Abstract. The growing scale and importance of technological networks throughout the world has highlighted the devastating consequences

, if ubiquitous, would devastate Internet performance. The most problematic TCPs were all independently written, suggesting that correct TCP implementation is fraught with difficulty. Consequently, it behooves the Internet community to develop testing programs and reference implementations. 1 Introduction

such as electric grid, natural gas, water and wastewater industries. While control systems can be vulnerable to a variety of types of cyber attacks that could have devastating consequences, little research has been done to secure the control systems.

and could prove to be an environmental catastrophe with long-lasting and devastating consequences. World-wide cooperation is being sought through the Montreal Protocol to eliminate those

Mosquitoes transmit numerous human and animal diseases with devastating consequences worldwide. Ma-laria is caused by protozoan Plasmodium parasites and transmitted to humans by infected female Anopheles

Due to the widespread devastating consequences of alcohol abuse, a range of pharmacological and non-pharmaceutical in-terventions has been developed to control alcohol-related prob-

Subarachnoid haemorrhage (SAH) is an acute injury to the brain with devastating consequences. Its occurrence at a comparatively young age (compared with ischaemic stroke), poor outcome and

Abstract. Acute renal failure (ARF) secondary to ischemic injury remains a common and potentially devastating problem. A transcriptome-wide interrogation strategy was used to identify renal genes that are induced very early after renal ischemia, whose protein products might serve as novel

to secondary complications. This proves that appropriate high dose glucocorticoid therapy does not promise success of therapy in GCA. An increased awareness of giant cell arteritis should lead to earlier diagnosis and treatment and avoidance of the devastating consequences.

Though type 1 diabetes (T1D) is described to be a disease of acute onset, there is strong evidence for a period of subclinical hyperglycaemia leading up to diagnosis. We describe two clinical cases with a prolonged and insidious onset of T1D, where neurological complications were present at the time of diagnosis. In both, there was an initial rapid and debilitating progression in neurological as well as other microvascular complications, but with a subsequent stabilization in complications over the next few years. These rare and unusual cases illustrate the variable nature of the natural history of T1D as well as its microvascular complications.