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FLAVOENZYMES HAVE THE unique abil-

by unknown authors , 2000
"... ity to catalyse a wide range of biochemi-cal reactions. They are involved in the dehydrogenation of a variety of metabo-lites, in one- and two-electron transfer from and to redox centres, in light emission, in the activation of oxygen for oxidation and hydroxylation reactions1. Because of the extrao ..."
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ity to catalyse a wide range of biochemi-cal reactions. They are involved in the dehydrogenation of a variety of metabo-lites, in one- and two-electron transfer from and to redox centres, in light emission, in the activation of oxygen for oxidation and hydroxylation reactions1. Because of the extraordinary spectro-scopic properties of the flavin cofactor, flavoproteins are perfectly suited to detailed enzymological studies1. As a result, they have emerged as one of the best-studied enzyme families. Our understanding of flavin chem-istry has been augmented in the recent

The role of deliberate practice in the acquisition of expert performance

by K. Anders Ericsson, Ralf Th. Krampe, Clemens Tesch-romer - Psychological Review , 1993
"... The theoretical framework presented in this article explains expert performance as the end result of individuals ' prolonged efforts to improve performance while negotiating motivational and external constraints. In most domains of expertise, individuals begin in their childhood a regimen of ef ..."
Abstract - Cited by 690 (15 self) - Add to MetaCart
for a minimum of 10 years. Analysis of expert performance provides unique evidence on the potential and limits of extreme environmental adaptation and learning. Our civilization has always recognized exceptional individuals, whose performance in sports, the arts, and science is vastly superior

Pastry: Scalable, decentralized object location and routing for large-scale peer-to-peer systems

by Antony Rowstron , Peter Druschel - IN PROC. OF THE 18TH IFIP/ACM INTERNATIONAL CONFERENCE ON DISTRIBUTED SYSTEMS PLATFORMS, , 2001
"... This paper presents the design and evaluation of Pastry, a scalable, distributed object location and routing substrate for wide-area peer-to-peer applications. Pastry performs application-level routing and object location in a potentially very large overlay network of nodes connected via the Intern ..."
Abstract - Cited by 1932 (1 self) - Add to MetaCart
the Internet. It can be used to support a variety of peer-to-peer applications, including global data storage, data sharing, group communication and naming. Each node in the Pastry network has a unique identifier (nodeId). When presented with a message and a key, a Pastry node efficiently routes the message

IN THIS ISSUE The Naval Postgraduate School’s Unique Ability for Classified

by unknown authors , 2003
"... The Naval Postgraduate School’s primary mission is graduate education. As in any graduate level institution, research is a vital component of the education process. At NPS, the student body is composed mainly of active duty officers from the military services–Navy, Marine Corps, Air Force and Army. ..."
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. Coupled with upper level graduate courses with an emphasis on DoN/DoD problems are the experience of these officers and unique facilities that allow research up to the Secret Compartmented Information (SCI) level. These assets allow for a dynamic “classified research environment. ” This article contains

A Virtual Machine Introspection Based Architecture for Intrusion Detection

by Tal Garfinkel, Mendel Rosenblum - In Proc. Network and Distributed Systems Security Symposium , 2003
"... Today's architectures for intrusion detection force the IDS designer to make a difficult choice. If the IDS resides on the host, it has an excellent view of what is happening in that host's software, but is highly susceptible to attack. On the other hand, if the IDS resides in the network, ..."
Abstract - Cited by 423 (5 self) - Add to MetaCart
this through the use of a virtual machine monitor. Using this approach allows us to isolate the IDS from the monitored host but still retain excellent visibility into the host's state. The VMM also offers us the unique ability to completely mediate interactions between the host software and the underlying

Origins of the Modern Mind: Three Stages in the Evolution of Culture and Cognition

by Merlin Donald , 1991
"... This book was an attempt to synthesize various sources of information--neurobiological, psychological, archeological and anthropological, among others--about our cognitive origins, in the belief that the human mind co-evolved in close interaction with both brain and culture. I should make clear from ..."
Abstract - Cited by 337 (0 self) - Add to MetaCart
from the start that I have no illusions about my ability to become expert in all of the disciplines touched on by this enterprise; accordingly my effort should be regarded with suspicion by all; at best, it will probably prove to be no more than a guide to some of the important questions that remain

A System for Induction of Oblique Decision Trees

by Sreerama K. Murthy, Simon Kasif, Steven Salzberg - Journal of Artificial Intelligence Research , 1994
"... This article describes a new system for induction of oblique decision trees. This system, OC1, combines deterministic hill-climbing with two forms of randomization to find a good oblique split (in the form of a hyperplane) at each node of a decision tree. Oblique decision tree methods are tuned espe ..."
Abstract - Cited by 292 (14 self) - Add to MetaCart
especially for domains in which the attributes are numeric, although they can be adapted to symbolic or mixed symbolic/numeric attributes. We present extensive empirical studies, using both real and artificial data, that analyze OC1's ability to construct oblique trees that are smaller and more accurate

unique

by unknown authors
"... strengths, ingenious solutions 2005: Another Year of Record Results Net sales: $21.2 billion, up 5.8% Operating income: $5.0 billion, up 9.4% Net income: $3.2 billion, up 7.0% Earnings per share: $4.12, up 9.9% Dividends per share: $1.68, up 16.7% A Global, Diversified Technology Company 3M is funda ..."
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is fundamentally a science-based company. We produce thousands of imaginative products, and we’re a leader in scores of markets – from health care and highway safety to office products and optical films for LCD displays. Our success begins with our ability to apply our technologies – often in combination

Multiplexed protein quantitation in Saccharomyces cerevisiae using aminereactive isobaric tagging reagents,”

by Philip L Ross , Yulin N Huang , Jason N Marchese , Brian Williamson , Kenneth Parker , Stephen Hattan , Nikita Khainovski , Sasi Pillai , Subhakar Dey , Scott Daniels , Subhasish Purkayastha , Peter Juhasz , Stephen Martin , Michael Bartlet-Jones , Feng He ¶ Allan Jacobson , Darryl J Pappin - Molecular and Cellular Proteomics, , 2004
"... We describe here a multiplexed protein quantitation strategy that provides relative and absolute measurements of proteins in complex mixtures. At the core of this methodology is a multiplexed set of isobaric reagents that yield amine-derivatized peptides. The derivatized peptides are indistinguisha ..."
Abstract - Cited by 248 (1 self) - Add to MetaCart
as well as unique effects on protein expression. Molecular & Cellular Proteomics 3:1154 -1169, 2004. An initial step in the systematic investigation of cellular processes is the identification and measurement of expression levels of relevant sets of proteins. Recently, quantitative approaches

Probabilistic Independent Component Analysis

by Christian F. Beckmann, Christian F. Beckmann*t, Stephen M. Smith , 2003
"... Independent Component Analysis is becoming a popular exploratory method for analysing complex data such as that from FMRI experiments. The application of such 'model-free' methods, however, has been somewhat restricted both by the view that results can be uninterpretable and by the lack of ..."
Abstract - Cited by 208 (13 self) - Add to MetaCart
of ability to quantify statistical significance. We present an integrated approach to Probabilistic ICA for FMRI data that allows for non-square mixing in the presence of Gaussian noise. We employ an objective estimation of the amount of Gaussian noise through Bayesian analysis of the true dimensionality
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