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Functional discovery via a compendium of expression profiles. Cell 102:109
, 2000
"... have been devised to survey gene functions en masse either computationally (Marcotte et al., 1999) or experimentally; among these, highly parallel assays of ..."
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Cited by 537 (8 self)
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have been devised to survey gene functions en masse either computationally (Marcotte et al., 1999) or experimentally; among these, highly parallel assays of
Sorting networks and their applications
, 1968
"... To achieve high throughput rates today's computers perform several operations simultaneously. Not only are I/O operations performed concurrently with computing, but also, in multiprocessors, several computing ..."
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Cited by 660 (0 self)
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To achieve high throughput rates today's computers perform several operations simultaneously. Not only are I/O operations performed concurrently with computing, but also, in multiprocessors, several computing
Introduction to redundant arrays of inexpensive disks
 Proceedings of the IEEE COMPCON
, 1989
"... Abstract Increasmg performance of CPUs and memorres wrll be squandered lf not matched by a sunrlm peformance ourease m II0 Whde the capactty of Smgle Large Expenstve D&T (SLED) has grown rapuily, the performance rmprovement of SLED has been modest Redundant Arrays of Inexpensive Disks (RAID), ba ..."
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Cited by 846 (55 self)
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, and compares RAID to an IBM 3380 and a Fupisu Super Eagle 1 Background: Rlsrng CPU and Memory Performance The users of computers are currently enJoymg unprecedented growth m the speed of computers Gordon Bell said that between 1974 and 1984. smgle chip computers improved m performance by 40 % per year, about
Primitives for the manipulation of general subdivisions and the computations of Voronoi diagrams
 ACM Tmns. Graph
, 1985
"... The following problem is discussed: Given n points in the plane (the sites) and an arbitrary query point 4, find the site that is closest to q. This problem can be solved by constructing the Voronoi diagram of the given sites and then locating the query point in one of its regions. Two algorithms ar ..."
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Cited by 543 (11 self)
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are given, one that constructs the Voronoi diagram in O(n log n) time, and another that inserts a new site in O(n) time. Both are based on the use of the Voronoi dual, or Delaunay triangulation, and are simple enough to be of practical value. The simplicity of both algorithms can be attributed
Sequence Logos: A New Way to Display Consensus Sequences
 Nucleic Acids Res
, 1990
"... INTRODUCTION A logo is "a single piece of type bearing two or more usually separate elements" [1]. In this paper, we use logos to display aligned sets of sequences. Sequence logos concentrate the following information into a single graphic [2]: 1. The general consensus of the sequences. ..."
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Cited by 638 (27 self)
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. National Cancer Institute, Frederick Cancer Research and Development Center, Laboratory of Mathematical Biology, P. O. Box B, Frederick, MD 21701. Internet addresses: toms@ncifcrf.gov and stephens@ncifcrf.gov. y corresponding author 1 2. The order of predominance of the residues at every position. 3
Graphs over Time: Densification Laws, Shrinking Diameters and Possible Explanations
, 2005
"... How do real graphs evolve over time? What are “normal” growth patterns in social, technological, and information networks? Many studies have discovered patterns in static graphs, identifying properties in a single snapshot of a large network, or in a very small number of snapshots; these include hea ..."
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Cited by 534 (48 self)
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increase slowly as a function of the number of nodes (like O(log n) orO(log(log n)). Existing graph generation models do not exhibit these types of behavior, even at a qualitative level. We provide a new graph generator, based on a “forest fire” spreading process, that has a simple, intuitive justification
A Fast Algorithm for Particle Simulations
, 1987
"... this paper to the case where the potential (or force) at a point is a sum of pairwise An algorithm is presented for the rapid evaluation of the potential and force fields in systems involving large numbers of particles interactions. More specifically, we consider potentials of whose interactions a ..."
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Cited by 1145 (19 self)
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are Coulombic or gravitational in nature. For a the form system of N particles, an amount of work of the order O(N 2 ) has traditionally been required to evaluate all pairwise interactions, un F5F far 1 (F near 1F external ), less some approximation or truncation method is used. The algorithm of the present
Analysis of Recommendation Algorithms for ECommerce
, 2000
"... Recommender systems apply statistical and knowledge discovery techniques to the problem of making product recommendations during a live customer interaction and they are achieving widespread success in ECommerce nowadays. In this paper, we investigate several techniques for analyzing largescale pu ..."
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Cited by 515 (26 self)
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Recommender systems apply statistical and knowledge discovery techniques to the problem of making product recommendations during a live customer interaction and they are achieving widespread success in ECommerce nowadays. In this paper, we investigate several techniques for analyzing largescale purchase and preference data for the purpose of producing useful recommendations to customers. In particular, we apply a collection of algorithms such as traditional data mining, nearestneighbor collaborative ltering, and dimensionality reduction on two dierent data sets. The rst data set was derived from the webpurchasing transaction of a large Ecommerce company whereas the second data set was collected from MovieLens movie recommendation site. For the experimental purpose, we divide the recommendation generation process into three sub processes{ representation of input data, neighborhood formation, and recommendation generation. We devise dierenttechniques for dierent sub processes a...
Numerical integration of the Cartesian equations of motion of a system with constraints: molecular dynamics of nalkanes
 J. Comput. Phys
, 1977
"... A numerical algorithm integrating the 3N Cartesian equations of motion of a system of N points subject to holonomic constraints is formulated. The relations of constraint remain perfectly fulfilled at each step of the trajectory despite the approximate character of numerical integration. The method ..."
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Cited by 682 (6 self)
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(MD), which has been widely used in the past for studying simple liquids and solids, has more recently been applied to molecular systems with internal degrees of freedom such as N, [l], H,O [2] and even C,H,, [3]. In applying the MD method three problems arise: (a) the choice of a suitable mechanical
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