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Differential stability of Arabidopsis D-type cyclins: CYCD3;1 is a highly unstable protein degraded by a proteasome-dependent mechanism
- Plant J
, 2004
"... CYCD3;1 is a highly unstable protein degraded by a proteasome-dependent mechanism ..."
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Cited by 15 (2 self)
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CYCD3;1 is a highly unstable protein degraded by a proteasome-dependent mechanism
A novel motif in geminivirus replication proteins interacts with the plant retinoblastoma-related protein
- J Virol
, 2004
"... This article cites 67 articles, 27 of which can be accessed free at: ..."
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Cited by 12 (1 self)
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This article cites 67 articles, 27 of which can be accessed free at:
Role of an atypical E2F transcription factor in the control of Arabidopsis cell growth and differentiation
- Plant Cell
, 2004
"... The balance between cell proliferation and differentiation is crucial in multicellular organisms, where it is regulated by complex gene expression networks. This is particularly relevant in plants because organogenesis is a continuous postembryonic process. Here, we investigate the function of Arabi ..."
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Cited by 5 (3 self)
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The balance between cell proliferation and differentiation is crucial in multicellular organisms, where it is regulated by complex gene expression networks. This is particularly relevant in plants because organogenesis is a continuous postembryonic process. Here, we investigate the function of Arabidopsis thaliana E2Ff, an atypical member of the E2F family of transcription factors, which acts independently of a dimerization partner. We have focused our analysis on roots and hypocotyls, organs where (1) cell proliferation and differentiation are spatially and/or temporally separated, (2) growth depends on cell expansion in the longitudinal axis, and (3) the AtE2Ff promoter is active. AtE2Ff overexpression produced a reduction in the size of differentiated cells of these organs. Cells of mutant e2ff-1 plants with reduced levels of AtE2Ff mRNA were larger, especially in the hypocotyl, suggesting a role as a growth regulator. These effects of AtE2Ff are not associated with changes in nuclear ploidy levels or in the expression of cell cycle marker genes. However, expression of a subset of cell wall biogenesis genes is misregulated in an AtE2Ff-dependent manner, and based on chromatin immunoprecipitation experiments, they seem to be direct E2F targets. Our results highlight the complex regulatory function exerted by E2F and suggest a possible role of AtE2Ff in repressing cell wall biosynthesis genes during cell elongation in differentiated cells.
SCFSKP2B- AND KPC1-DEPENDENT DEGRADATION OF CYCLIN- DEPENDENT KINASE INHIBITOR KRP1 AND CELL CYCLE REGULATION IN ARABIDOPSIS THALIANA
, 2005
"... iii This dissertation is dedicated to Jingrong Wang, my wife, and Sifa Ren and Demei Zhao, my parents, for their love and support. iv Acknowledgements In the past seven and a half years of my graduate school life, it has been a wonderful and unforgettable journey. I was trained in two laboratories a ..."
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iii This dissertation is dedicated to Jingrong Wang, my wife, and Sifa Ren and Demei Zhao, my parents, for their love and support. iv Acknowledgements In the past seven and a half years of my graduate school life, it has been a wonderful and unforgettable journey. I was trained in two laboratories and at two universities. I studied for four years at the University of Texas (UT) at Austin and for three and a half years at IU-Bloomington. First of all, I would like to thank my advisor, Mark Estelle. I first met Mark in 2000 when I was a student in his Plant Developmental Genetics class at UT-Austin. From his class, I learned the power of genetics to studying plant development, which attracted me to switch to Mark’s lab to pursue my Ph.D. I feel truly lucky to have an advisor like Mark and to work in such a great laboratory. In the past five and a half years, under Mark’s guidance, I have
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"... The development of multicellular organisms requires mechanisms that pattern cell proliferation and cell differentiation with temporal and spatial precision. The requirement of such patterning strategies is, for example, evident in plant root meristems, where stem cells ..."
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The development of multicellular organisms requires mechanisms that pattern cell proliferation and cell differentiation with temporal and spatial precision. The requirement of such patterning strategies is, for example, evident in plant root meristems, where stem cells
unknown title
"... Progression through the cell cycle is essential for the continued existence of all uni- and multicellular organisms. It is crucial for the survival of a cell that its DNA is correctly replicated. In mammals, the onset of DNA replication is regulated by the ..."
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Progression through the cell cycle is essential for the continued existence of all uni- and multicellular organisms. It is crucial for the survival of a cell that its DNA is correctly replicated. In mammals, the onset of DNA replication is regulated by the
unknown title
, 2005
"... E2F targets and the two ORC1 genes are differently expressed in proliferating and endoreplicating cells ..."
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E2F targets and the two ORC1 genes are differently expressed in proliferating and endoreplicating cells
unknown title
, 2005
"... E2F targets and the two ORC1 genes are differently expressed in proliferating and endoreplicating cells ..."
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E2F targets and the two ORC1 genes are differently expressed in proliferating and endoreplicating cells
