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Tissue Classification with Gene Expression Profiles

by Amir Ben-Dor, Laurakay Bruhn, Agilent Laboratories, Nir Friedman, Miche`l Schummer, Iftach Nachman, U. Washington, U. Washington, Zohar Yakhini - Journal of Computational Biology , 2000
"... Constantly improving gene expression profiling technologies are expected to provide understanding and insight into cancer related cellular processes. Gene expression data is also expected to significantly aid in the development of efficient cancer diagnosis and classification platforms. In this work ..."
Abstract - Cited by 240 (11 self) - Add to MetaCart
Constantly improving gene expression profiling technologies are expected to provide understanding and insight into cancer related cellular processes. Gene expression data is also expected to significantly aid in the development of efficient cancer diagnosis and classification platforms

Support Vector Machine Classification and Validation of Cancer Tissue Samples Using Microarray Expression Data

by Terrence S. Furey, Nello Cristianini, Nigel Duffy, David W. Bednarski, Michèl Schummer, David Haussler , 2000
"... Motivation: DNA microarray experiments generating thousands of gene expression measurements, are being used to gather information from tissue and cell samples regarding gene expression differences that will be useful in diagnosing disease. We have developed a new method to analyse this kind of data ..."
Abstract - Cited by 569 (1 self) - Add to MetaCart
using support vector machines (SVMs). This analysis consists of both classification of the tissue samples, and an exploration of the data for mis-labeled or questionable tissue results. Results: We demonstrate the method in detail on samples consisting of ovarian cancer tissues, normal ovarian tissues

Automated model-based tissue classification of MR images of the brain

by Koen Van Leemput, Frederik Maes, Dirk Vandermeulen, Paul Suetens , 1999
"... We describe a fully automated method for model-based tissue classification of Magnetic Resonance (MR) images of the brain. The method interleaves classification with estimation of the model parameters, improving the classification at each iteration. The algorithm is able to segment single- and multi ..."
Abstract - Cited by 214 (14 self) - Add to MetaCart
We describe a fully automated method for model-based tissue classification of Magnetic Resonance (MR) images of the brain. The method interleaves classification with estimation of the model parameters, improving the classification at each iteration. The algorithm is able to segment single

Gene selection for cancer classification using support vector machines

by Isabelle Guyon, Jason Weston, Stephen Barnhill, Vladimir Vapnik, Nello Cristianini - Machine Learning
"... Abstract. DNA micro-arrays now permit scientists to screen thousands of genes simultaneously and determine whether those genes are active, hyperactive or silent in normal or cancerous tissue. Because these new micro-array devices generate bewildering amounts of raw data, new analytical methods must ..."
Abstract - Cited by 1115 (24 self) - Add to MetaCart
Abstract. DNA micro-arrays now permit scientists to screen thousands of genes simultaneously and determine whether those genes are active, hyperactive or silent in normal or cancerous tissue. Because these new micro-array devices generate bewildering amounts of raw data, new analytical methods must

Feature selection based on mutual information: Criteria of max-dependency, max-relevance, and min-redundancy

by Hanchuan Peng, Fuhui Long, Chris Ding - IEEE TRANS. PATTERN ANALYSIS AND MACHINE INTELLIGENCE , 2005
"... Feature selection is an important problem for pattern classification systems. We study how to select good features according to the maximal statistical dependency criterion based on mutual information. Because of the difficulty in directly implementing the maximal dependency condition, we first der ..."
Abstract - Cited by 571 (8 self) - Add to MetaCart
cancer cell lines, and lymphoma tissues). The results confirm that mRMR leads to promising improvement on feature selection and classification accuracy.

es, L s Tissue classification

by Rician Distribution
"... inee ..."
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Abstract not found

selection and tissue classification

by Minghe Sun, Momiao Xiong
"... mathematical programming approach for gene ..."
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mathematical programming approach for gene

for Unsupervised, MRI Brain-Tissue Classification

by Suyash P. Awate Tolga Tasdizen, Suyash P. Awate A, Ross T. Whitaker A , 2006
"... This paper presents a novel method for brain-tissue classification in magnetic resonance (MR) images that relies on a very general, adaptive statistical model of image neighborhoods. The method models MR-tissue intensities as derived from stationary random fields. It models the associated higher-ord ..."
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This paper presents a novel method for brain-tissue classification in magnetic resonance (MR) images that relies on a very general, adaptive statistical model of image neighborhoods. The method models MR-tissue intensities as derived from stationary random fields. It models the associated higher

Robust unsupervised tissue classification in mr image

by Dzung L. Pham - in Proceedings of the IEEE International Symposium on Biomedical Imaging , 2004
"... A general framework for performing robust, unsupervised tissue classification in magnetic resonance images is presented. Tissue classification is formulated as an estimation problem based on an imaging model. Prior models are used within the estimation problem to compensate for noise and intensity i ..."
Abstract - Cited by 2 (1 self) - Add to MetaCart
A general framework for performing robust, unsupervised tissue classification in magnetic resonance images is presented. Tissue classification is formulated as an estimation problem based on an imaging model. Prior models are used within the estimation problem to compensate for noise and intensity

A comparative study of feature selection and multiclass classification methods for tissue classification based on gene expression

by Tao Li, Chengliang Zhang, Mitsunori Ogihara - Bioinformatics , 2004
"... This paper studies the problem of building multiclass classifiers for tissue classification based on gene expression. The recent development of microarray technologies has enabled biologists to quantify gene expression of tens of thousands of genes in a single experiment. Biologists have begun colle ..."
Abstract - Cited by 143 (5 self) - Add to MetaCart
This paper studies the problem of building multiclass classifiers for tissue classification based on gene expression. The recent development of microarray technologies has enabled biologists to quantify gene expression of tens of thousands of genes in a single experiment. Biologists have begun
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