Multipoint linkage analysis of quantitative-trait loci (QTLs) has previously been restricted to sibships and small pedigrees. In this article, we show how variance-component linkage methods can be used in pedigrees of arbitrary size and complexity, and we develop a general framework for multipoint

utilizing MS and a host of stable isotope-labeling chemistries have emerged (reviewed in Refs. 1 and 2), offering a departure from traditional techniques employing comparative two-dimensional gel electrophoresis. The ICAT quantitative labeling strategy (3, 4) is perhaps the best-characterized method

The self-organizing map (SOM) is an excellent tool in exploratory phase of data mining. It projects input space on prototypes of a low-dimensional regular grid that can be effectively utilized to visualize and explore properties of the data. When the number of SOM units is large, to facilitate

network control policies. Quantitative performance measures that capture the quality of service requirements in these systems depending on the supported applications are discussed, including throughput maximization, energy consumption minimization, rate utility function maximization as well as general

There are many reports in the literature showing that contact inhibition of growth is affected by the culture medium. A quantitative study of amino acid and glucose uptake by the human diploid cell line, WI-38 was carried out to determine more precisely what effect nutritional factors have

rendering. More significantly, it utilizes the scene depth information to determine the minimum sampling curve in the joint image and geometry space. The minimum sampling curve quantitatively describes the relationship among three key elements in IBR systems: scene complexity (geometrical and textural

ABSTRACT. Background: The purpose of this study was to quantify the kinetic aspects of leucine metabolism in the whole body and within the splanchnic region when an amino acid mixture is administered by the enteral route as compared with administration by the parenteral route. Methods: Seven chronically catheterized dogs were studied during an intragastric infusion of L-[1-13C,5N]leucine with 0.24 g of complete amino acid mixture(kg—1 ·hdash 1) for 6 hours. The results are compared with those previously reported for nine dogs studied under essentially identical experimental conditions except that the tracer and amino acid mixtures were given by vein. Results: At the whole body level, the various parameters of leucine metabolism (flux, oxidation, and disappearance into and release from proteins) were not significantly different among animals that were infused enterally and those that were infused parenterally. Leucine metabolism within the splanchnic region and gut was more

the formation of "new " capital and more intensive utilization and accelerated depreciation of "old " capital. Theoretical and quantitative analysis suggests that the shocks and transmission mechanism studied here may be important elements of business cycles. In the real-business cycle

probabilities, utilities and actions, but exploits qualitative information about these elements directly for the derivation of goals. Preferences and judgements of normality are captured in a modal/conditional logic, and a simple model of action is incorporated. Without quantitative information, decision

preset time between 30 and 45min. At the prescribed time, the head is removed and frozen in liquid N,-chilled Freon XII, and the brain sectioned for autoradiography. Local tissue concentrations of ['4C]DG are determined by quantitative autoradiography. Local cerebral glucose consumption