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...n lowdensity cultures.sThese could include members of the cathepsin proteases (245)sfamily or serine proteases like urokinase, which have been shown to be activatedsduring wound healing in the cornea =-=(246)-=-.sAs one of the functions of theskeratocytes in-situ is to remodel the ECM, it is possible that the proteolytic actionsof these cells is part of the keratocyte phenotype.sIncreased degradation, as asr...

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...in the HOSCC cell lines highlights that thesuPAR has a connection to the actin cytoskeleton in these cell lines. This is particularlysimportant for cell-ECM adhesion events that are mediated by uPAR (=-=Bernstein et al., 2004-=-;sAbu-Ali et al., 2005).sFor instance, the uPAR mediated adhesion of adenoid cystic carcinomascell lines on collagen type I induced the co-localization of uPAR with actin associatedsmolecules such as ...