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Results 1 - 10
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35,623
Hierarchical Models of Object Recognition in Cortex
, 1999
"... The classical model of visual processing in cortex is a hierarchy of increasingly sophisticated representations, extending in a natural way the model of simple to complex cells of Hubel and Wiesel. Somewhat surprisingly, little quantitative modeling has been done in the last 15 years to explore th ..."
Abstract
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Cited by 836 (84 self)
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the biological feasibility of this class of models to explain higher level visual processing, such as object recognition. We describe a new hierarchical model that accounts well for this complex visual task, is consistent with several recent physiological experiments in inferotemporal cortex and makes testable
The structure and function of complex networks
- SIAM REVIEW
, 2003
"... Inspired by empirical studies of networked systems such as the Internet, social networks, and biological networks, researchers have in recent years developed a variety of techniques and models to help us understand or predict the behavior of these systems. Here we review developments in this field, ..."
Abstract
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Cited by 2600 (7 self)
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Inspired by empirical studies of networked systems such as the Internet, social networks, and biological networks, researchers have in recent years developed a variety of techniques and models to help us understand or predict the behavior of these systems. Here we review developments in this field
The Protein Data Bank
- Nucleic Acids Res
, 2000
"... The Protein Data Bank (PDB; http://www.rcsb.org/pdb/ ) is the single worldwide archive of structural data of biological macromolecules. This paper describes the goals of the PDB, the systems in place for data deposition and access, how to obtain further information, and near-term plans for the futur ..."
Abstract
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Cited by 1387 (24 self)
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The Protein Data Bank (PDB; http://www.rcsb.org/pdb/ ) is the single worldwide archive of structural data of biological macromolecules. This paper describes the goals of the PDB, the systems in place for data deposition and access, how to obtain further information, and near-term plans
Using Bayesian networks to analyze expression data
- Journal of Computational Biology
, 2000
"... DNA hybridization arrays simultaneously measure the expression level for thousands of genes. These measurements provide a “snapshot ” of transcription levels within the cell. A major challenge in computational biology is to uncover, from such measurements, gene/protein interactions and key biologica ..."
Abstract
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Cited by 1088 (17 self)
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DNA hybridization arrays simultaneously measure the expression level for thousands of genes. These measurements provide a “snapshot ” of transcription levels within the cell. A major challenge in computational biology is to uncover, from such measurements, gene/protein interactions and key
Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation
- J. Cell
, 1992
"... Abstract. Programmed cell death (PCD) plays a key role in developmental biology and in maintenance of the steady state in continuously renewing tissues. Currently, its existence is inferred mainly from gel electrophoresis of a pooled DNA extract as PCD was shown to be associated with DNA fragmentati ..."
Abstract
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Cited by 691 (0 self)
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Abstract. Programmed cell death (PCD) plays a key role in developmental biology and in maintenance of the steady state in continuously renewing tissues. Currently, its existence is inferred mainly from gel electrophoresis of a pooled DNA extract as PCD was shown to be associated with DNA
The Large-Scale Organization of Metabolic Networks
, 2000
"... In a cell or microorganism the processes that generate mass, energy, information transfer, and cell fate specification are seamlessly integrated through a complex network of various cellular constituents and reactions. However, despite the key role these networks play in sustaining various cellular ..."
Abstract
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Cited by 609 (7 self)
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In a cell or microorganism the processes that generate mass, energy, information transfer, and cell fate specification are seamlessly integrated through a complex network of various cellular constituents and reactions. However, despite the key role these networks play in sustaining various cellular
Base-calling of automated sequencer traces using phred. I. Accuracy Assessment
- GENOME RES
, 1998
"... The availability of massive amounts of DNA sequence information has begun to revolutionize the practice of biology. As a result, current large-scale sequencing output, while impressive, is not adequate to keep pace with growing demand and, in particular, is far short of what will be required to obta ..."
Abstract
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Cited by 1653 (4 self)
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The availability of massive amounts of DNA sequence information has begun to revolutionize the practice of biology. As a result, current large-scale sequencing output, while impressive, is not adequate to keep pace with growing demand and, in particular, is far short of what will be required
Large margin methods for structured and interdependent output variables
- JOURNAL OF MACHINE LEARNING RESEARCH
, 2005
"... Learning general functional dependencies between arbitrary input and output spaces is one of the key challenges in computational intelligence. While recent progress in machine learning has mainly focused on designing flexible and powerful input representations, this paper addresses the complementary ..."
Abstract
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Cited by 624 (12 self)
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that solves the optimization problem in polynomial time for a large class of problems. The proposed method has important applications in areas such as computational biology, natural language processing, information retrieval/extraction, and optical character recognition. Experiments from various domains
Aging: a theory based on free radical and radiation chemistry
- J Gerontol
, 1956
"... The phenomenon of growth, decline and death-aging-has been the source of consider-able speculation (1, 8, 10). This cycle seems to be a more or less direct function of the meta-bolic rate and this in turn depends on the species (animal or plant) on which are super-imposed the factors of heredity and ..."
Abstract
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Cited by 637 (2 self)
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and the effects of the stresses and strains of life-which alter the metabolic activity. The universality of this phenomenon sug-gests that the reactions which cause it are basic-ally the same in all living things. Viewing this process in the light of present day free radical and radiation chemistry
biological processes
"... This paper introduces a language that extends the distributed pi-calculus of [7] with time like in [3,4]. This new language, that we call TDpi, is a good tool for describing real-time systems. An example is the interactions in a molecular network, where molecules are separated located processes. Thi ..."
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This paper introduces a language that extends the distributed pi-calculus of [7] with time like in [3,4]. This new language, that we call TDpi, is a good tool for describing real-time systems. An example is the interactions in a molecular network, where molecules are separated located processes
Results 1 - 10
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