At the end of a thoughtful article on the future of nuclear war, Wiesner and York (1) concluded that: “Both sides in the arms race are... confronted by the dilemma of steadily increasing military power and steadily de-creasing national security. It is our considered professional judgment that this dilemma has no technical solution. If the great powers continue to look for solutions in the area of science and technology only, the result will be to worsen the situation.” I would like to focus your attention not on the subject of the article (national secu-rity in a nuclear world) but on the kind of conclusion they reached, namely that there

corresponds to knowledge that is "distributed" among the members of the group, while common knowledge corresponds to a fact being "publicly known". The relationship between common knowledge and a variety of desirable actions in a distributed system is illustrated. Furthermore, it is shown

This study examines the empirical relattonship between the return and the total market value of NYSE common stocks. It is found that smaller firms have had htgher risk adjusted returns, on average, than larger lirms. This ‘size effect ’ has been in existence for at least forty years and is evidence

We present a new and more symmetric version of the circumscription method of nonmonotonic reasoning first described in (McCarthy 1980) and some applications to formalizing common sense knowledge. The applications in this paper are mostly based on minimizing the abnormality of different aspects

The classification rules induced by machine learning systems are judged by two criteria: their classification accuracy on an independent test set (henceforth "accuracy"), and their complexity. The relationship between these two criteria is, of course, of keen interest to the machine learning community. There are in the literature some indications that very simple rules may achieve surprisingly high accuracy on many datasets. For example, Rendell occasionally remarks that many real world datasets have "few peaks (often just one) " and so are "easy to learn" (Rendell & Seshu, 1990, p.256). Similarly, Shavlik et al. (1991) report that, with certain qualifications, "the accuracy of the perceptron is hardly distinguishable from the more complicated learning algorithms " (p.134). Further evidence is provided by studies of pruning methods (e.g. Buntine & Niblett, 1992; Clark & Niblett, 1989; Mingers, 1989), where accuracy is rarely seen to decrease as pruning becomes more severe (for example, see Table 1) 1. This is so even when rules are pruned to the extreme, as happened with the "Err-comp " pruning method in Mingers (1989). This method produced the most accurate decision trees, and in four of the five domains studied these trees had only 2 or 3 leaves

The specificities of 28 commercially available compounds reported to be relatively selective inhibitors of particular serine� threonine-specific protein kinases have been examined against a large panel of protein kinases. The compounds KT 5720, Rottlerin and quercetin were found to inhibit many protein kinases, sometimes much more potently than their presumed targets, and conclusions drawn from their use in cell-based experiments are likely to be erroneous. Ro 318220 and related bisindoylmaleimides, as well as H89, HA1077 and Y 27632, were more selective inhibitors, but still inhibited two or more protein kinases with similar potency. LY 294002 was found to inhibit casein kinase-2 with similar potency to phosphoinositide (phosphatidylinositol) 3-kinase. The compounds with the most

Cointegrated multiple time series share at least one common trend. Two tests are developed for the number of common stochastic trends (i.e., for the order of cointegration) in a multiple time series with and without drift. Both tests involve the roots of the ordinary least squares coefficient

Individual investors who hold common stocks directly pay a tremendous performance penalty for active trading. Of 66,465 households with accounts at a large discount broker during 1991 to 1996, those that trade most earn an annual return of 11.4 percent, while the market returns 17.9 percent

WordNet is an on-line lexical reference system whose design is inspired by current

workload generation tool which mimics a set of real users accessing a server. The tool, called Surge (Scalable URL Reference Generator) generates references matching empirical measurements of 1) server file size distribution; 2) request size distribution; 3) relative file popularity; 4) embedded file