for their support.

studies. In contrast, maximum-likelihood analysis using a site-specific rates model did recover a tree that is highly congruent with the trees in the two recent studies. If the IRBP third-position sites are removed from the current data set, then combined likelihood analyses obtain a tree that is highly

In this paper, we propose a new method for index-ing large amounts of point and spatial data in high-dimensional space. An analysis shows that index structures such as the R*-tree are not adequate for indexing high-dimensional data sets. The major problem of R-tree-based index structures

The R-tree, one of the most popular access methods for rectangles, is based on the heuristic optimization of the area of the enclosing rectangle in each inner node. By running numerous experiments in a standardized testbed under highly varying data, queries and operations, we were able to design

and capable of generating high quality results. In this paper, we present an efficient algorithm for realistic texture synthesis. The algorithm is easy to use and requires only a sample texture as input. It generates textures with perceived quality equal to or better than those produced by previous techniques

We describe MUSCLE, a new computer program for creating multiple alignments of protein sequences. Elements of the algorithm include fast distance estimation using kmer counting, progressive alignment using a new profile function we call the logexpectation score, and refinement using tree

In tree-based multicast systems, a relatively small number of interior nodes carry the load of forwarding multicast messages. This works well when the interior nodes are highly available, d d cated infrastructure routers but it poses a problem for application-level multicast in peer-to-peer systems

The nearest- or near-neighbor query problems arise in a large variety of database applications, usually in the context of similarity searching. Of late, there has been increasing interest in building search/index structures for performing similarity search over high-dimensional data, e.g., image

additive components are regression trees, and tools for interpreting such \TreeBoost" models are presented. Gradient boosting of regression trees produces competitive, highly robust, interpretable procedures for both regression and classication, especially appropriate for mining less than clean

. The core of this method is a simple hill-climbing algorithm that adjusts tree topology and branch lengths simultaneously. This algorithm starts from an initial tree built by a fast distance-based method and modifies this tree to improve its likelihood at each iteration. Due to this simultaneous adjustment