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Results 1 - 10
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118
Predictability modulates human brain response to reward
- Journal of Neuroscience
, 2001
"... Certain classes of stimuli, such as food and drugs, are highly effective in activating reward regions. We show in humans that activity in these regions can be modulated by the predictability of the sequenced delivery of two mildly pleasurable stimuli, orally delivered fruit juice and water. Using fu ..."
Abstract
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Cited by 93 (5 self)
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functional magnetic resonance imaging, the activity for rewarding stimuli in both the nucleus accumbens and medial orbitofrontal cortex was greatest when the stimuli were unpredictable. Moreover, the sub-The pursuit of natural rewards such as food, drink, and sex is a major external influence on human
Myelin water imaging in multiple sclerosis: quantitative correlations with histopathology. Multiple Sclerosis 12
, 2006
"... Various magnetic resonance (MR) techniques are used to study the pathological evolution of demyelinating diseases, such as multiple sclerosis (MS). However, few studies have validated MR derived measurements with histopathology. Here, we determine the correlation of myelin water imaging, an MR measu ..."
Abstract
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Cited by 23 (0 self)
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Various magnetic resonance (MR) techniques are used to study the pathological evolution of demyelinating diseases, such as multiple sclerosis (MS). However, few studies have validated MR derived measurements with histopathology. Here, we determine the correlation of myelin water imaging, an MR
Estimating the Age of Healthy Infants From Quantitative Myelin Water Fraction Maps
"... r r Abstract: The trajectory of the developing brain is characterized by a sequence of complex, nonlinear patterns that occur at systematic stages of maturation. Although significant prior neuroimaging research has shed light on these patterns, the challenge of accurately characterizing brain matura ..."
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-wise estimates of brain age based on magnetic resonance imaging measures sensitive to myelin content. 198 myelin water fraction (VFM) maps were acquired from healthy male and female infants and toddlers, 3 to 48 months of age, and used to train a sigmoidal-based maturational model. The validity of the approach
AJNR Am J Neuroradiol 21:1099–1109, June/July 2000 Review Article Concepts of Myelin and Myelination in Neuroradiology
, 1999
"... Until the advent of MR imaging, knowledge of the structure of myelin and the process of myelination were of little importance to the neuroradiologist. Other than some mild changes in the attenuation of white matter, myelination resulted in no significant alterations of CT (1) or sonographic studies. ..."
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. MR studies, on the other hand, have been increasingly used for pediatric brain imaging. MR imaging’s greater sensitivity to small changes in the water content of brain tissue, to changes in the binding of free water (revealed by magnetization transfer), and to the extent and anisotropy of water
Myelination in Children with Partial Deletions of Chromosome 18q
"... typically developing children with those of children with partial deletions of chromosome 18q (18q). METHODS: Conventional spin-echo MR imaging at 1.9T was used to acquire T1-, T2-, and proton density–weighted images of the brain. From these images, a three-pool model was used to estimate the fracti ..."
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Cited by 1 (1 self)
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typically developing children with those of children with partial deletions of chromosome 18q (18q). METHODS: Conventional spin-echo MR imaging at 1.9T was used to acquire T1-, T2-, and proton density–weighted images of the brain. From these images, a three-pool model was used to estimate
Diffusion-tensor MR imaging of gray and white matter development during normal human brain maturation
- Am. J. Neuroradiol
, 2002
"... BACKGROUND AND PURPOSE: Conventional MR imaging findings of human brain devel-opment are thought to result from decreasing water content, increasing macromolecular concentration, and myelination. We use diffusion-tensor MR imaging to test theoretical models that incorporate hypotheses regarding how ..."
Abstract
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Cited by 15 (0 self)
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BACKGROUND AND PURPOSE: Conventional MR imaging findings of human brain devel-opment are thought to result from decreasing water content, increasing macromolecular concentration, and myelination. We use diffusion-tensor MR imaging to test theoretical models that incorporate hypotheses regarding how
Mapping brain maturation
- Trends Neurosci. 2006
"... Human brain maturation is a complex, lifelong process that can now be examined in detail using neuroimaging techniques. Ongoing projects scan subjects longitudinally with structural magnetic resonance imaging (MRI), enabling the time-course and anatomical sequence of development to be reconstructed ..."
Abstract
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Cited by 33 (1 self)
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Human brain maturation is a complex, lifelong process that can now be examined in detail using neuroimaging techniques. Ongoing projects scan subjects longitudinally with structural magnetic resonance imaging (MRI), enabling the time-course and anatomical sequence of development
© American Society of Neuroradiology MR Assessment of Myelination in Infants and Children: Usefulness of
, 1988
"... A retrospective study was made of 60 patients, 1 month to 3 years old, to determine the normal progression of white matter myelination on MR imaging. All examinations were performed with a 1.5-T unit, and axial T1- and T2-weighted images were evaluated in each patient. Multiple sites in the cerebral ..."
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decrease in the water content of white matter as myelination progresses. Knowledge of these normal myelination patterns is essential in evaluating MR imaging studies in infants and children and in diagnosing delayed myelination. Myelination is a dynamic process in the developing infant brain and for this
doi:10.1155/2011/953806 Research Article Feasibility of Imaging Myelin Lesions in Multiple Sclerosis
"... Copyright © 2011 Maria I. Zavodszky et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The goal of this study was to provide a fe ..."
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feasibility assessment for PET imaging of multiple sclerosis (MS) lesions based on their decreased myelin content relative to the surrounding normal-appearing brain tissue. The imaging agent evaluated for this purpose is a molecule that binds strongly and specifically to myelin basic protein. Physiology
Results 1 - 10
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118
