Substructure similarity search is to retrieve graphs that approximately contain a given query graph. It has many applications, e.g., detecting similar functions among chemical compounds. The problem is challenging as even testing subgraph containment between two graphs is NP-complete. Hence

matching is often too restrictive, similarity search of complex structures becomes a vital operation that must be supported efficiently. In this paper, we investigate the issues of substructure similarity search using indexed features in graph databases. By transforming the edge relaxation ratio of a query

the sequences and e ciently answer similarity queries. We provide experimental results which show that our method is superior to search based on sequential scanning. Our experiments show that a few coefficients (1-3) are adequate to provide good performance. The performance gain of our method increases

We investigate new approaches for frequent graph-based pattern mining in graph datasets and propose a novel algorithm called gSpan (graph-based Substructure pattern mining) , which discovers frequent substructures without candidate generation. gSpan builds a new lexicographic order among graphs

The nearest- or near-neighbor query problems arise in a large variety of database applications, usually in the context of similarity searching. Of late, there has been increasing interest in building search/index structures for performing similarity search over high-dimensional data, e.g., image

A new access meth d, called M-tree, is proposed to organize and search large data sets from a generic "metric space", i.e. whE4 object proximity is only defined by a distance function satisfyingth positivity, symmetry, and triangle inequality postulates. We detail algorith[ for insertion

ABSTRACT The BLAST programs are widely used tools for searching protein and DNA databases for sequence similarities. For protein comparisons, a variety of definitional, algorithmic and statistical refinements described here permits the execution time of the BLAST programs to be decreased

We describe a highly functional prototype system for searching by visual features in an image database. The VisualSEEk system is novel in that the user forms the queries by diagramming spatial arrangements of color regions. The system finds the images that contain the most similar arrangements

A method to correlate the uninterpreted tandem mass spectra of peptides produced under low energy (lo-50 eV) collision conditions with amino acid sequences in the Genpept database has been developed. In this method the protein database is searched to identify linear amino acid sequences within a

We investigate the “generalized second-price” (GSP) auction, a new mechanism used by search engines to sell online advertising. Although GSP looks similar to the Vickrey-Clarke-Groves (VCG) mechanism, its properties are very different. Unlike the VCG mechanism, GSP generally does not have