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Summary Background: Subtle cognitive and neurological

by F. Dick, S. Semple, A. Osborne, A. Soutar, A. Seaton, J. W. Cherrie, L. G. Walker, N. Haites , 2002
"... impairments have been found in some workers exposed to organic solvents. Whether these effects occur at or below current legal limits for occupational exposure is controversial. Aim: To determine whether occupational solvent exposure is associated with neuropsychological impairment and whether such ..."
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impairments have been found in some workers exposed to organic solvents. Whether these effects occur at or below current legal limits for occupational exposure is controversial. Aim: To determine whether occupational solvent exposure is associated with neuropsychological impairment and whether

Another advanced test of theory of mind: Evidence from very high functioning adults with autism or Asperger syndrome

by Simon Baron-cohen, Therese Jolliffe, Catherine Mortimore, Mary Robertson - Journal of Child Psychology and Psychiatry , 1997
"... Previous studies have found a subgroup of people with autism or Asperger Syndrome who pass second-order tests of theory of mind. However, such tests have a ceiling in developmental terms corresponding to a mental age of about 6 years. It is therefore impossible to say if such individuals are intact ..."
Abstract - Cited by 208 (17 self) - Add to MetaCart
or impaired in their theory of mind skills. We report the performance of very high functioning adults with autism or Asperger Syndrome on an adult test of theory of mind ability. The task involved inferring the mental state of a person just from the information in photographs of a person's eyes. Relative

Strategies; Neurological Impairments; *Neurological

by Raymond S. Gray, Jeffrey W
"... Research has suggested that the two hemispheres of the brain serve specialized functions, with the most recent studies portraying the left hemisphere as processing information in a linear, serial, or sequential manner and the right hemisphere as processing information in a holistic, concrete, or vis ..."
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, or visual mode. Although few systematic studies have attempted to integrate cognitive and neurological points of view, Paivio's (1971) portrayal of two distinct, yet interactive memory systems may be consistent with established hemispheric differences in functioning found in the human brain. Research

Methyl mercury in fish: A review of residue levels, fish consumption and regulatory action in the United States. Environ. Health Perspectives 68:203208

by Linda Tollefson, Frank Cordle , 1986
"... The dangers associated with the consumption of large amounts of methylmercury in fish are well recognized, and there is some evidence to suggest that methylmercury may be the cause of subtle neurological impairments when ingested at even low to moderate levels, particularly the prenatal and early ch ..."
Abstract - Cited by 14 (0 self) - Add to MetaCart
The dangers associated with the consumption of large amounts of methylmercury in fish are well recognized, and there is some evidence to suggest that methylmercury may be the cause of subtle neurological impairments when ingested at even low to moderate levels, particularly the prenatal and early

Neurology,

by Fabienne Loup, Heinz-gregor Wieser, Yasuhiro Yonekawa, Adriano Aguzzi, Jean-marc Fritschy, Neurosurgery
"... Temporal lobe epilepsy (TLE) is associated with impaired inhibitory neurotransmission. Studies in animal models suggest that GABA A receptor dysfunction contributes to epileptogenesis. To understand the mechanisms underlying TLE in humans, it is fundamental to determine whether and how GABA A recept ..."
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Temporal lobe epilepsy (TLE) is associated with impaired inhibitory neurotransmission. Studies in animal models suggest that GABA A receptor dysfunction contributes to epileptogenesis. To understand the mechanisms underlying TLE in humans, it is fundamental to determine whether and how GABA A

Cpd-1 Null Mice Display a Subtle Neurological

by Rupinder K. Kular, Rocky G. Gogliotti, Puneet Opal , 2010
"... Background: CPD1 (also known as ANP32-E) belongs to a family of evolutionarily conserved acidic proteins with leucine rich repeats implicated in a variety of cellular processes regulating gene expression, vesicular trafficking, intracellular signaling and apoptosis. Because of its spatiotemporal exp ..."
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expression pattern, CPD1 has been proposed to play an important role in brain morphogenesis and synaptic development. Methodology/Principal Findings: We have generated CPD1 knock-out mice that we have subsequently characterized. These mice are viable and fertile. However, they display a subtle neurological

Subtle Alterations in PCNA-Partner Interactions Severely Impair DNA Replication and Repair

by Yearit Fridman, Niv Palgi, Daniel Dovrat, Shay Ben-aroya, Philip Hieter, Amir Aharoni , 2010
"... The robustness of complex biological processes in the face of environmental and genetic perturbations is a key biological trait. However, while robustness has been extensively studied, little is known regarding the fragility of biological processes. Here, we have examined the susceptibility of DNA r ..."
Abstract - Cited by 1 (0 self) - Add to MetaCart
that increases in PCNA-partner interaction affinities led to severe in vivo phenotypic defects. Surprisingly, such defects are much more severe than those induced by complete abolishment of the respective interactions. Thus, the subtle and tunable nature of these affinity perturbations produced different

Subtle Deficits in Instrumental Activities of Daily Living in Subtypes of Mild Cognitive Impairment

by Dement Geriatr, Cogn Disord, Edmond Teng, Brian W. Becker, Ellen Woo, Jeffrey L. Cummings, Po H. Lu C , 2010
"... Mild cognitive impairment � Functional impairment � Activities of daily living � Memory performance � Executive function domains. These cross-sectional findings support previous longitudinal reports suggesting that cognitive and functional impairments in MCI may be independently associated with deme ..."
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Mild cognitive impairment � Functional impairment � Activities of daily living � Memory performance � Executive function domains. These cross-sectional findings support previous longitudinal reports suggesting that cognitive and functional impairments in MCI may be independently associated

The ears of the hippopotamus: manifestations, determinants, and estimates of the malaria

by Joel G. Breman
"... Abstract. Malarious patients experience asymptomatic parasitemia; acute febrile illness (with cerebral damage, anemia, respiratory distress, hypoglycemia); chronic debilitation (anemia, malnutrition, nervous system–related sequelae); and complications of pregnancy (anemia, low birth weight, increase ..."
Abstract - Cited by 130 (0 self) - Add to MetaCart
to understanding and preventing malaria-induced anemia, hypoglycemia, effects on pregnancy, and neurologic and developmental impairment. To decrease and stop transmission of this intolerable scourge, there is an urgent need for malaria vaccines, newer drugs, and better vector control methods as well as the ability

JG: Gaps in the childhood malaria burden in Africa: cerebral malaria, neurological sequelae, anemia, respiratory distress, hypoglycemia, and complications of pregnancy. Am J Trop Med Hyg 2001

by Sean C. Murphy, Joel, G. Breman
"... Abstract. Evaluations of the African childhood malaria burden do not fully quantify the contributions of cerebral malaria (CM), CM-associated neurological sequelae, malarial anemia, respiratory distress, hypoglycemia, and pregnancy-related complications. We estimated the impact of these malaria mani ..."
Abstract - Cited by 99 (0 self) - Add to MetaCart
and 110,000 (�19 % case fatality rate [CFR]) die. Childhood survivors of CM experience developmental and behavioral impairments: each year, 9,000–19,000 children ( � 2 % of survivors of CM) � 5 years of age in Africa experience neurological complications lasting � 6 months. Severe malarial anemia heavily
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