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Sodium Currents during Differentiation
"... ABSTRACT The electrophysiological properties of a human neuroblastoma cell line, LA-N-5, were studied with the whole-cell configuration of the patch clamp technique before and after the induction of differentiation by retinoic acid, a vitamin A metabolite. Action potentials could be elicited from cu ..."
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current clamped cells before the induction of differentiation, suggesting that some neuroblasts of the developing sympathetic nervous system are excitable. The action potential upstroke was carried by a sodium conductance, which was composed of two types of sodium currents, described by their sensitivity
Analysis of Sodium Current Fluctuations in the Cut-Open Squid Giant Axon
"... Analysis of sodium current fluctuations in the ..."
Inactivation of the sodium channel. I. Sodium current experiments
- J. Gen. Physiol
, 1977
"... with voltage clamp techniques and with the enzyme pronase which selectively destroys inactivation. Comparison of the sodium current before and after pronase treatment shows a lag of several hundred microseconds in the onset of inactivation after depolarization. This lag can also be demonstrated with ..."
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Cited by 72 (9 self)
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with voltage clamp techniques and with the enzyme pronase which selectively destroys inactivation. Comparison of the sodium current before and after pronase treatment shows a lag of several hundred microseconds in the onset of inactivation after depolarization. This lag can also be demonstrated
persistent sodium current
, 2005
"... This is an Open Access article distributed under the terms of the Creative Commons Attribution License ..."
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This is an Open Access article distributed under the terms of the Creative Commons Attribution License
A quantitative description of membrane currents and its application to conduction and excitation in nerve
- Journal of Physiology
, 1952
"... This article concludes a series of papers concerned with the flow of electric current through the surface membrane of a giant nerve fibre (Hodgkin, Huxley & Katz, 1952; Hodgkin & Huxley, 1952 a-c). Its general object is to discu the results of the preceding papers (Part I), to put them into ..."
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Cited by 1924 (2 self)
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in Fig. 1. Current can be carried through the membrane either by charging the membrane capacity or by movement of ion-s through the resistances in parallel with the capacity. The ionic current is divided into components carried by sodium and potassium ions (INa and IK), and a small 'leakage current
Sodium currents in neurons from the rostroventrolateral medulla of the rat
- J Neurophysiol
, 2003
"... R. McCrimmon. Sodium currents in neurons from the rostroventro-lateral medulla of the rat. J Neurophysiol 90: 1635–1642, 2003. First published May 21, 2003; 10.1152/jn.00150.2003. Rapidly inactivat-ing and persistent sodium currents have been characterized in acutely dissociated neurons from the are ..."
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Cited by 10 (8 self)
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R. McCrimmon. Sodium currents in neurons from the rostroventro-lateral medulla of the rat. J Neurophysiol 90: 1635–1642, 2003. First published May 21, 2003; 10.1152/jn.00150.2003. Rapidly inactivat-ing and persistent sodium currents have been characterized in acutely dissociated neurons from
Single Channel Sodium Current in Rat Cardiomyocytes: Use-
, 1988
"... ABBREVIATIONS: INa, macroscopic sodium current (cell segment); V, depolarizing voltage change; o,,, standard deviation of base-line noise; a, standard deviation of event noise; Z, standardized random variable for runs analysis; Na microscopic sodium current (single channel). ..."
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ABBREVIATIONS: INa, macroscopic sodium current (cell segment); V, depolarizing voltage change; o,,, standard deviation of base-line noise; a, standard deviation of event noise; Z, standardized random variable for runs analysis; Na microscopic sodium current (single channel).
Rabbit Cardiac Purkinje Fibers An Effect on Steady State Sodium Currents?
"... fibers. An effect on steady state sodium currents? ..."
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