterns of gene expression across many different conditions. The first level of analysis of these patterns requires determining whether observed differences in expression are significant or not. Current methods are unsatisfactory due to the lack of a systematic framework that can accommodate noise, variability, and low replication often typical of microarray data. Results: We develop a Bayesian probabilistic framework for microarray data analysis. At the simplest level, we model logexpression values by independent normal distributions, parameterized by corresponding means and variances with hierarchical prior distributions. We derive point estimates for both parameters and hyperparameters, and regularized expressions for the variance of each gene by combining the empirical variance with a local background variance associated with neighboring genes. An additional hyperparameter, inversely related to the number of empirical observations, determines the strength of the background variance. Simulations show that these point estimates, combined with a ttest, provide a systematic inference approach that compares favorably with simple ttest or fold methods, and partly compensate for the lack of replication. Availability: The approach is implemented in a software called CyberT accessible through a Web interface at www.genomics.uci.edu/software.html. The code is available as Open Source and is written in the freely available statistical language R. and Department of Biological Chemistry, College of Medicine, University of California, Irvine. To whom all correspondence should be addressed. Contact: pfbaldi@ics.uci.edu, tdlong@uci.edu. 1
Bayesian measures of model complexity and fit
 Journal of the Royal Statistical Society, Series B
, 2002
"... [Read before The Royal Statistical Society at a meeting organized by the Research ..."
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Cited by 466 (4 self)
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[Read before The Royal Statistical Society at a meeting organized by the Research
Bayesian Compressive Sensing
, 2007
"... The data of interest are assumed to be represented as Ndimensional real vectors, and these vectors are compressible in some linear basis B, implying that the signal can be reconstructed accurately using only a small number M ≪ N of basisfunction coefficients associated with B. Compressive sensing ..."
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Cited by 330 (24 self)
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The data of interest are assumed to be represented as Ndimensional real vectors, and these vectors are compressible in some linear basis B, implying that the signal can be reconstructed accurately using only a small number M ≪ N of basisfunction coefficients associated with B. Compressive sensing is a framework whereby one does not measure one of the aforementioned Ndimensional signals directly, but rather a set of related measurements, with the new measurements a linear combination of the original underlying Ndimensional signal. The number of required compressivesensing measurements is typically much smaller than N, offering the potential to simplify the sensing system. Let f denote the unknown underlying Ndimensional signal, and g a vector of compressivesensing measurements, then one may approximate f accurately by utilizing knowledge of the (underdetermined) linear relationship between f and g, in addition to knowledge of the fact that f is compressible in B. In this paper we employ a Bayesian formalism for estimating the underlying signal f based on compressivesensing measurements g. The proposed framework has the following properties: (i) in addition to estimating the underlying signal f, “error bars ” are also estimated, these giving a measure of confidence in the inverted signal; (ii) using knowledge of the error bars, a principled means is provided for determining when a sufficient
The Relevance Vector Machine
, 2000
"... The support vector machine (SVM) is a stateoftheart technique for regression and classification, combining excellent generalisation properties with a sparse kernel representation. However, it does suffer from a number of disadvantages, notably the absence of probabilistic outputs, the requirement ..."
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Cited by 294 (6 self)
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The support vector machine (SVM) is a stateoftheart technique for regression and classification, combining excellent generalisation properties with a sparse kernel representation. However, it does suffer from a number of disadvantages, notably the absence of probabilistic outputs, the requirement to estimate a tradeoff parameter and the need to utilise `Mercer' kernel functions. In this paper we introduce the Relevance Vector Machine (RVM), a Bayesian treatment of a generalised linear model of identical functional form to the SVM. The RVM suffers from none of the above disadvantages, and examples demonstrate that for comparable generalisation performance, the RVM requires dramatically fewer kernel functions.
Independent Factor Analysis
 Neural Computation
, 1999
"... We introduce the independent factor analysis (IFA) method for recovering independent hidden sources from their observed mixtures. IFA generalizes and unifies ordinary factor analysis (FA), principal component analysis (PCA), and independent component analysis (ICA), and can handle not only square no ..."
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Cited by 277 (9 self)
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We introduce the independent factor analysis (IFA) method for recovering independent hidden sources from their observed mixtures. IFA generalizes and unifies ordinary factor analysis (FA), principal component analysis (PCA), and independent component analysis (ICA), and can handle not only square noiseless mixing, but also the general case where the number of mixtures differs from the number of sources and the data are noisy. IFA is a twostep procedure. In the first step, the source densities, mixing matrix and noise covariance are estimated from the observed data by maximum likelihood. For this purpose we present an expectationmaximization (EM) algorithm, which performs unsupervised learning of an associated probabilistic model of the mixing situation. Each source in our model is described by a mixture of Gaussians, thus all the probabilistic calculations can be performed analytically. In the second step, the sources are reconstructed from the observed data by an optimal nonlinear ...
Extraction of HighResolution Frames from Video Sequences
 IEEE Transactions on Image Processing
, 1996
"... The human visual system appears to be capable of temporally integrating information in a video sequence in such a way that the perceived spatial resolution of a sequence appears much higher than the spatial resolution of an individual frame. While the mechanisms in the human visual system which do t ..."
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Cited by 264 (8 self)
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The human visual system appears to be capable of temporally integrating information in a video sequence in such a way that the perceived spatial resolution of a sequence appears much higher than the spatial resolution of an individual frame. While the mechanisms in the human visual system which do this are unknown, the effect is not too surprising given that temporally adjacent frames in a video sequence contain slightly different, but unique, information. This paper addresses how to utilize both the spatial and temporal information present in a short image sequence to create a single highresolution video frame. A novel observation model based on motion compensated subsampling is proposed for a video sequence. Since the reconstruction problem is illposed, Bayesian restoration with a discontinuitypreserving prior image model is used to extract a highresolution video still given a short lowresolution sequence. Estimates computed from a lowresolution image sequence containing a subp...
Assessment and Propagation of Model Uncertainty
, 1995
"... this paper I discuss a Bayesian approach to solving this problem that has long been available in principle but is only now becoming routinely feasible, by virtue of recent computational advances, and examine its implementation in examples that involve forecasting the price of oil and estimating the ..."
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Cited by 231 (0 self)
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this paper I discuss a Bayesian approach to solving this problem that has long been available in principle but is only now becoming routinely feasible, by virtue of recent computational advances, and examine its implementation in examples that involve forecasting the price of oil and estimating the chance of catastrophic failure of the U.S. Space Shuttle.