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Analysis of relative gene expression data using real-time quantitative

by Kenneth J. Livak, Thomas D. Schmittgen - PCR and 2 ���CT method. Methods 25 , 2001
"... of the target gene relative to some reference group The two most commonly used methods to analyze data from real-time, quantitative PCR experiments are absolute quantifica-such as an untreated control or a sample at time zero tion and relative quantification. Absolute quantification deter- in a time ..."
Abstract - Cited by 2666 (6 self) - Add to MetaCart
of the target gene relative to some reference group The two most commonly used methods to analyze data from real-time, quantitative PCR experiments are absolute quantifica-such as an untreated control or a sample at time zero tion and relative quantification. Absolute quantification deter- in a

Data Integration: A Theoretical Perspective

by Maurizio Lenzerini - Symposium on Principles of Database Systems , 2002
"... Data integration is the problem of combining data residing at different sources, and providing the user with a unified view of these data. The problem of designing data integration systems is important in current real world applications, and is characterized by a number of issues that are interestin ..."
Abstract - Cited by 965 (45 self) - Add to MetaCart
Data integration is the problem of combining data residing at different sources, and providing the user with a unified view of these data. The problem of designing data integration systems is important in current real world applications, and is characterized by a number of issues

Power-law distributions in empirical data

by Aaron Clauset, Cosma Rohilla Shalizi, M. E. J. Newman - ISSN 00361445. doi: 10.1137/ 070710111. URL http://dx.doi.org/10.1137/070710111 , 2009
"... Power-law distributions occur in many situations of scientific interest and have significant consequences for our understanding of natural and man-made phenomena. Unfortunately, the empirical detection and characterization of power laws is made difficult by the large fluctuations that occur in the t ..."
Abstract - Cited by 607 (7 self) - Add to MetaCart
demonstrate these methods by applying them to twentyfour real-world data sets from a range of different disciplines. Each of the data sets has been conjectured previously to follow a power-law distribution. In some cases we find these conjectures to be consistent with the data while in others the power law

Bigtable: A distributed storage system for structured data

by Fay Chang, Jeffrey Dean, Sanjay Ghemawat, Wilson C. Hsieh, Deborah A. Wallach, Mike Burrows, Tushar Chandra, Andrew Fikes, Robert E. Gruber - IN PROCEEDINGS OF THE 7TH CONFERENCE ON USENIX SYMPOSIUM ON OPERATING SYSTEMS DESIGN AND IMPLEMENTATION - VOLUME 7 , 2006
"... Bigtable is a distributed storage system for managing structured data that is designed to scale to a very large size: petabytes of data across thousands of commodity servers. Many projects at Google store data in Bigtable, including web indexing, Google Earth, and Google Finance. These applications ..."
Abstract - Cited by 1028 (4 self) - Add to MetaCart
place very different demands on Bigtable, both in terms of data size (from URLs to web pages to satellite imagery) and latency requirements (from backend bulk processing to real-time data serving). Despite these varied demands, Bigtable has successfully provided a flexible, high-performance solution

From Data Mining to Knowledge Discovery in Databases.

by Usama Fayyad , Gregory Piatetsky-Shapiro , Padhraic Smyth - AI Magazine, , 1996
"... ■ Data mining and knowledge discovery in databases have been attracting a significant amount of research, industry, and media attention of late. What is all the excitement about? This article provides an overview of this emerging field, clarifying how data mining and knowledge discovery in database ..."
Abstract - Cited by 538 (0 self) - Add to MetaCart
in databases are related both to each other and to related fields, such as machine learning, statistics, and databases. The article mentions particular real-world applications, specific data-mining techniques, challenges involved in real-world applications of knowledge discovery, and current and future

Clustering by passing messages between data points

by Brendan J. Frey, Delbert Dueck - Science , 2007
"... Clustering data by identifying a subset of representative examples is important for processing sensory signals and detecting patterns in data. Such “exemplars ” can be found by randomly choosing an initial subset of data points and then iteratively refining it, but this works well only if that initi ..."
Abstract - Cited by 696 (8 self) - Add to MetaCart
if that initial choice is close to a good solution. We devised a method called “affinity propagation,” which takes as input measures of similarity between pairs of data points. Real-valued messages are exchanged between data points until a high-quality set of exemplars and corresponding clusters gradually emerges

A new mathematical model for relative quantification in real-time RT-PCR. Nucleic Acids Res

by Michaelw. Pfaffl
"... Use of the real-time polymerase chain reaction (PCR) to amplify cDNA products reverse transcribed from mRNA is on the way to becoming a routine tool in molecular biology to study low abundance gene expression. Real-time PCR is easy to perform, provides the necessary accuracy and produces reliable as ..."
Abstract - Cited by 1088 (4 self) - Add to MetaCart
as well as rapid quantification results. But accurate quantification of nucleic acids requires a reproducible methodology and an adequate mathematical model for data analysis. This study enters into the particular topics of the relative quantification in real-time RT–PCR of a target gene transcript

Combining labeled and unlabeled data with co-training

by Avrim Blum, Tom Mitchell , 1998
"... We consider the problem of using a large unlabeled sample to boost performance of a learning algorithm when only a small set of labeled examples is available. In particular, we consider a setting in which the description of each example can be partitioned into two distinct views, motivated by the ta ..."
Abstract - Cited by 1633 (28 self) - Add to MetaCart
provide empirical results on real web-page data indicating that this use of unlabeled examples can lead to signi cant improvement of hypotheses in practice. As part of our analysis, we provide new re-

Calibrating noise to sensitivity in private data analysis

by Cynthia Dwork, Frank Mcsherry, Kobbi Nissim, Adam Smith - In Proceedings of the 3rd Theory of Cryptography Conference , 2006
"... Abstract. We continue a line of research initiated in [10, 11] on privacypreserving statistical databases. Consider a trusted server that holds a database of sensitive information. Given a query function f mapping databases to reals, the so-called true answer is the result of applying f to the datab ..."
Abstract - Cited by 649 (60 self) - Add to MetaCart
Abstract. We continue a line of research initiated in [10, 11] on privacypreserving statistical databases. Consider a trusted server that holds a database of sensitive information. Given a query function f mapping databases to reals, the so-called true answer is the result of applying f

The Entity-Relationship Model: Toward a Unified View of Data

by Peter Pin-shan Chen - ACM Transactions on Database Systems , 1976
"... A data model, called the entity-relationship model, is proposed. This model incorporates some of the important semantic information about the real world. A special diagrammatic technique is introduced as a tool for database design. An example of database design and description using the model and th ..."
Abstract - Cited by 1829 (6 self) - Add to MetaCart
A data model, called the entity-relationship model, is proposed. This model incorporates some of the important semantic information about the real world. A special diagrammatic technique is introduced as a tool for database design. An example of database design and description using the model
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