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Results 1 - 10
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1,932
Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation
- J. Cell
, 1992
"... Abstract. Programmed cell death (PCD) plays a key role in developmental biology and in maintenance of the steady state in continuously renewing tissues. Currently, its existence is inferred mainly from gel electrophoresis of a pooled DNA extract as PCD was shown to be associated with DNA fragmentati ..."
Abstract
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Cited by 691 (0 self)
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Abstract. Programmed cell death (PCD) plays a key role in developmental biology and in maintenance of the steady state in continuously renewing tissues. Currently, its existence is inferred mainly from gel electrophoresis of a pooled DNA extract as PCD was shown to be associated with DNA
The transcriptional program of sporulation in budding yeast
- SCIENCE
, 1998
"... Diploid cells of budding yeast produce haploid cells through the develop-mental program of sporulation, which consists of meiosis and spore morphogenesis. DNA microarrays containing nearly every yeast gene were used to assay changes in gene expression during sporulation. At least seven distinct temp ..."
Abstract
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Cited by 497 (8 self)
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Diploid cells of budding yeast produce haploid cells through the develop-mental program of sporulation, which consists of meiosis and spore morphogenesis. DNA microarrays containing nearly every yeast gene were used to assay changes in gene expression during sporulation. At least seven distinct
Intrinsic and extrinsic motivations: Classic definitions and new directions.
- Contemporary Educational Psychology,
, 2000
"... Intrinsic and extrinsic types of motivation have been widely studied, and the distinction between them has shed important light on both developmental and educational practices. In this review we revisit the classic definitions of intrinsic and extrinsic motivation in light of contemporary research ..."
Abstract
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Cited by 635 (8 self)
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Intrinsic and extrinsic types of motivation have been widely studied, and the distinction between them has shed important light on both developmental and educational practices. In this review we revisit the classic definitions of intrinsic and extrinsic motivation in light of contemporary research
developmental psychopathology
"... Psychoanalysis ushered in this century. Will its influence on developmental psychopathology end in the next? The paper explores some critical obstacles in the way of psychodynamic research, including the fragmentation of psychoanalytic theory, the relative independence of theory from its clinical an ..."
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Psychoanalysis ushered in this century. Will its influence on developmental psychopathology end in the next? The paper explores some critical obstacles in the way of psychodynamic research, including the fragmentation of psychoanalytic theory, the relative independence of theory from its clinical
On Language and Connectionism: Analysis of a Parallel Distributed Processing Model of Language Acquisition
- COGNITION
, 1988
"... Does knowledge of language consist of mentally-represented rules? Rumelhart and McClelland have described a connectionist (parallel distributed processing) model of the acquisition of the past tense in English which successfully maps many stems onto their past tense forms, both regular (walk/walked) ..."
Abstract
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Cited by 415 (13 self)
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as the transfer of activation levels among units and the modification of the weights of their connections. We analyze both the linguistic and the developmental assumptions of the model in detail and discover that (1) it cannot represent certain words, (2) it cannot learn many rules, (3) it can learn rules found
Risk for psychopathology in the children of depressed mothers: A developmental model for understanding mechanisms of transmission. Psychol Rev
"... A large body of literature documents the adverse effects of maternal depression on the functioning and development of offspring. Although investigators have identified factors associated with risk for abnormal development and psychopathology in the children, little attention has been paid to the mec ..."
Abstract
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Cited by 222 (3 self)
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A large body of literature documents the adverse effects of maternal depression on the functioning and development of offspring. Although investigators have identified factors associated with risk for abnormal development and psychopathology in the children, little attention has been paid
A developmental psychopathology perspective on child abuse and neglect
- Journal of the American Academy of Child and Adolescent Psychiatry
, 1995
"... Developmental psychopathology offers an integrative framework for conceptualizing the course of development during adolescence, with particular relevance for understanding continuity and the emer-gence of psychopathology during this and subsequent developmental periods. In this article, the utility ..."
Abstract
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Cited by 151 (2 self)
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Developmental psychopathology offers an integrative framework for conceptualizing the course of development during adolescence, with particular relevance for understanding continuity and the emer-gence of psychopathology during this and subsequent developmental periods. In this article, the utility
The transcriptome of the intraerythrocytic developmental cycle of Plasmodium falciparum
, 2003
"... Plasmodium falciparum is the causative agent of the most burdensome form of human malaria, affecting 200–300 million individuals per year worldwide. The recently sequenced genome of P. falciparum revealed over 5,400 genes, of which 60 % encode proteins of unknown function. Insights into the biochemi ..."
Abstract
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Cited by 213 (12 self)
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into the biochemical function and regulation of these genes will provide the foundation for future drug and vaccine development efforts toward eradication of this disease. By analyzing the complete asexual intraerythrocytic developmental cycle (IDC) transcriptome of the HB3 strain of P. falciparum, we demonstrate
developmental psychopathology
"... The expression psychopathology in general and child psychopathology in particular, is affected by multiple sources of vari-ance. Some of these sources include gender differences, informant differences, and age-related differences. In this paper, we discuss how these sources of variance complicate bo ..."
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both research and clinical management. We argue that the current diagnostic system would be aided by the inclusion of a quantitative axis that can take these sources of variance into account. We reason that the fi elds of genomics and neuroscience are prepared to move the fi eld of developmental psycho-pathology
Emotion, social function, and psychopathology
- Review of General Psychology
, 1998
"... The studies of emotion function and emotional disorders complement one another. In this article, the authors outline relations between the social functions of emotion and four psychological disorders. The authors first present a social-functional account of emotion and argue that emotions help coord ..."
Abstract
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Cited by 103 (26 self)
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to these disorders disrupt interactions and relationships, thus contributing further to the maintenance of the disorder. They conclude by discussing research strategies relevant to the study of emotion, social interaction, and psychopathology. We can be afraid.., or get angry, or feel pity, in general have pleasure
Results 1 - 10
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