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A comparison of bayesian methods for haplotype reconstruction from population genotype data.

by Matthew Stephens , Peter Donnelly , Dr Matthew Stephens - Am J Hum Genet , 2003
"... In this report, we compare and contrast three previously published Bayesian methods for inferring haplotypes from genotype data in a population sample. We review the methods, emphasizing the differences between them in terms of both the models ("priors") they use and the computational str ..."
Abstract - Cited by 557 (7 self) - Add to MetaCart
In this report, we compare and contrast three previously published Bayesian methods for inferring haplotypes from genotype data in a population sample. We review the methods, emphasizing the differences between them in terms of both the models ("priors") they use and the computational

Multiobjective evolutionary algorithms: a comparative case study and the strength pareto approach

by Eckart Zitzler, Lothar Thiele - IEEE TRANSACTIONS ON EVOLUTIONARY COMPUTATION , 1999
"... Evolutionary algorithms (EA’s) are often well-suited for optimization problems involving several, often conflicting objectives. Since 1985, various evolutionary approaches to multiobjective optimization have been developed that are capable of searching for multiple solutions concurrently in a singl ..."
Abstract - Cited by 813 (22 self) - Add to MetaCart
single run. However, the few comparative studies of different methods presented up to now remain mostly qualitative and are often restricted to a few approaches. In this paper, four multiobjective EA’s are compared quantitatively where an extended 0/1 knapsack problem is taken as a basis. Furthermore, we

A Measurement Study of Peer-to-Peer File Sharing Systems

by Stefan Saroiu , P. Krishna Gummadi, Steven D. Gribble , 2002
"... The popularity of peer-to-peer multimedia file sharing applications such as Gnutella and Napster has created a flurry of recent research activity into peer-to-peer architectures. We believe that the proper evaluation of a peer-to-peer system must take into account the characteristics of the peers th ..."
Abstract - Cited by 1254 (15 self) - Add to MetaCart
Napster and Gnutella. In particular, our measurement study seeks to precisely characterize the population of end-user hosts that participate in these two systems. This characterization includes the bottleneck bandwidths between these hosts and the Internet at large, IP-level latencies to send packets

Genomic control for association studies

by B. Devlin, Kathryn Roeder , 1999
"... A dense set of single nucleotide polymorphisms (SNP) covering the genome and an efficient method to assess SNP genotypes are expected to be available in the near future. An outstanding question is how to use these technologies efficiently to identify genes affecting liability to complex disorders. ..."
Abstract - Cited by 480 (13 self) - Add to MetaCart
. To achieve this goal, we propose a statistical method that has several optimal properties: It can be used with casecontrol data and yet, like family-based designs, controls for population heterogeneity; it is insensitive to the usual violations of model assumptions, such as cases failing to be strictly

Haploview: analysis and visualization of LD and haplotype maps

by J. C. Barrett, B. Fry, J. Maller, M. J. Daly - BIOINFORMATICS , 2005
"... Summary: Research over the last few years has revealed significant haplotype structure in the human genome. The characterization of these patterns, particularly in the con-text of medical genetic association studies, is becoming a routine research activity. Haploview is a software pack-age that prov ..."
Abstract - Cited by 1275 (6 self) - Add to MetaCart
Summary: Research over the last few years has revealed significant haplotype structure in the human genome. The characterization of these patterns, particularly in the con-text of medical genetic association studies, is becoming a routine research activity. Haploview is a software pack

Packet Switching In Radio Channels: Part III -- Polling and . . .

by Fouad A. Tobagi, Leonard Kleinrock - IEEE TRANSACTIONS ON COMMUNICATIONS , 1976
"... Here we continue the analytic study of packet switching in radio channels which we reported upon in our two previous papers [ 11, [2]. Again we consider a population of terminals communicating with a central station over a packet-switched radio channel. The allocation of bandwidth among the contend ..."
Abstract - Cited by 517 (5 self) - Add to MetaCart
Here we continue the analytic study of packet switching in radio channels which we reported upon in our two previous papers [ 11, [2]. Again we consider a population of terminals communicating with a central station over a packet-switched radio channel. The allocation of bandwidth among

Increasing Returns and Economic Geography

by Paul Krugman - Journal of Political Economy , 1991
"... This paper develops a simple model that shows how a country can endogenously become differentiated into an industrialized "core" and an agricultural "periphery. " In order to realize scale economies while minimizing transport costs, manufacturing firms tend to locate in the regio ..."
Abstract - Cited by 1811 (7 self) - Add to MetaCart
in the region with larger demand, but the location of demand itself depends on the distribution of manufacturing. Emergence of a core-periphery pattern depends on transportation costs, economies of scale, and the share of manufacturing in national income. The study of economic geography-of the location

An inventory for measuring clinical anxiety: Psychometric properties

by Aaron T. Beck, Norman Epstein, Gary Brown, Robert A. Steer - JOURNAL OF CONSULTING AND CLINICAL PSYCHOLOGY , 1988
"... The development of a 2 l-item self-report inventory for measuring the severity of anxiety in psychia-ric populations i described. The initial item pool f86 items was drawn from three preexisting scales: the Anxiety Checklist, the Physician's Desk Reference Checklist, and the Situational Anxiety ..."
Abstract - Cited by 778 (1 self) - Add to MetaCart
The development of a 2 l-item self-report inventory for measuring the severity of anxiety in psychia-ric populations i described. The initial item pool f86 items was drawn from three preexisting scales: the Anxiety Checklist, the Physician's Desk Reference Checklist, and the Situational

Calibrating noise to sensitivity in private data analysis

by Cynthia Dwork, Frank Mcsherry, Kobbi Nissim, Adam Smith - In Proceedings of the 3rd Theory of Cryptography Conference , 2006
"... Abstract. We continue a line of research initiated in [10, 11] on privacypreserving statistical databases. Consider a trusted server that holds a database of sensitive information. Given a query function f mapping databases to reals, the so-called true answer is the result of applying f to the datab ..."
Abstract - Cited by 649 (60 self) - Add to MetaCart
the ith row of the database and g maps data-base rows to [0, 1]. We extend the study to general functions f, proving that privacy can be preserved by calibrating the standard deviation of the noise according to the sensitivity of the function f. Roughly speaking, this is the amount that any single

Risk and protective factors for alcohol and other drug problems in adolescence and early adulthood: Implications for substance abuse prevention

by J. David Hawkins, Richard E Catalano, Janet Y Miller - Psychological Bulletin , 1992
"... The authors suggest that the most promising route to effective strategies for the prevention of adolescent alcohol and other drug problems is through a risk-focused approach. This approach requires the identification of risk factors for drug abuse, identification of methods by which risk factors hav ..."
Abstract - Cited by 725 (18 self) - Add to MetaCart
have been effectively addressed, and application of these methods to appropriate high-risk and general population samples in controlled studies. The authors review risk and protective factors for drug abuse, assess a number of approaches for drug abuse prevention potential with high-risk groups
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