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Results 1 - 10
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42
Artic le Life & Medical Sciences A Connectome Computation System for discovery science of brain
"... Abstract Much like genomics, brain connectomics has rapidly become a core component of most national brain projects around the world. Beyond the ambitious aims of these projects, a fundamental challenge is the need for an efficient, robust, reliable and easy-to-use pipeline to mine such large neuros ..."
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Abstract Much like genomics, brain connectomics has rapidly become a core component of most national brain projects around the world. Beyond the ambitious aims of these projects, a fundamental challenge is the need for an efficient, robust, reliable and easy-to-use pipeline to mine such large
Whole exome sequencing analysis pipeline for the discovery of mutations causative of human rare diseases
"... Abstract Recent advances in high-throughput sequencing technologies have made exome sequencing to be an outstanding tool for finding disease associated mutations at a relatively low cost. However, it is a non-trivial task to transform the vast amount of sequence data into meaningful variants to imp ..."
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to improve disease understanding. Several challenges arise when dealing with this approach, being critical checkpoints the raw read preprocessing, mapping procedure, variant calling and posterior variant selection. A number of computational algorithms and pipelines have been reported for variant analysis
Expeditor: a pipeline for designing primers using human gene structure and livestock animal EST information
- J. Hered
, 2005
"... We have developed software, called Expeditor, that can be used to combine known gene structure information from human and coding sequence information from farm animal species for a streamlined primer design in target farm animal species. This software has many utilities, which include PCR-based SNP ..."
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Cited by 1 (1 self)
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completion of the human genome sequencing project has provided a useful resource for animal genome research due to considerable conservation of genomic organization, including the intron/exon structures, in vertebrates (O’Brien et al. 1997; Zhu et al. 2003). The recent generation of large numbers
Decoding seen and attended motion directions from activity in the human visual cortex.
- Curr. Biol.,
, 2006
"... Summary Functional neuroimaging has successfully identified brain areas that show greater responses to visual motion Results In this study, we investigated whether ensemble activity patterns in the human visual cortex contain sufficiently reliable direction-selective information to decode seen and ..."
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Cited by 50 (0 self)
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Summary Functional neuroimaging has successfully identified brain areas that show greater responses to visual motion Results In this study, we investigated whether ensemble activity patterns in the human visual cortex contain sufficiently reliable direction-selective information to decode seen
ExpressionPlot: A web-based framework for analysis of RNA-Seq and microarray gene expression data Counting Reads for Genes and RNA Processing Events Pre-processing Tasks (Microarrays) Background subtraction and probe normalization
"... Abstract RNA-Seq and microarray platforms have emerged as important tools for detecting changes in gene expression and RNA processing in biological samples. We present ExpressionPlot, a software package consisting of a default back end, which prepares raw sequencing or Affymetrix microarray data, a ..."
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Cited by 1 (0 self)
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(BAM files), or tables of gene expression values and changes generated by other back ends. Once data is pre-processed, the web-based front end allows users to easily browse measures of quality control, plot changes in gene expression and RNA processing, browse hyperlinked tables of changed genes
Reviewed by:
, 2011
"... The Human Connectome Project (HCP) is a major endeavor that will acquire and analyze connectivity data plus other neuroimaging, behavioral, and genetic data from 1,200 healthy adults. It will serve as a key resource for the neuroscience research community, enabling discoveries of how the brain is wi ..."
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Cited by 1 (0 self)
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The Human Connectome Project (HCP) is a major endeavor that will acquire and analyze connectivity data plus other neuroimaging, behavioral, and genetic data from 1,200 healthy adults. It will serve as a key resource for the neuroscience research community, enabling discoveries of how the brain
Automated detection of fMRI artefacts from Shannon entropy distributions
"... As the number of subjects in modern fMRI experiments increases, the use of automated analysis pipelines is becoming more popular, leading to less manual inspection of the data. Here we promote the use of Shannon entropy distributions to discover those datasets in large studies suffering from various ..."
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various artefacts. Entropy distributions of 1444 resting state fMRI datasets from the 1000 Functional Connectomes Project are examined and mean distributions found after each of several different preprocessing steps. Empirically derived envelopes are generated so that significantly outlying datasets may
I Want My Virtual Friends to be Life Size! Adapting Second Life to Multi-Screen Projected Environments
"... Second Life (SL) is a popular 3D online virtual world designed for human interaction (also known as a MUVE, or multi-user virtual environment). It typically supports 60-70 thousand concurrent users. The assets and physical environments within SL are easy to create and use, and the environments thems ..."
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immersive displays such as a CAVETM or other multi projector systems. We wanted to provide a solution that would utilize direct communi-cation between SL viewers and have minimal dependence on 3rd party libraries or interfere with the OpenGL rendering pipeline While there are several ongoing efforts
gaps in the human SNP map Circe Tsui 1,2
, 2003
"... An international effort is underway to generate a comprehensive haplotype map (HapMap) of the human genome represented by an estimated 300 000 to 1 million `tag ' single nucleotide polymorphisms (SNPs). Our analysis indicates that the current human SNP map is not suf®ciently dense to support th ..."
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the HapMap project. For example, 24.6 % of the genome currently lacks SNPs at the minimal density and spacing that would be required to construct even a conservative tag SNP map containing 300 000 SNPs. In an effort to improve the human SNP map, we identi®ed 140 696 additional SNP candidates using a new
Using Skin Segmentation to Improve Similar Product Recommendations in Online Clothing Stores
"... Abstract: Image matching and retrieval in the domain of clothing, as used in online shopping for recommending similar products, is often distracted by the existence of a mannequin/model wearing the product. The existence of a model adds clutter to both the shape and color features of the product. I ..."
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. In this paper, we propose a novel image pre-processing pipeline that minimizes skin and background segments generated from generic GraphCut segmentation. Experiments judged by human subjects show very promising gains of around 23% in retrieval precision of the top 25 similar products compared to the baseline
Results 1 - 10
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