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16
HYPERPHOSPHORYLATED TAU PROTEIN IN THE CEREBROSPINAL FLUID OF PATIENTS WITH ALZHEIMER´S DISEASE AND OTHER DEMENTIAS Preliminary findings
, 2004
"... ABSTRACT- Alzheimer’s disease (AD) is pathologically characterized by the accumulation of amyloid plaques and tau-associated neurofibrillary tangles in the cerebral tissue. The search for antemortem bio-markers is intense including analysis of cerebrospinal fluid (CSF) β-amyloid and tau proteins con ..."
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ABSTRACT- Alzheimer’s disease (AD) is pathologically characterized by the accumulation of amyloid plaques and tau-associated neurofibrillary tangles in the cerebral tissue. The search for antemortem bio-markers is intense including analysis of cerebrospinal fluid (CSF) β-amyloid and tau proteins
Longitudinal Assessment of Amyloid Pathology in Transgenic ArcAb Mice Using Multi-Parametric Magnetic Resonance Imaging
"... Magnetic resonance imaging (MRI) can be used to monitor pathological changes in Alzheimer’s disease (AD). The objective of this longitudinal study was to assess the effects of progressive amyloid-related pathology on multiple MRI parameters in transgenic arcAb mice, a mouse model of cerebral amyloid ..."
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Magnetic resonance imaging (MRI) can be used to monitor pathological changes in Alzheimer’s disease (AD). The objective of this longitudinal study was to assess the effects of progressive amyloid-related pathology on multiple MRI parameters in transgenic arcAb mice, a mouse model of cerebral
Neurobiology of Disease Pathogenic Forms of Tau Inhibit Kinesin-Dependent Axonal Transport through a Mechanism Involving Activation of
"... Aggregated filamentous forms of hyperphosphorylated tau (a microtubule-associated protein) represent pathological hallmarks of Alzheimer’s disease (AD) and other tauopathies.While axonal transport dysfunction is thought to represent a primary pathogenic factor in AD and other neurodegenerative disea ..."
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Aggregated filamentous forms of hyperphosphorylated tau (a microtubule-associated protein) represent pathological hallmarks of Alzheimer’s disease (AD) and other tauopathies.While axonal transport dysfunction is thought to represent a primary pathogenic factor in AD and other neurodegenerative
DOI 10.1007/s00401-008-0373-3 ORIGINAL PAPER Peroxiredoxin 6 in human brain: molecular forms, cellular distribution and association with Alzheimer’s disease pathology
"... Abstract Peroxiredoxin 6 is an antioxidant enzyme and is the 1-cys member of the peroxiredoxin family. Using twodimensional electrophoresis and Western blotting, we have shown for the Wrst time that, in human control and brain tissue of patient’s with Alzheimer’s disease (AD), this enzyme exists as ..."
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Abstract Peroxiredoxin 6 is an antioxidant enzyme and is the 1-cys member of the peroxiredoxin family. Using twodimensional electrophoresis and Western blotting, we have shown for the Wrst time that, in human control and brain tissue of patient’s with Alzheimer’s disease (AD), this enzyme exists
Study Patterns of Brain Magnetic
"... from mild cognitive impairment to AD (10 % to 15% per year)5,6 are providing critical information on functional changes at stages preceding the diagno-sis of AD. The use of markers obtained with structural imaging, in particular magnetic resonance imaging (MRI), are playing a significant role in stu ..."
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fields associated with brain electrical currents originating from activated sets of neurons.8 The MSI, which is generated by superimposing MEG data on an MRI, is a functional imaging technique that combines high temporal and high spatial resolution to detect focal neural activity.9 Alzheimer’s disease
Active Mask Framework for Segmentation of Fluorescence Microscope Images
"... m]]l]]s¶D]]¿÷mB]iv]b]oD]m¶¨]iv]§]iv]r]j]t¿rv]]irj]]t]]m] / | ap]]r¿]ÎNy]s¶D]]mb¶r]ix} Û]Ix]]rd]mb]} p—N]t]o%ism] in]ty]m] / || Û]Is]¡uÎc]rN]]riv]nd]p]*N]m]st¶ I always bow to Śri ̄ Śāradāmbā, the limitless ocean of the nectar of compassion, who bears a rosary, a vessel of nectar, the symbol of ..."
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m]]l]]s¶D]]¿÷mB]iv]b]oD]m¶¨]iv]§]iv]r]j]t¿rv]]irj]]t]]m] / | ap]]r¿]ÎNy]s¶D]]mb¶r]ix} Û]Ix]]rd]mb]} p—N]t]o%ism] in]ty]m] / || Û]Is]¡uÎc]rN]]riv]nd]p]*N]m]st¶ I always bow to Śri ̄ Śāradāmbā, the limitless ocean of the nectar of compassion, who bears a rosary, a vessel of nectar, the symbol
Insufficient Resolution Response in the Hippocampus of a Senescence-Accelerated Mouse Model — SAMP8
, 2014
"... Abstract Aging is the primary risk factor for Alzheimer’s disease (AD), and it is known that inflammation is associated with both aging and AD. To resolve inflammation, biosynthe-sis of the specialized pro-resolving mediators (SPMs) is en-hanced in a programmed and active manner. We investigated the ..."
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Abstract Aging is the primary risk factor for Alzheimer’s disease (AD), and it is known that inflammation is associated with both aging and AD. To resolve inflammation, biosynthe-sis of the specialized pro-resolving mediators (SPMs) is en-hanced in a programmed and active manner. We investigated
unknown title
"... MaGNetIc MINerals are everywhere! Look closely enough at any geological sample and you will find traces of magnetic minerals. From rocks, sediments, and soils, to meteorites, polar ice, and speleothems, detectable quantities of magnetic mineral grains are found virtually everywhere in the natural e ..."
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of neurodegenerative diseases such as Huntington's, Alzheimer's, and Parkinson's. Magnetic minerals are also increasingly being used in medical applications such as targeted gene therapy, whereby therapeutic genes are attached to magnetic nanoparticles and then focused on the target cells via high
Results 1 - 10
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16
