Results 1 - 10 of 53,102

Stretch-activated whole cell currents in adult rat cardiac myocytes

by Tao Zeng, Glenna C. L. Bett, Frederick Sachs, Glenna C. L. Bett, Frederick Sachs - Am J Physiol Heart Circ Physiol 278: H548–H557 , 2000
"... Stretch-activated whole cell currents in adult rat cardiac ..."
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Stretch-activated whole cell currents in adult rat cardiac

Whole cell currents and mechanical responses of isolated outer hair cells.

by J Santos-Sacchi , J P Dilger - Hear. Res. , 1988
"... Outer hair cells (OHCs) exhibit electrically induced cell movements which are considered to enhance the frequency selectivity and sensitivity of basilar membrane vibration. Using simultaneous whole cell voltage clamp and video analysis. we demonstrate that the mechanical response of OHCs is not alt ..."
Abstract - Cited by 19 (3 self) - Add to MetaCart
Outer hair cells (OHCs) exhibit electrically induced cell movements which are considered to enhance the frequency selectivity and sensitivity of basilar membrane vibration. Using simultaneous whole cell voltage clamp and video analysis. we demonstrate that the mechanical response of OHCs

Stomatin Inhibits Pannexin-1-Mediated Whole-Cell Currents by Interacting with Its Carboxyl Terminal

by Haiying Zhan, Craig S. Moore, Bojun Chen, Xin Zhou, Xin-ming Ma, Kumiko Ijichi, Michael V. L. Bennett, Xue-jun Li, Stephen J. Crocker, Zhao-wen Wang , 2011
"... The pannexin-1 (Panx1) channel (often referred to as the Panx1 hemichannel) is a large-conductance channel in the plasma membrane of many mammalian cells. While opening of the channel is potentially detrimental to the cell, little is known about how it is regulated under physiological conditions. He ..."
Abstract - Cited by 2 (0 self) - Add to MetaCart
. Here we show that stomatin inhibited Panx1 channel activity. In transfected HEK-293 cells, stomatin reduced Panx1-mediated whole-cell currents without altering either the total or membrane surface Panx1 protein expression. Stomatin coimmunoprecipitated with full-length Panx1 as well as a Panx1 fragment

Role of Inducible Nitric-Oxide Synthase in Regulation of Whole-Cell Current in Lung Epithelial Cells1

by Beata Kamosinska, Anna Radomski, Shu Fu, Paul Man, Marek W. Radomski, Marek Duszyk
"... Lung inflammation is associated with enhanced expression of proinflammatory cytokines and increased production of nitric oxide (NO) by inducible NO synthase (iNOS). To investigate the possible relationship between cytokine-induced expression of iNOS and epithelial ion channel function, we measured w ..."
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whole-cell current in A549 cells treated with a mixture of cytokines: tumor necrosis factor, interleukin-1b, and interferon-g for 12 h. Cytokines significantly increased the expression and activity of iNOS, and reduced generation of cGMP in response to stimu-lation with NO donor S

Sodium-Alanine Cotransport in Renal Proximal Tubule Cells Investigated by Whole-Cell Current Recording

by Joachim Hoyer, Heinz Gogelein
"... ABSTRACT Sodium-alanine cotransport was investigated in single isolated proximal tubule cells from rabbit kidney with the whole-cell current recording technique. Addition of L-alanine at the extracellular side induced an inward-directed sodium current and a cell depolarization. The sodium-alanine co ..."
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ABSTRACT Sodium-alanine cotransport was investigated in single isolated proximal tubule cells from rabbit kidney with the whole-cell current recording technique. Addition of L-alanine at the extracellular side induced an inward-directed sodium current and a cell depolarization. The sodium

Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation

by Yael Gavrieli, Yoav Sherman, Shmuel A. Ben-sasson - J. Cell , 1992
"... Abstract. Programmed cell death (PCD) plays a key role in developmental biology and in maintenance of the steady state in continuously renewing tissues. Currently, its existence is inferred mainly from gel electrophoresis of a pooled DNA extract as PCD was shown to be associated with DNA fragmentati ..."
Abstract - Cited by 691 (0 self) - Add to MetaCart
Abstract. Programmed cell death (PCD) plays a key role in developmental biology and in maintenance of the steady state in continuously renewing tissues. Currently, its existence is inferred mainly from gel electrophoresis of a pooled DNA extract as PCD was shown to be associated with DNA

Ptolemy: A Framework for Simulating and Prototyping Heterogeneous Systems

by Joseph Buck, Soonhoi Ha, Edward A. Lee, David G. Messerschmitt , 1992
"... Ptolemy is an environment for simulation and prototyping of heterogeneous systems. It uses modern object-oriented software technology (C++) to model each subsystem in a natural and efficient manner, and to integrate these subsystems into a whole. Ptolemy encompasses practically all aspects of design ..."
Abstract - Cited by 571 (89 self) - Add to MetaCart
Ptolemy is an environment for simulation and prototyping of heterogeneous systems. It uses modern object-oriented software technology (C++) to model each subsystem in a natural and efficient manner, and to integrate these subsystems into a whole. Ptolemy encompasses practically all aspects

The Visual Analysis of Human Movement: A Survey

by D. M. Gavrila - Computer Vision and Image Understanding , 1999
"... The ability to recognize humans and their activities by vision is key for a machine to interact intelligently and effortlessly with a human-inhabited environment. Because of many potentially important applications, “looking at people ” is currently one of the most active application domains in compu ..."
Abstract - Cited by 743 (9 self) - Add to MetaCart
The ability to recognize humans and their activities by vision is key for a machine to interact intelligently and effortlessly with a human-inhabited environment. Because of many potentially important applications, “looking at people ” is currently one of the most active application domains

The Generative Lexicon

by James Pustejovsky - Computational Linguistics , 1991
"... this paper, I will discuss four major topics relating to current research in lexical semantics: methodology, descriptive coverage, adequacy of the representation, and the computational usefulness of representations. In addressing these issues, I will discuss what I think are some of the central prob ..."
Abstract - Cited by 1341 (45 self) - Add to MetaCart
this paper, I will discuss four major topics relating to current research in lexical semantics: methodology, descriptive coverage, adequacy of the representation, and the computational usefulness of representations. In addressing these issues, I will discuss what I think are some of the central

The spandrels of San Marco and the Panglossian paradigm: a critique of the adaptationist programme.

by S J Gould , R C Lewontin - Proceedings of the Royal Society of London Series B, Biological Sciences , 1979
"... An adaptationist programme has dominated evolutionary thought in England and the United States during the past 40 years. It is based on faith in the power of natural selection as an optimizing agent. It proceeds by breaking an organism into unitary 'traits' and proposing an adaptive story ..."
Abstract - Cited by 538 (2 self) - Add to MetaCart
) that organisms must be analysed as integrated wholes, with Bauplane so constrained by phyletic heritage, pathways of development and general architecture that the constraints themselves become more interesting and more important in delimiting pathways of change than the selective force that may mediate change
Results 1 - 10 of 53,102