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The MetaCyc database of metabolic pathways and enzymes and the BioCyc collection of pathway/ genome databases

by Ron Caspi, Tomer Altman, Richard Billington, Kate Dreher, Hartmut Foerster, Carol A. Fulcher, Timothy A. Holl, Ingrid M. Keseler, Anamika Kothari, Aya Kubo, Markus Krummenacker, Mario Latendresse, Lukas A. Mueller, Quang Ong, Suzanne Paley, Pallavi Subhraveti, Daniel S. Weaver, Deepika Weerasinghe, Peifen Zhang, Peter D. Karp - Nucleic Acids Res , 2012
"... The MetaCyc database (MetaCyc.org) is a compre-hensive and freely accessible database describing metabolic pathways and enzymes from all domains of life. MetaCyc pathways are experimentally determined, mostly small-molecule metabolic pathways and are curated from the primary scien-tific literature. ..."
Abstract - Cited by 404 (15 self) - Add to MetaCart
The MetaCyc database (MetaCyc.org) is a compre-hensive and freely accessible database describing metabolic pathways and enzymes from all domains of life. MetaCyc pathways are experimentally determined, mostly small-molecule metabolic pathways and are curated from the primary scien-tific literature

Human DNA methylomes at base resolution show widespread epigenomic differences.

by Ryan Lister , Mattia Pelizzola , Robert H Dowen , R David Hawkins , Gary Hon , Julian Tonti-Filippini , Joseph R Nery , Leonard Lee , Zhen Ye , Que-Minh Ngo , Lee Edsall , Jessica Antosiewicz-Bourget , Ron Stewart , Victor Ruotti , A Harvey Millar , James A Thomson , Bing Ren , Joseph R Ecker - Nature, , 2009
"... DNA cytosine methylation is a central epigenetic modification that has essential roles in cellular processes including genome regulation, development and disease. Here we present the first genome-wide, single-base-resolution maps of methylated cytosines in a mammalian genome, from both human embryo ..."
Abstract - Cited by 401 (6 self) - Add to MetaCart
DNA cytosine methylation is a central epigenetic modification that has essential roles in cellular processes including genome regulation, development and disease. Here we present the first genome-wide, single-base-resolution maps of methylated cytosines in a mammalian genome, from both human

Least Squares Conformal Maps for Automatic Texture Atlas Generation

by Bruno Lévy, Sylvain Petitjean, Nicolas Ray, Jérôme Maillot , 2002
"... A Texture Atlas is an efficient color representation for 3D Paint Systems. The model to be textured is decomposed into charts homeomorphic to discs, each chart is parameterized, and the unfolded charts are packed in texture space. Existing texture atlas methods for triangulated surfaces suffer from ..."
Abstract - Cited by 323 (6 self) - Add to MetaCart
several limitations, requiring them to generate a large number of small charts with simple borders. The discontinuities between the charts cause artifacts, and make it difficult to paint large areas with regular patterns.

One-shot learning of object categories

by Li Fei-fei, Rob Fergus, Pietro Perona - IEEE TRANSACTIONS ON PATTERN ANALYSIS AND MACHINE INTELLIGENCE , 2006
"... Learning visual models of object categories notoriously requires hundreds or thousands of training examples. We show that it is possible to learn much information about a category from just one, or a handful, of images. The key insight is that, rather than learning from scratch, one can take advant ..."
Abstract - Cited by 364 (20 self) - Add to MetaCart
Bayesian approach to models learned from by Maximum Likelihood (ML) and Maximum A Posteriori (MAP) methods. We find that on a database of more than 100 categories, the Bayesian approach produces informative models when the number of training examples is too small for other methods to operate successfully.

MAPS: Multiresolution Adaptive Parameterization of Surfaces

by Aaron W. F. Lee, Wim Sweldens, Peter Schröder, Lawrence Cowsar, David Dobkin , 1998
"... We construct smooth parameterizations of irregular connectivity triangulations of arbitrary genus 2-manifolds. Our algorithm uses hierarchical simplification to efficiently induce a parameterization of the original mesh over a base domain consisting of a small number of triangles. This initial param ..."
Abstract - Cited by 265 (12 self) - Add to MetaCart
We construct smooth parameterizations of irregular connectivity triangulations of arbitrary genus 2-manifolds. Our algorithm uses hierarchical simplification to efficiently induce a parameterization of the original mesh over a base domain consisting of a small number of triangles. This initial

Texture mapping progressive meshes

by Pedro V. Sander, John Snyder, Steven J. Gortler , 2001
"... Given an arbitrary mesh, we present a method to construct a progressive mesh (PM) such that all meshes in the PM sequence share a common texture parametrization. Our method considers two important goals simultaneously. It minimizes texture stretch (small texture distances mapped onto large surface d ..."
Abstract - Cited by 251 (7 self) - Add to MetaCart
Given an arbitrary mesh, we present a method to construct a progressive mesh (PM) such that all meshes in the PM sequence share a common texture parametrization. Our method considers two important goals simultaneously. It minimizes texture stretch (small texture distances mapped onto large surface

Growing Cell Structures - A Self-organizing Network for Unsupervised and Supervised Learning

by Bernd Fritzke - Neural Networks , 1993
"... We present a new self-organizing neural network model having two variants. The first variant performs unsupervised learning and can be used for data visualization, clustering, and vector quantization. The main advantage over existing approaches, e.g., the Kohonen feature map, is the ability of the m ..."
Abstract - Cited by 300 (11 self) - Add to MetaCart
We present a new self-organizing neural network model having two variants. The first variant performs unsupervised learning and can be used for data visualization, clustering, and vector quantization. The main advantage over existing approaches, e.g., the Kohonen feature map, is the ability

High sensitivity mapping of methylated cytosines

by Susan J. Clark, Janet Harrison, Cheryl L. Paul, Marianne Frommer - Nucl. Acids Res , 1994
"... An understanding of DNA methylation and its potential role in gene control during development, aging and cancer has been hampered by a lack of sensitive methods which can resolve exact methylation patterns from only small quantities of DNA. We have now developed a genomic sequencing technique which ..."
Abstract - Cited by 222 (4 self) - Add to MetaCart
, to permit methylation mapping of single genes from small amounts of genomic DNA, readily available from germ cells and early developmental stages.

Improved Use of Continuous Attributes in C4.5

by J. R. Quinlan - Journal of Artificial Intelligence Research , 1996
"... A reported weakness of C4.5 in domains with continuous attributes is addressed by modifying the formation and evaluation of tests on continuous attributes. An MDL-inspired penalty is applied to such tests, eliminating some of them from consideration and altering the relative desirability of all test ..."
Abstract - Cited by 281 (1 self) - Add to MetaCart
tests. Empirical trials show that the modifications lead to smaller decision trees with higher predictive accuracies. Results also confirm that a new version of C4.5 incorporating these changes is superior to recent approaches that use global discretization and that construct small trees with multi

Tilting Operations for Small Screen Interfaces

by Jun Rekimoto , 1996
"... This TechNote introduces a novel interaction technique for small screen devices such as palmtop computers or hand-held electric devices, including pagers and cellular phones. Our proposed method uses the tilt of the device itself as input. Using both tilt and buttons, it is possible to build several ..."
Abstract - Cited by 198 (6 self) - Add to MetaCart
This TechNote introduces a novel interaction technique for small screen devices such as palmtop computers or hand-held electric devices, including pagers and cellular phones. Our proposed method uses the tilt of the device itself as input. Using both tilt and buttons, it is possible to build
Results 11 - 20 of 13,433