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Primer3 on the WWW for general users and for biologist programmers

by Steve Rozen, Helen Skaletsky - Methods Mol. Biol , 2000
"... Designing PCR and sequencing primers are essential activities for molecular biologists around the world. This chapter assumes acquaintance with the principles and practice of PCR, as outlined in, for example, refs. 1–4. Primer3 is a computer program that suggests PCR primers for a variety of ..."
Abstract - Cited by 1933 (2 self) - Add to MetaCart
Designing PCR and sequencing primers are essential activities for molecular biologists around the world. This chapter assumes acquaintance with the principles and practice of PCR, as outlined in, for example, refs. 1–4. Primer3 is a computer program that suggests PCR primers for a variety of

Learning Stochastic Logic Programs

by Stephen Muggleton , 2000
"... Stochastic Logic Programs (SLPs) have been shown to be a generalisation of Hidden Markov Models (HMMs), stochastic context-free grammars, and directed Bayes' nets. A stochastic logic program consists of a set of labelled clauses p:C where p is in the interval [0,1] and C is a first-order r ..."
Abstract - Cited by 1194 (81 self) - Add to MetaCart
Stochastic Logic Programs (SLPs) have been shown to be a generalisation of Hidden Markov Models (HMMs), stochastic context-free grammars, and directed Bayes' nets. A stochastic logic program consists of a set of labelled clauses p:C where p is in the interval [0,1] and C is a first

Direct manipulation: a step beyond programming languages

by Ben Shneiderman - Computer , 1983
"... Direct manipulation systems offer the satisfying experience of operating on visible objects. The computer becomes transparent, and users can concentrate on their tasks. ..."
Abstract - Cited by 651 (11 self) - Add to MetaCart
Direct manipulation systems offer the satisfying experience of operating on visible objects. The computer becomes transparent, and users can concentrate on their tasks.

Multiple sequence alignment with the Clustal series of programs

by Ramu Chenna, Hideaki Sugawara, Tadashi Koike, Rodrigo Lopez, Toby J. Gibson, Desmond G. Higgins, Julie D. Thompson - Nucleic Acids Res , 2003
"... The Clustal series of programs are widely used in molecular biology for the multiple alignment of both nucleic acid and protein sequences and for preparing phylogenetic trees. The popularity of the programs depends on a number of factors, including not only the accuracy of the results, but also the ..."
Abstract - Cited by 747 (5 self) - Add to MetaCart
the robustness, portability and user-friendliness of the programs. New features include NEXUS and FASTA format output, printing range numbers and faster tree calculation. Although, Clustal was originally developed to run on a local computer, numerous Web servers have been set up, notably at the EBI

GOLOG: A Logic Programming Language for Dynamic Domains

by Hector J. Levesque, Raymond Reiter, Yves Lespérance, Fangzhen Lin, Richard B. Scherl , 1994
"... This paper proposes a new logic programming language called GOLOG whose interpreter automatically maintains an explicit representation of the dynamic world being modeled, on the basis of user supplied axioms about the preconditions and effects of actions and the initial state of the world. This allo ..."
Abstract - Cited by 628 (74 self) - Add to MetaCart
This paper proposes a new logic programming language called GOLOG whose interpreter automatically maintains an explicit representation of the dynamic world being modeled, on the basis of user supplied axioms about the preconditions and effects of actions and the initial state of the world

KLEE: Unassisted and Automatic Generation of High-Coverage Tests for Complex Systems Programs

by Cristian Cadar, Daniel Dunbar, Dawson Engler
"... We present a new symbolic execution tool, KLEE, capable of automatically generating tests that achieve high coverage on a diverse set of complex and environmentally-intensive programs. We used KLEE to thoroughly check all 89 stand-alone programs in the GNU COREUTILS utility suite, which form the cor ..."
Abstract - Cited by 557 (15 self) - Add to MetaCart
the core user-level environment installed on millions of Unix systems, and arguably are the single most heavily tested set of open-source programs in existence. KLEE-generated tests achieve high line coverage — on average over 90% per tool (median: over 94%) — and significantly beat the coverage

Distributed Computing in Practice: The Condor Experience

by Douglas Thain, Todd Tannenbaum, Miron Livny , 2005
"... Since 1984, the Condor project has enabled ordinary users to do extraordinary computing. Today, the project continues to explore the social and technical problems of cooperative computing on scales ranging from the desktop to the world-wide computational Grid. In this paper, we provide the history a ..."
Abstract - Cited by 551 (8 self) - Add to MetaCart
Since 1984, the Condor project has enabled ordinary users to do extraordinary computing. Today, the project continues to explore the social and technical problems of cooperative computing on scales ranging from the desktop to the world-wide computational Grid. In this paper, we provide the history

Scheduler Activations: Effective Kernel Support for the User-Level Management of Parallelism

by Thomas E. Anderson, Brian N. Bershad, Edward D. Lazowska, Henry M. Levy - ACM Transactions on Computer Systems , 1992
"... Threads are the vehicle,for concurrency in many approaches to parallel programming. Threads separate the notion of a sequential execution stream from the other aspects of traditional UNIX-like processes, such as address spaces and I/O descriptors. The objective of this separation is to make the expr ..."
Abstract - Cited by 475 (21 self) - Add to MetaCart
Threads are the vehicle,for concurrency in many approaches to parallel programming. Threads separate the notion of a sequential execution stream from the other aspects of traditional UNIX-like processes, such as address spaces and I/O descriptors. The objective of this separation is to make

SELF: The power of simplicity

by David Ungar, Randall B. Smith , 1991
"... SELF is an object-oriented language for exploratory programming based on a small number of simple and concrete ideas: prototypes, slots, and behavior. Prototypes combine inheritance and instantiation to provide a framework that is simpler and more flexible than most object-oriented languages. Slots ..."
Abstract - Cited by 640 (19 self) - Add to MetaCart
SELF is an object-oriented language for exploratory programming based on a small number of simple and concrete ideas: prototypes, slots, and behavior. Prototypes combine inheritance and instantiation to provide a framework that is simpler and more flexible than most object-oriented languages

Agents and the Semantic Web

by James Hendler - IEEE INTELLIGENT SYSTEMS , 2001
"... Many challenges of bringing communicating multiagent systems to the Web require ontologies. The integration of agent technology and ontologies could significantly affect the use of Web services and the ability to extend programs to perform tasks for users more efficiently and with less human interve ..."
Abstract - Cited by 2352 (18 self) - Add to MetaCart
Many challenges of bringing communicating multiagent systems to the Web require ontologies. The integration of agent technology and ontologies could significantly affect the use of Web services and the ability to extend programs to perform tasks for users more efficiently and with less human
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