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Authors Abdullah Pandor Research Fellow, ScHARR
, 2005
"... The use of oxaliplatin and capecitabine for the adjuvant treatment of colon cancer ..."
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The use of oxaliplatin and capecitabine for the adjuvant treatment of colon cancer
INDEX WORDS: Flavonoids, Quercetin, SW-480, Glutathione-S-Transferase,
, 2003
"... (Under the Direction of JAMES L. HARGROVE) Many cases of colon cancer, the third leading site of cancer in the United States, are diet-related. Fruit and vegetable intake is inversely associated with colon cancer risk, and the flavonoids may have an important role. One mechanism by which flavonoids, ..."
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(Under the Direction of JAMES L. HARGROVE) Many cases of colon cancer, the third leading site of cancer in the United States, are diet-related. Fruit and vegetable intake is inversely associated with colon cancer risk, and the flavonoids may have an important role. One mechanism by which flavonoids, including quercetin, may prevent colon cancer is the regulation of Phase 1 and Phase 2 enzymes, which protect the body from foreign substances. Quercetin, the most abundant flavonoid, has been described as a monofunctional enzyme inducer, which is optimal for cancer prevention. This study tested the effect of quercetin on Cytochrome P450 1A1, Glutathione S-transferase, and Quinone reductase activity, and cell viability and proliferation in the SW-480 cell line. Quinone reductase activity decreased significantly with the highest concentration of quercetin. There was no significant effect on the other enzyme activities, cell viability or proliferation. The results of this study cannot confirm that quercetin acts as a monofunctional enzyme inducer.
A study of individual food groups
, 2014
"... This thesis must be used in accordance with the provisions of the Copyright Act 1968. Reproduction of material protected by copyright may be an infringement of copyright and copyright owners may be entitled to take legal action against persons who infringe their copyright. Section 51 (2) of the Copy ..."
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This thesis must be used in accordance with the provisions of the Copyright Act 1968. Reproduction of material protected by copyright may be an infringement of copyright and copyright owners may be entitled to take legal action against persons who infringe their copyright. Section 51 (2) of the Copyright Act permits an authorized officer of a university library or archives to provide a copy (by communication or otherwise) of an unpublished thesis kept in the library or archives, to a person who satisfies the authorized officer that he or she requires the reproduction for the purposes of research or study. The Copyright Act grants the creator of a work a number of moral rights, specifically the right of attribution, the right against false attribution and the right of integrity. You may infringe the author’s moral rights if you:- fail to acknowledge the author of this thesis if you quote sections from the work- attribute this thesis to another author- subject this thesis to derogatory treatment which may prejudice the author’s reputation For further information contact the University’s
