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61
Morton Lecture Morton Lecture Form and flexibility in phosphoinositide 3-kinases
"... Abstract PI3Ks (phosphoinositide 3-kinases) have important roles in a variety of cellular activities, including survival, proliferation, growth, shape, migration and intracellular sorting. Consistent with their function in cell survival and growth, the gene for the class Iα PI3K catalytic subunit i ..."
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Abstract PI3Ks (phosphoinositide 3-kinases) have important roles in a variety of cellular activities, including survival, proliferation, growth, shape, migration and intracellular sorting. Consistent with their function in cell survival and growth, the gene for the class Iα PI3K catalytic subunit
Morton Lecture Morton Lecture Phosphoinositides and the regulation of tubular-based endosomal sorting
"... Abstract From the pioneering work of Mabel and Lowell Hokin in the 1950s, the biology of this specific isomer of hexahydroxycyclohexane and its phosphorylated derivatives, in the form of inositol phosphates and phosphoinositides, has expanded to fill virtually every corner of cell biology, whole-or ..."
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-organism physiology and development. In the present paper, I give a personal view of the role played by phosphoinositides in regulating the function of the endosomal network, and, in so doing, highlight some of the basic properties through which phosphoinositides regulate cell function.
Role of Metastasectomy in MRCC
, 2002
"... In 1999 Morton (ref) proposed that “... a number of series show long-term survival following resection of multiple distant metastases for all histologic types of solid neoplasms. This suggests that it is time to reposition surgery in the treatment paradigm for metastatic cancer. ” The principal foc ..."
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In 1999 Morton (ref) proposed that “... a number of series show long-term survival following resection of multiple distant metastases for all histologic types of solid neoplasms. This suggests that it is time to reposition surgery in the treatment paradigm for metastatic cancer. ” The principal
The role of sulfhydryl groups in the bleaching and synthesis of rhodopsin
- KETINENE ISOMERASE
"... A mixture of the carotenoid retinenel and the protein Qpsin, placed in the dark, reacts spontaneously to form the light-sensitive pigment of rod vision, rhodopsin (Wald and Brown, 1950). The nature of the binding between retinenel and opsin governs the conditions under which this synthesis occurs. C ..."
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Cited by 13 (6 self)
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. Conversely the opening of the linkage between opsin and its chromophore as rhodopsin bleaches may have some fundamental connection with the excitation process in rod vision. The demonstration by Morton and his colleagues that retinenex is vitamin A1 aldehyde aroused interest in the general array of aldehyde
Newborns’ face recognition: Role of inner and outer facial features
- Child Development
, 2006
"... Existing data indicate that newborns are able to recognize individual faces, but little is known about what perceptual cues drive this ability. The current study showed that either the inner or outer features of the face can act as sufficient cues for newborns ’ face recognition (Experiment 1), but ..."
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Cited by 13 (0 self)
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enhance our picture of what information newborns actually process and encode when they discriminate, learn, and recognize faces. The study of newborns ’ face processing has played a prominent role in the developmental field within the last two decades (de Haan, 2001; Johnson & Morton, 1991; Pascalis
1 THE ROLES PORCUPINE (Erethizon dorsatum) POPULATIONS WITHIN A HUMAN DOMINATED LANDSCAPE
, 2005
"... express special thanks to everyone who helped me with project design and data collection at the Morton Centre, especially Cate Trueman and Rebecca McQuaid. I would also like to thank Ron Hrushowy for his dedication to the Morton Centre and students who work there. Thanks to my supervisor, Dr. Soren ..."
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express special thanks to everyone who helped me with project design and data collection at the Morton Centre, especially Cate Trueman and Rebecca McQuaid. I would also like to thank Ron Hrushowy for his dedication to the Morton Centre and students who work there. Thanks to my supervisor, Dr. Soren
The Role of Muscles in Arch Support of the Foot
"... l’hoe bOt(’t’httotiisflo of tooclo support- in I-he foot remains coiotroversial despite yettt’s (of imsvcstigtotiooms. Accouchiitg it) ()b0 theory, the torches tore maintaitoed by the cooottmtoc-‘tit)uu of mouscles; accoi’diitg too to second, by I-he st-reiogt-h of passive tissues; and otcco)rd-ims ..."
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. In 1952, Morton ‘#{176}further show’ecl tiutot sttoti( ’ stmtoious t1t)ti the foot are relatively low ’ iii inteiosit-y, falhiiog well w’itloimu the t’ttptthoihiti(’s of the higoonoemsts. His calcultot-ioits showed that oioly acute, hetovy, but
unknown title
"... The aim of this study was to assess the clinical effec-tiveness of ultrasound guided injection in the man-agement of Morton’s Metatarsalgia. Patients clinically diagnosed with interdigital Morton’s neuroma were treated with ultrasound guided injection of local anaesthetic and steroid. Fifty four pat ..."
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, only three have gone on to require surgery for ongoing symp-toms. Although some studies have suggested that nei-ther injection nor imaging have a role in the treat-ment of Morton’s neuroma, this study, however, demonstrates that ultrasound guided placement of local anaesthetic and steroid in either
Term structure models driven by Wiener process and Poisson measures: Existence and positivity
, 2009
"... Abstract. In the spirit of [4], we investigate term structure models driven by Wiener process and Poisson measures with forward curve dependent volatilities. This includes a full existence and uniqueness proof for the corresponding Heath–Jarrow–Morton type term structure equation. Furthermore, we ch ..."
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Cited by 7 (3 self)
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for applications. A key role in our investigation is played by the method of the moving frame, which allows to transform the Heath–Jarrow–Morton–Musiela equation to a time-dependent SDE. Key Words: term structure models driven by Wiener process and Poisson measures, Heath-Jarrow-Morton-Musiela equation, positivity
The Role of Non-Policy Campaign Cues on Presidential Vote Choice: Are Uninformed Voters More Susceptible to these Messages?
"... Political knowledge is unevenly distributed, and those with the highest amounts are concen-trated amongst the politically and socially advantaged. The socioeconomic heterogeneity within the Latino electorate in the United States exemplifies such a distribution. This paper analyzes how political info ..."
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that much of the U.S. electorate is politically uninformed (Gerber and Greene 1998; Husted, Kenny and Morton 1995; Lupia and
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