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An Interactive Tool for Visualization of Complex Genetic Interactions
"... • DNA sequencing is faster and easier than ever, and much research involves analysis of relationships between different parts of genetic sequences. ..."
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• DNA sequencing is faster and easier than ever, and much research involves analysis of relationships between different parts of genetic sequences.
Complex Genetic Interactions in a Quantitative Trait Locus
"... Whether in natural populations or between two unrelated members of a species, most phenotypic variation is quantitative. To analyze such quantitative traits, one must first map the underlying quantitative trait loci. Next, and far more difficult, one must identify the quantitative trait genes (QTGs) ..."
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Cited by 16 (2 self)
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), characterize QTG interactions, and identify the phenotypically relevant polymorphisms to determine how QTGs contribute to phenotype. In this work, we analyzed three Saccharomyces cerevisiae hightemperature growth (Htg) QTGs (MKT1, END3, and RHO2). We observed a high level of genetic interactions among QTGs
The knowledge complexity of interactive proof systems

, 1989
"... Usually, a proof of a theorem contains more knowledge than the mere fact that the theorem is true. For instance, to prove that a graph is Hamiltonian it suffices to exhibit a Hamiltonian tour in it; however, this seems to contain more knowledge than the single bit Hamiltonian/nonHamiltonian. In th ..."
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Cited by 1246 (39 self)
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/nonHamiltonian. In this paper a computational complexity theory of the "knowledge " contained in a proof is developed. Zeroknowledge proofs are defined as those proofs that convey no additional knowledge other than the correctness of the proposition in question. Examples of zeroknowledge proof systems are given
The genetical evolution of social behaviour
 I. J. Theor. Biol.
, 1964
"... A genetical mathematical model is described which allows for interactions between relatives on one another's fitness. Making use of Wright's Coefficient of Relationship as the measure of the proportion of replica genes in a relative, a quantity is found which incorporates the maximizing p ..."
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Cited by 932 (2 self)
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A genetical mathematical model is described which allows for interactions between relatives on one another's fitness. Making use of Wright's Coefficient of Relationship as the measure of the proportion of replica genes in a relative, a quantity is found which incorporates the maximizing
Genetic Algorithms for Multiobjective Optimization: Formulation, Discussion and Generalization
, 1993
"... The paper describes a rankbased fitness assignment method for Multiple Objective Genetic Algorithms (MOGAs). Conventional niche formation methods are extended to this class of multimodal problems and theory for setting the niche size is presented. The fitness assignment method is then modified to a ..."
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Cited by 633 (15 self)
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to allow direct intervention of an external decision maker (DM). Finally, the MOGA is generalised further: the genetic algorithm is seen as the optimizing element of a multiobjective optimization loop, which also comprises the DM. It is the interaction between the two that leads to the determination of a
Coupled hidden Markov models for complex action recognition
, 1996
"... We present algorithms for coupling and training hidden Markov models (HMMs) to model interacting processes, and demonstrate their superiority to conventional HMMs in a vision task classifying twohanded actions. HMMs are perhaps the most successful framework in perceptual computing for modeling and ..."
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Cited by 501 (22 self)
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We present algorithms for coupling and training hidden Markov models (HMMs) to model interacting processes, and demonstrate their superiority to conventional HMMs in a vision task classifying twohanded actions. HMMs are perhaps the most successful framework in perceptual computing for modeling
Mega: molecular evolutionary genetic analysis software for microcomputers
 CABIOS
, 1994
"... A computer program package called MEGA has been developed for estimating evolutionary distances, reconstructing phylogenetic trees and computing basic statistical quantities from molecular data. It is written in C+ + and is intended to be used on IBM and IBMcompatible personal computers. In this pr ..."
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Cited by 505 (10 self)
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in nucleotide and amino acid sequences. Advanced onscreen sequence data and phylogenetictree editors facilitate publicationquality outputs with a wide range of printers. Integrated and interactive designs, online contextsensitive helps, and a textfile editor make MEGA easy to use.
The particel swarm: Explosion, stability, and convergence in a multidimensional complex space
 IEEE TRANSACTIONS ON EVOLUTIONARY COMPUTION
"... The particle swarm is an algorithm for finding optimal regions of complex search spaces through interaction of individuals in a population of particles. Though the algorithm, which is based on a metaphor of social interaction, has been shown to perform well, researchers have not adequately explained ..."
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Cited by 852 (10 self)
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The particle swarm is an algorithm for finding optimal regions of complex search spaces through interaction of individuals in a population of particles. Though the algorithm, which is based on a metaphor of social interaction, has been shown to perform well, researchers have not adequately
A comparative analysis of selection schemes used in genetic algorithms
 Foundations of Genetic Algorithms
, 1991
"... This paper considers a number of selection schemes commonly used in modern genetic algorithms. Specifically, proportionate reproduction, ranking selection, tournament selection, and Genitor (or «steady state") selection are compared on the basis of solutions to deterministic difference or d ..."
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Cited by 531 (31 self)
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This paper considers a number of selection schemes commonly used in modern genetic algorithms. Specifically, proportionate reproduction, ranking selection, tournament selection, and Genitor (or «steady state") selection are compared on the basis of solutions to deterministic difference
Modeling and simulation of genetic regulatory systems: A literature review
 JOURNAL OF COMPUTATIONAL BIOLOGY
, 2002
"... In order to understand the functioning of organisms on the molecular level, we need to know which genes are expressed, when and where in the organism, and to which extent. The regulation of gene expression is achieved through genetic regulatory systems structured by networks of interactions between ..."
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Cited by 738 (14 self)
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In order to understand the functioning of organisms on the molecular level, we need to know which genes are expressed, when and where in the organism, and to which extent. The regulation of gene expression is achieved through genetic regulatory systems structured by networks of interactions between
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