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Comparison of discrimination methods for the classification of tumors using gene expression data

by Sandrine Dudoit, Jane Fridlyand, Terence P. Speed - JOURNAL OF THE AMERICAN STATISTICAL ASSOCIATION , 2002
"... A reliable and precise classification of tumors is essential for successful diagnosis and treatment of cancer. cDNA microarrays and high-density oligonucleotide chips are novel biotechnologies increasingly used in cancer research. By allowing the monitoring of expression levels in cells for thousand ..."
Abstract - Cited by 770 (6 self) - Add to MetaCart
A reliable and precise classification of tumors is essential for successful diagnosis and treatment of cancer. cDNA microarrays and high-density oligonucleotide chips are novel biotechnologies increasingly used in cancer research. By allowing the monitoring of expression levels in cells

Motivation through the Design of Work: Test of a Theory. Organizational Behavior and Human Performance,

by ] Richard Hackman , Grec R Oldham , 1976
"... A model is proposed that specifies the conditions under which individuals will become internally motivated to perform effectively on their jobs. The model focuses on the interaction among three classes of variables: (a) the psychological states of employees that must be present for internally motiv ..."
Abstract - Cited by 622 (2 self) - Add to MetaCart
in seven organizations, and results support its validity. A number of special features of the model are discussed (including its use as a basis for the diagnosis of jobs and the evaluation of job redesign projects), and the model is compared to other theories of job design. Work redesign is becoming

the review on

by Manoj Kumar Pandey, Æ Reena Rani, Æ Suraksha Agrawal, Immunotherapy Æ Immunoglobulin (ivig - D0 −D0 Mixing” in this Review
"... Abstract Recurrent spontaneous abortion (RSA) is de-fined as three or more consecutive pregnancy losses prior to the 20th week of gestation. The etiology of recurrent spontaneous abortion is often unclear and may be multifactorial, with much controversy regarding diag-nosis and treatment. Reasonably ..."
Abstract - Cited by 361 (4 self) - Add to MetaCart
Abstract Recurrent spontaneous abortion (RSA) is de-fined as three or more consecutive pregnancy losses prior to the 20th week of gestation. The etiology of recurrent spontaneous abortion is often unclear and may be multifactorial, with much controversy regarding diag-nosis and treatment

TD: The endophenotype concept in psychiatry: etymology and strategic intentions

by Irving I. Gottesman, Ph. D, Todd D. Gould, Endophenotypes Measurable Compo - Am J Psychiatry
"... nents unseen by the unaided eye along the pathway between disease and distal genotype, have emerged as an important concept in the study of complex neuro-psychiatric diseases. An endophenotype may be neurophysiological, biochemical, endocrinological, neuroanatomical, cog-nitive, or neuropsychologica ..."
Abstract - Cited by 288 (3 self) - Add to MetaCart
-nitive, or neuropsychological (including configured self-report data) in nature. En-dophenotypes represent simpler clues to genetic underpinnings than the disease syndrome itself, promoting the view that psychiatric diagnoses can be decomposed or deconstructed, which can result in more straightforward—and successful— genetic

Ohama K. Successful diagnosis of fetal gender using conventional PCR analysis of maternal serum. Clin Chem

by Hiroshi Honda, Norio Miharu, Yoko Ohashi, Koso Ohama
"... plasma and serum. Diagnosis of fetal gender using maternal plasma and serum has been attempted in an effort to develop a new noninvasive method of prenatal diagnosis. Methods: Peripheral blood samples were obtained from 61 pregnant women at 10–17 weeks of gestation before amniocentesis. DNA was extr ..."
Abstract - Cited by 12 (1 self) - Add to MetaCart
plasma and serum. Diagnosis of fetal gender using maternal plasma and serum has been attempted in an effort to develop a new noninvasive method of prenatal diagnosis. Methods: Peripheral blood samples were obtained from 61 pregnant women at 10–17 weeks of gestation before amniocentesis. DNA

Residential and Recreational Acquisition of Possible Estuary-Associated Syndrome: A New Approach to Successful Diagnosis and Treatment

by Ritchie C. Shoemaker
"... one or more toxins that kill fish and adversely affect human health. In the current study we investigated the potential for undiagnosed cases of possible estuary-associated syndrome (PEAS), as termed by the Centers for Disease Control and Prevention (CDC), in a population that had residential and/or ..."
Abstract - Cited by 2 (0 self) - Add to MetaCart
one or more toxins that kill fish and adversely affect human health. In the current study we investigated the potential for undiagnosed cases of possible estuary-associated syndrome (PEAS), as termed by the Centers for Disease Control and Prevention (CDC), in a population that had residential and/or recreational exposure to TPC-affected estuaries, but that did not have direct contact with fish kills or lesioned fish. Age-adjusted visual contrast sensitivity (VCS) was significantly lower and the presence of PEAS-associated symptoms was much higher in the estuary cohort (n = 77) than in combined-control cohorts (n = 87), one without exposure to bodies of water (n = 53) and one with exposure to marine waters (n = 34). In the estuary cohort, 37 individuals met the CDC case definition for PEAS and had significantly lower VCS than non-PEAS cases. The VCS improved and symptoms abated after 2 weeks of treatment with cholestyramine. Cholestyramine, the original drug approved for treatment of hypercholesterolemia, has previously been reported to enhance the elimination rates of a variety of toxins, presumably by interruption of enterohepatic recirculation through toxin entrapment in its polymeric structure and/or anion-exchange process. Control studies showed that repeated VCS testing alone did not improve VCS scores and that cholestyramine treatment did not affect VCS in patients with elevated cholesterol levels. These results suggested that a) susceptible

SUCCESSFUL DIAGNOSIS AND SURGICAL REMOVAL OF FOREIGN BODY (SEWING NEEDLE) IN ONE MONTH OLD KID—A CASE REPORT

by Munish Gupta
"... A non descriptive one month old goat kid was presented to the veterinary Polyclinic Shahpur with a history of anorexia from last two days along with restlessness with the tendency to lie down and stand up frequently along with bleating sounds. On clinical examination, the rectal temperature was norm ..."
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A non descriptive one month old goat kid was presented to the veterinary Polyclinic Shahpur with a history of anorexia from last two days along with restlessness with the tendency to lie down and stand up frequently along with bleating sounds. On clinical examination, the rectal temperature was normal but the animal was dull and depressed. On palpation of abdomen/ pressing at level of lumber vertebra, animal felt intensive pain and tend to lie down with intense bleating sounds. The animal also showed respiratory distress. Further on radiographic examination, a clear radiodense foreign body (sewing needle) about 5 cm. In length was found embedded inside the abdomen with its base embedded inside the abdomen and the tip was found embedded in the lumber muscles at the level of L-5 vertebra.

A Step toward Tuberculosis Elimination in a Low-Incidence Country: Successful Diagnosis and Treatment of Latent Tuberculosis Infection in a Refugee Clinic

by Elissa Rennert-May , Elisabeth Hansen , Toktam Zadeh , Valerie Krinke , Stan Houston , Ryan Cooper
"... Objectives. Approximately 65 percent of tuberculosis (TB) cases in Canada each year occur from reactivation in foreign-born individuals. Refugees are at high risk after immigration. Routine screening of this population for latent TB infection (LTBI) is generally considered infeasible. We evaluated ..."
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the outcome of LTBI screening and treatment amongst refugees. Methods. Government-sponsored refugees in Edmonton are seen at the New Canadians' Clinic and screened for TB and LTBI. We reviewed records of patients between 2009 and 2011. Completeness of initial assessment, diagnosis of latent infection

ELM-ART: An Adaptive Versatile System for Web-Based Instruction

by Gerhard Weber, Peter Brusilovsky - Int’l J. Artificial Intelligence in Education , 2001
"... Abstract: This paper discusses the problems of developing versatile adaptive and intelligent learning systems that can be used in the context of practical Web-based education. We argue that versatility is an important feature of successful Web-based education systems. We introduce ELM-ART, an intell ..."
Abstract - Cited by 197 (13 self) - Add to MetaCart
Abstract: This paper discusses the problems of developing versatile adaptive and intelligent learning systems that can be used in the context of practical Web-based education. We argue that versatility is an important feature of successful Web-based education systems. We introduce ELM

Using Anytime Algorithms in Intelligent Systems

by Shlomo Zilberstein , 1996
"... Anytime algorithms give intelligent systems the capability to trade deliberation time for quality of results. This capability is essential for successful operation in domains such as signal interpretation, real-time diagnosis and repair, and mobile robot control. What characterizes these domains i ..."
Abstract - Cited by 193 (8 self) - Add to MetaCart
Anytime algorithms give intelligent systems the capability to trade deliberation time for quality of results. This capability is essential for successful operation in domains such as signal interpretation, real-time diagnosis and repair, and mobile robot control. What characterizes these domains
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