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Individuals with depressive symptoms typically show deficits in decision-making. However, most work has emphasized decision-making under gain-maximization conditions. A gainmaximization framework may undermine decision-making when depressive symptoms are present because depressives are generally more sensitive to losses than gains. The present study examined decision making in a non-clinical sample of depressive and non-depressive individuals under gain-maximization or loss-minimization conditions using a task for which the currently available rewards depend upon participants ’ previous history of choices. As predicted, we found a cross over interaction whereby depressive individuals were superior to non-depressive individuals under loss-minimization conditions, but were inferior to non-depressive individuals under gain-maximization conditions. In addition, we found that loss-minimization performance was superior to gain-maximization performance for depressive individuals, but that gainmaximization performance was superior to loss-minimization performance for non-depressive individuals. These results suggest that decision making deficits observed when depressive symptoms are present may be attenuated when decisions involve minimizing losses rather than maximizing gains.

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