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Learning and development in neural networks: The importance of starting small

by Jeffrey L. Elman - Cognition , 1993
"... It is a striking fact that in humans the greatest learnmg occurs precisely at that point in time- childhood- when the most dramatic maturational changes also occur. This report describes possible synergistic interactions between maturational change and the ability to learn a complex domain (language ..."
Abstract - Cited by 531 (17 self) - Add to MetaCart
succeeds only when networks begin with limited working memory and gradually ‘mature ’ to the adult state. This result suggests that rather than being a limitation, developmental restrictions on resources may constitute a necessary prerequisite for mastering certain complex domains. Specifically, successful

Social change and crime rate trends: a routine activity approach

by Lawrence E Cohen, Marcus Felson - American Sociological Review , 1979
"... In this paper we present a "routine activity approach " for analyzing crime rate trends and cycles. Rather than emphasizing the characteristics of offenders, with this approach we concentrate upon the circumstances in which they carry out predatory criminal acts. Most criminal acts require ..."
Abstract - Cited by 680 (5 self) - Add to MetaCart
in the United States 1947-1974 as a byproduct of changes in such variables as labor force participation and single-adult households.

Induction of pluripotent stem cells from adult human fibroblasts by defined factors

by Kazutoshi Takahashi, Koji Tanabe, Mari Ohnuki, Megumi Narita, Tomoko Ichisaka, Kiichiro Tomoda - Cell 2007
"... Successful reprogramming of differentiated human somatic cells into a pluripotent state would allow creation of patient- and disease-specific stem cells. We previously reported generation of induced pluripotent stem (iPS) cells, capable of germline transmission, from mouse somatic cells by transduct ..."
Abstract - Cited by 446 (3 self) - Add to MetaCart
Successful reprogramming of differentiated human somatic cells into a pluripotent state would allow creation of patient- and disease-specific stem cells. We previously reported generation of induced pluripotent stem (iPS) cells, capable of germline transmission, from mouse somatic cells

Theory for the development of neuron selectivity: orientation specificity and binocular interaction in visual cortex

by Elie L. Bienenstock, Leon N Cooper, Paul W. Munro - J. Neurosci , 1982
"... The development of stimulus selectivity in the primary sensory cortex of higher vertebrates is considered in a general mathematical framework. A synaptic evolution scheme of a new kind is proposed in which incoming patterns rather than converging afferents compete. The change in the efficacy of a gi ..."
Abstract - Cited by 432 (20 self) - Add to MetaCart
. The following formal statement then holds: the state of the system converges with probability 1 to points of maximum selectivity in the state space. We next consider the problem of early development of orientation selectivity and binocular interaction in primary visual cortex. Giving the environment

Power laws, Pareto distributions and Zipf’s law

by M. E. J. Newman
"... Many of the things that scientists measure have a typical size or “scale”—a typical value around which individual measurements are centred. A simple example would be the heights of human beings. Most adult human beings are about 180cm tall. There is some variation around this figure, notably dependi ..."
Abstract - Cited by 413 (0 self) - Add to MetaCart
depending on sex, but we never see people who are 10cm tall, or 500cm. To make this observation more quantitative, one can plot a histogram of people’s heights, as I have done in Fig. 1a. The figure shows the heights in centimetres of adult men in the United States measured between 1959 and 1962, and indeed

Development and neurophysiology of mentalizing

by Uta Frith, Christopher D. Frith - Philosophical Transactions of the Royal Society of London. Series B: Biological Sciences , 2003
"... The mentalizing (theory of mind) system of the brain is probably in operation from ca. 18 months of age, allowing implicit attribution of intentions and other mental states. Between the ages of 4 and 6 years explicit mentalizing becomes possible, and from this age children are able to explain the mi ..."
Abstract - Cited by 296 (13 self) - Add to MetaCart
The mentalizing (theory of mind) system of the brain is probably in operation from ca. 18 months of age, allowing implicit attribution of intentions and other mental states. Between the ages of 4 and 6 years explicit mentalizing becomes possible, and from this age children are able to explain

The age distribution of cancer and a multistage theory of carcinogenesis.

by P Armitage , R Doll - Br J Cancer , 1954
"... Attempts to drive theoretical laws from changes in the death rate with age have a long history. They have not, in general, been very fruitful and there has been some hesitation in applying the technique to the study of cancer. Recently, however, two hypotheses about the mechanism of carcinogenesis ..."
Abstract - Cited by 270 (1 self) - Add to MetaCart
in youth might be affected by special factors which were unlikely to operate at later ages and they, therefore, felt justified in basing their hypotheses on the data recorded for adults. Nordling i.e., log rate = 6log t + a constant. In contrast to Fisher and Hollomon's (1951) hypothesis this leads

How does a brain build a cognitive code

by Stephen Grossberg - Psychological Review , 1980
"... This article indicates how competition between afferent data and learned feedback expectancies can stabilize a developing code by buffering committed populations of detectors against continual erosion by new environmental demands. Tille gating phenomena that result lead to dynamically maintained cri ..."
Abstract - Cited by 253 (94 self) - Add to MetaCart
critical peri(Jlds, and to attentional phenomena such as overshadowing in the adult. The fuillctional unit of cognitive coding is suggested to be an adaptive resonance, or amplification and,prolongation of neural activity, that occurs when afferent data and efferent expectancies reach consensus through a

Another advanced test of theory of mind: Evidence from very high functioning adults with autism or Asperger syndrome

by Simon Baron-cohen, Therese Jolliffe, Catherine Mortimore, Mary Robertson - Journal of Child Psychology and Psychiatry , 1997
"... Previous studies have found a subgroup of people with autism or Asperger Syndrome who pass second-order tests of theory of mind. However, such tests have a ceiling in developmental terms corresponding to a mental age of about 6 years. It is therefore impossible to say if such individuals are intact ..."
Abstract - Cited by 208 (17 self) - Add to MetaCart
or impaired in their theory of mind skills. We report the performance of very high functioning adults with autism or Asperger Syndrome on an adult test of theory of mind ability. The task involved inferring the mental state of a person just from the information in photographs of a person's eyes. Relative

Autoimmune disease as a consequence of developmental abnormality of a T cell subpopulation

by Masanao Asano, R Masaaki Toda, Noriko Sakaguchi, Shimon Sakaguchi , 1996
"... Neonatal thymectomy (NTx), especially around day 3 after birth, causes various organ-specific autoimmune diseases in mice. This report shows that: (a) T cells expressing the interleukin 2 receptor cx chains (CD25) ontogenically begin to appear in the normal periphery immediately after day 3, rapidly ..."
Abstract - Cited by 229 (9 self) - Add to MetaCart
, rapidly increasing within 2 wk to nearly adult levels (~10 % of CD3 + cells, especially ofCD4 + cells); (b) NTx on day 3 eliminates CD25 + T cells from the periphery for several days; inoculation immediately after NTx of CD25 + splenic T cells from syngeneic non-Tx adult mice prevents autoimmune
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