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2,006
Development and Evaluation of Liquid and Solid Self-Emulsifying Drug Delivery Systems for Atorvastatin
"... Abstract: The objective of this work was to design and characterize liquid and solid self-emulsifying drug delivery systems (SEDDS) for poorly soluble atorvastatin. To optimize the composition of liquid atorvastatin-SEDDS, solubility tests, pseudoternary phase diagrams, emulsification studies and o ..."
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Abstract: The objective of this work was to design and characterize liquid and solid self-emulsifying drug delivery systems (SEDDS) for poorly soluble atorvastatin. To optimize the composition of liquid atorvastatin-SEDDS, solubility tests, pseudoternary phase diagrams, emulsification studies
Design and optimization of chlordiazepoxide solid self-microemulsifying drug delivery system
, 2011
"... ISSN: 0974-6943 Available online through www.jpronline.info *Corresponding author. ..."
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ISSN: 0974-6943 Available online through www.jpronline.info *Corresponding author.
Construction of an equalized cDNA library from human brain by semi-solid self-hybridization system DNA
- Res
, 1994
"... A cDNA library enriched in clones for mRNA species (an equalized cDNA library) was constructed from human brain employing semi-solid self-hybridization system and cDNA amplification by in vitro transcription. Sequence analysis of the clones in the cDNA library indicated that (1) clones representing ..."
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A cDNA library enriched in clones for mRNA species (an equalized cDNA library) was constructed from human brain employing semi-solid self-hybridization system and cDNA amplification by in vitro transcription. Sequence analysis of the clones in the cDNA library indicated that (1) clones representing
DEVELOPMENT OF SOLID SELF EMULSIFYING DRUG DELIVERY SYSTEMS CONTAINING EFAVIRENZ: IN VITRO AND IN VIVO EVALUATION
, 975
"... Vijaya College of Pharmacy, Hayath nagar, Hyderabad-501511 Efavirenz is a drug with an absorption window. Its oral bioavailability is 40-50%. The aim of this work was to formulate solid self-emulsifying drug delivery system to improve the solubility and bioavailability of efavirenz. Solubility of Ef ..."
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Vijaya College of Pharmacy, Hayath nagar, Hyderabad-501511 Efavirenz is a drug with an absorption window. Its oral bioavailability is 40-50%. The aim of this work was to formulate solid self-emulsifying drug delivery system to improve the solubility and bioavailability of efavirenz. Solubility
Preparation and in vivo Evaluation of a Sildenafil Lactate-loaded Solid Self-emulsifying Drug Delivery System
, 2011
"... ABSTRACT − To develop a sildenafil lactate-loaded solid self-emulsifying drug delivery system (SEDDS) with a fast onset of action and immediate action of erection, sildenafil lactate (0.3 g), which was prepared using a spray dryer, was dissolved in 4.7 g of the mixture of glyceryl monooleate/Transcu ..."
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ABSTRACT − To develop a sildenafil lactate-loaded solid self-emulsifying drug delivery system (SEDDS) with a fast onset of action and immediate action of erection, sildenafil lactate (0.3 g), which was prepared using a spray dryer, was dissolved in 4.7 g of the mixture of glyceryl monooleate
Effects of Spray-Drying and Choice of Solid Carriers on Concentrations of Labrasol ® and Transcutol ® in Solid Self-Microemulsifying Drug Delivery Systems (SMEDDS)
, 2013
"... molecules ..."
International Journal of Biopharmaceutics SOLID SELF-EMULSIFYING DRUG DELIVERY SYSTEM: PREPARATION TECHNIQUES AND DOSAGE FORMS
, 2014
"... ABSTRACT Drugs are most often administered by the oral route. However, more than 40% of new chemical entities exhibit poor aqueous solubility, resulting in unsatisfactory oral drug delivery. Recently, much attention has been focused on Selfemulsifying drug delivery systems (SEDDS) are usually used ..."
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to improve the bioavailability of hydrophobic drugs. Conventional SEDDS, however, are mostly prepared in a liquid form, which can produce some disadvantages. Accordingly, solid SEDDS (S-SEDDS), prepared by solidification of liquid/semisolid self-emulsifying (SE) ingredients into powders, have gained
Research Article A Comparison between Use of Spray and Freeze Drying Techniques for Preparation of Solid Self-Microemulsifying Formulation of Valsartan and In Vitro and In Vivo Evaluation
"... Copyright © 2013 Sanjay Kumar Singh et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The objective of the present study was to ..."
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was to develop self micro emulsifying formulation (SMEF) of valsartan to improve its oral bioavailability. The formulations were screened on the basis of solubility, stability, emulsification efficiency, particle size and zeta potential. The optimized liquid SMEF contains valsartan (20%w/w), Capmul MCM C8 (16%w
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"... Enhancement of oral bioavailability of fenofibrate by solid self-microemulsifying drug delivery systems ..."
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Enhancement of oral bioavailability of fenofibrate by solid self-microemulsifying drug delivery systems
American Journal of Advanced Drug Delivery www.ajadd.co.uk American Journal of Advanced Drug Delivery www.ajadd.co.uk Original Article Formulation and In vitro evaluation of Solid- Self- Emulsifying Drug Delivery System
"... Aim of present study was to develop solid self micro emulsifying drug delivery system (S-SEDDS) with Aerosil 200 for enhancement of dissolution rate of model drug Glibenclamide (GBM). SEDDS was prepared using Capmul MCM C8TM, Cremophor RH 40TM, and Transcutol PTM as oil, surfactant and cosurfactant ..."
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Aim of present study was to develop solid self micro emulsifying drug delivery system (S-SEDDS) with Aerosil 200 for enhancement of dissolution rate of model drug Glibenclamide (GBM). SEDDS was prepared using Capmul MCM C8TM, Cremophor RH 40TM, and Transcutol PTM as oil, surfactant and cosurfactant
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