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9,661
The irreducibility of the space of curves of given genus
- Publ. Math. IHES
, 1969
"... Fix an algebraically closed field k. Let Mg be the moduli space of curves of genus g over k. The main result of this note is that Mg is irreducible for every k. Of course, whether or not M s is irreducible depends only on the characteristic of k. When the characteristic s o, we can assume that k ~- ..."
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Cited by 506 (2 self)
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from char. o to char. p provided that p> 2g q-i. Unfortunately, attempts to extend this method to all p seem to get stuck on difficult questions of wild ramification. Nowadays, the Teichmtiller theory gives a thoroughly analytic but very profound insight into this irreducibility when k----C. Our
Mosaic analysis with a repressible cell marker for studies of gene function in neuronal morphogenesis.
- Neuron
, 1999
"... We have modified an FLP/FRT-based genetic mosaic system to label either neurons derived from a common progenitor or isolated single neurons, in the Drosophila CNS. These uniquely labeled neurons can also be made homozygous for a mutation of interest within an otherwise phenotypically wild-type brai ..."
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Cited by 455 (22 self)
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We have modified an FLP/FRT-based genetic mosaic system to label either neurons derived from a common progenitor or isolated single neurons, in the Drosophila CNS. These uniquely labeled neurons can also be made homozygous for a mutation of interest within an otherwise phenotypically wild
Big Omega Versus the Wild Functions*
"... The question of the desirable properties and proper definitions of the Order-of-Magnitude symbols, in particular 0 and e, is addressed once more. The definitions proposed are chosen for complementary mathemati-cal properties, rather than for similarity of form. L brmoDuCTioN The old order changeth, ..."
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The question of the desirable properties and proper definitions of the Order-of-Magnitude symbols, in particular 0 and e, is addressed once more. The definitions proposed are chosen for complementary mathemati-cal properties, rather than for similarity of form. L brmoDuCTioN The old order changeth, yielding place to new, And God Urals himself in many ways, Lest owe good custom should corrupt thc world-Tennyson, The 14 Ih i f t h e K i n g. The issue of the proper definitions for the Order-of-Magnitude symbols would appear to have been settled once and for all by Knuth in 111. At the end of an exhaustive discussion the subject is, the author feels, about "beaten to death". The purpose of this communica-tion is to point out that there is life in the old dog yeti ' The dehlerations below Were prompted by surprise that, while proving a lower bound where the precise definitions mat-tered, matters % P ere n o t a s d e a r c u t a s o n e m i g h t a s s u m e t h
Induction of mutant dynamin specifically blocks endocytic coated vesicle formation
- J. Cell
, 1994
"... Abstract. Dynarnin is the mammalian homologue to the Drosophila shibire gene product. Mutations in this 100-kD GTPase cause a pleiotropic defect in endocytosis. To further investigate its role, we generated stable HeLa cell lines expressing either wild-type dynamin or a mutant defective in GTP bindi ..."
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Cited by 242 (6 self)
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Abstract. Dynarnin is the mammalian homologue to the Drosophila shibire gene product. Mutations in this 100-kD GTPase cause a pleiotropic defect in endocytosis. To further investigate its role, we generated stable HeLa cell lines expressing either wild-type dynamin or a mutant defective in GTP
A Comparative Anatomy of Credit-Risk Models
- Journal of Banking and Finance
"... Within the past two years, important advances have been made in modeling credit risk at the portfolio level. Practitioners and policy makers have invested in implementing and exploring a variety of new models individually. Less progress has been made, however, with comparative analyses. Direct compa ..."
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Cited by 227 (9 self)
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CreditRisk +.Weshow that, despite differences on the surface, the underlying mathematical structures are similar. The structural parallels provide intuition for the relationship between the two models and allow us to describe quite precisely where the models differ in functional form, distributional
Double muscling in cattle due to mutations in the myostatin gene
- Proc. Natl Acad. Sci. USA
, 1997
"... ABSTRACT Myostatin (GDF-8) is a member of the transforming growth factor  superfamily of secreted growth and differentiation factors that is essential for proper regulation of skeletal muscle mass in mice. Here we report the myostatin sequences of nine other vertebrate species and the identificati ..."
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Cited by 216 (4 self)
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in phenotypes of double-muscled cattle and myostatin null mice suggests that myostatin performs the same biological function in these two species and is a potentially useful target for genetic manipulation in other farm animals. The transforming growth factor  superfamily encompasses a large group of secreted
The topology of the regulatory interactions predicts the expression pattern of the segment polarity genes in Drosophila melanogaster
, 2003
"... Expression of the Drosophila segment polarity genes is initiated by a prepattern of pair-rule gene products and maintained by a network of regulatory interactions throughout several stages of embryonic development. Analysis of a model of gene interactions based on differential equations showed tha ..."
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Cited by 186 (11 self)
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by the topology of the network and whether components are present or absent, rather than the absolute levels of the mRNAs and proteins and the functional details of their interactions. The model is able to reproduce the wild type gene expression patterns, as well as the ectopic expression patterns observed
Behavioral theories and the neurophysiology of reward,
- Annu. Rev. Psychol.
, 2006
"... ■ Abstract The functions of rewards are based primarily on their effects on behavior and are less directly governed by the physics and chemistry of input events as in sensory systems. Therefore, the investigation of neural mechanisms underlying reward functions requires behavioral theories that can ..."
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Cited by 187 (0 self)
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91 Although these theories provide important insights into reward function, they tend to neglect the fact that individuals usually operate in a world with limited nutritional and mating resources, and that most resources occur with different degrees of uncertainty. The animal in the wild
Learning to detect and classify malicious executables in the wild
- Journal of Machine Learning Research
, 2006
"... We describe the use of machine learning and data mining to detect and classify malicious executables as they appear in the wild. We gathered 1,971 benign and 1,651 malicious executables and encoded each as a training example using n-grams of byte codes as features. Such processing resulted in more t ..."
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Cited by 90 (1 self)
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We describe the use of machine learning and data mining to detect and classify malicious executables as they appear in the wild. We gathered 1,971 benign and 1,651 malicious executables and encoded each as a training example using n-grams of byte codes as features. Such processing resulted in more
Results 1 - 10
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9,661