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27
Extent of microstructural white matter injury in postconcussive syndrome correlates with impaired cognitive reaction time: a 3T diffusion tensor imaging study of mild traumatic brain injury
- AJNR Am. J. Neuroradiol
, 2008
"... BACKGROUND AND PURPOSE: Diffusion tensor imaging (DTI) may be a useful index of microstructural changes implicated in diffuse axonal injury (DAI) linked to persistent postconcussive symptoms, especially in mild traumatic brain injury (TBI), for which conventional MR imaging techniques may lack sensi ..."
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Cited by 26 (1 self)
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BACKGROUND AND PURPOSE: Diffusion tensor imaging (DTI) may be a useful index of microstructural changes implicated in diffuse axonal injury (DAI) linked to persistent postconcussive symptoms, especially in mild traumatic brain injury (TBI), for which conventional MR imaging techniques may lack
Title of Document: DIFFUSION KURTOSIS MAGNETIC RESONANCE IMAGING AND ITS APPLICATION TO TRAUMATIC BRAIN INJURY
"... Diffusion tensor imaging (DTI) is a popular magnetic resonance imaging technique that provides in vivo information about tissue microstructure, based on the local water diffusion environment. DTI models the diffusion displacement of water molecules in tissue as a Gaussian distribution. In this disse ..."
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. In this dissertation, to mimic the complex nature of water diffusion in brain tissues, a diffusion kurtosis model is used, to incorporate important non-Gaussian diffusion properties. This diffusion kurtosis imaging (DKI) is applied in an experimental traumatic brain injury in a rat model, to study whether it provides
White matter damage and cognitive impairment after traumatic brain injury
"... White matter disruption is an important determinant of cognitive impairment after brain injury, but conventional neuroimaging underestimates its extent. In contrast, diffusion tensor imaging provides a validated and sensitive way of identifying the impact of axonal injury. The relationship between ..."
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cognitive impairment after traumatic brain injury and white matter damage is likely to be complex. We applied a flexible technique-tract-based spatial statistics-to explore whether damage to specific white matter tracts is associated with particular patterns of cognitive impairment. The commonly affected
Transient Global Amnesia Diffusion-Weighted Imaging Lesions and Cerebrovascular Disease
"... Background and Purpose—A hypoxic-ischemic origin of transient global amnesia (TGA) has been suggested on the basis of the observation of infarctlike diffusion-weighted imaging (DWI) abnormalities in some affected individuals. We tested this hypothesis by comparing vascular risk factors, magnetic res ..."
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resonance imaging (MRI) markers of cerebral small-vessel disease, and other evidence of a cerebrovascular disorder between TGA patients with (DWI) and without (DWI) DWI lesions and normal community-based controls. Methods—We retrospectively identified 86 patients hospitalized for TGA (meanSD age, 65
Loss of Microstructural Integrity in the Limbic-Subcortical Networks for Acute Symptomatic Traumatic Brain Injury
"... Previous studies reported discrepant white matter diffusivity in mild traumatic brain injury (mTBI) on the base of Glasgow Coma Scale, which are unreliable for some TBI severity indicators and the frequency of missing documentation in the medical record. In the present study, we adopted the Mayo cl ..."
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Previous studies reported discrepant white matter diffusivity in mild traumatic brain injury (mTBI) on the base of Glasgow Coma Scale, which are unreliable for some TBI severity indicators and the frequency of missing documentation in the medical record. In the present study, we adopted the Mayo
Research Article Loss of Microstructural Integrity in the Limbic-Subcortical Networks for Acute Symptomatic Traumatic Brain Injury
"... Copyright © 2014 Yanan Zhu et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Previous studies reported discrepant white matter d ..."
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diffusivity in mild traumatic brain injury (mTBI) on the base of Glasgow Coma Scale, which are unreliable for some TBI severity indicators and the frequency of missing documentation in the medical record. In the present study, we adopted theMayo classification system for TBI severity. In this system, them
Visualization of Brain Microstructure through Spherical Harmonics Illumination of
"... Fig. 1. Using spherical harmonics lighting functions described in this paper, we visualize spatio-angular fields. In this figure, we use the dataset of a patient suffering from traumatic brain injury. In traditional diffusion tensor imaging, the region around the injury does not exhibit a high contr ..."
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Cited by 1 (0 self)
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Fig. 1. Using spherical harmonics lighting functions described in this paper, we visualize spatio-angular fields. In this figure, we use the dataset of a patient suffering from traumatic brain injury. In traditional diffusion tensor imaging, the region around the injury does not exhibit a high
Bihan. Assessment of the early organization and maturation of infants’ cerebral white matter fiber bundles: a feasibility study using quantitative diffusion tensor imaging and tractography
- tel-00457463, version 1 - 17 Feb 2010
"... The human infant is particularly immature at birth and brain maturation, with the myelination of white matter fibers, is protracted until adulthood. Diffusion tensor imaging offers the possibility to describe non invasively the fascicles spatial organization at an early stage and to follow the cere ..."
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Cited by 20 (1 self)
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of quantification based on reconstructed tracts, split between specific regions, which should be more sensitive to specific changes in a bundle than the conventional approach, based on regionsof-interest. We observed variations in fractional anisotropy and mean diffusivity over the considered developmental period
Early Experience Alters Brain Function and Structure
"... ABSTRACT. Objective. To investigate the effects of early experience on brain function and structure. Methods. A randomized clinical trial tested the neurodevelopmental effectiveness of the Newborn Individualized Developmental Care and Assessment Program (NIDCAP). Thirty preterm infants, 28 to 33 we ..."
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of prenatal care, known prenatal brain lesions (eg, cysts or infarctions), and neonatal seizures. The study-recruitment period extended over 28 months, from May 1, 2000 through August 30, 2002. Ninety infants met study criteria. Of these, 12 families were not approached because of staff unavailability, and 45
RESEARCH ARTICLE A Standardized Method for the Construction of Tracer Specific PET and SPECT Rat Brain Templates: Validation and Implementation
"... High-resolution anatomical image data in preclinical brain PET and SPECT studies is often not available, and inter-modality spatial normalization to an MRI brain template is frequently performed. However, this procedure can be challenging for tracers where sub-stantial anatomical structures present ..."
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of the data set. Additionally, the impact of strain differences, disease uptake patterns (focal and diffuse lesion), and the effect of image and template size on the registration errors were explored. Mean registration errors were 0.70±0.32mm for [18F]FDG (n = 25), 0.23±0.10mm for [11C]flumazenil (n =
Results 1 - 10
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27
