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conserved microRNA targets in plants

by Uciel Chorostecki, Javier F. Palatnik, Ivo Hofacker , 2014
"... comTAR: a web tool for the prediction and characterization of ..."
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comTAR: a web tool for the prediction and characterization of

comTAR: a web tool for the prediction and characterization of conserved microRNA targets in plants

by Chorostecki U, Palatnik Jf
"... Motivation: MicroRNAs (miRNAs) are major regulators of gene expression in plants and animals. They recognize their target mRNAs by sequence complementarity and guide them to cleavage or translational arrest. So far, the prediction of plant miRNA-target pairs generally relies on the use of empirical ..."
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parameters deduced from known miRNA-target interactions. Results: We developed comTAR, a web tool for the prediction of miRNA targets that is mainly based on the conservation of the potential regulation in different species. We used data generated from a pipeline applied to transcript datasets of 33

mirWIP: microRNA target prediction based on microRNA-containing ribonucleoprotein-enriched transcripts.

by Molly Hammell , Dang Long , Liang Zhang , Andrew Lee , Steven Carmack , Min Han , Ye Ding , Victor Ambros - Nat. Methods. , 2008
"... Target prediction for animal microRNAs (miRNAs) has been hindered by the small number of verified targets available to evaluate the accuracy of predicted miRNA-target interactions. Recently, a dataset of 3,404 miRNA-associated mRNA transcripts was identified by immunoprecipitation of the RNA-induce ..."
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Target prediction for animal microRNAs (miRNAs) has been hindered by the small number of verified targets available to evaluate the accuracy of predicted miRNA-target interactions. Recently, a dataset of 3,404 miRNA-associated mRNA transcripts was identified by immunoprecipitation of the RNA

open access www.bioinformation.net Web Server Volume 6(6) miRTour: Plant miRNA and target prediction tool

by Ivan Milev, Galina Yahubyan, Ivan Minkov, Vesselin Baev , 2011
"... MicroRNAs (miRNAs) are important negative regulators of gene expression in plant and animals, which are endogenously produced from their own genes. Computational comparative approach based on evolutionary conservation of mature miRNAs has revealed a number of orthologs of known miRNAs in different p ..."
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MicroRNAs (miRNAs) are important negative regulators of gene expression in plant and animals, which are endogenously produced from their own genes. Computational comparative approach based on evolutionary conservation of mature miRNAs has revealed a number of orthologs of known miRNAs in different

RESEARCH ARTICLE Open Access Identification of novel microRNAs in Hevea brasiliensis and computational prediction of their targets

by Virginie Gébelin, Xavier Argout, Worrawat Engchuan, Cuifang Duan, Pascal Montoro, Julie Leclercq
"... Background: Plants respond to external stimuli through fine regulation of gene expression partially ensured by small RNAs. Of these, microRNAs (miRNAs) play a crucial role. They negatively regulate gene expression by targeting the cleavage or translational inhibition of target messenger RNAs (mRNAs) ..."
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Background: Plants respond to external stimuli through fine regulation of gene expression partially ensured by small RNAs. Of these, microRNAs (miRNAs) play a crucial role. They negatively regulate gene expression by targeting the cleavage or translational inhibition of target messenger RNAs (m

PsRobot: a web-based plant small RNA meta-analysis toolbox

by Hua-jun Wu, Ying-ke Ma, Tong Chen, Meng Wang, Xiu-jie Wang - Nucleic Acids Res , 2012
"... Small RNAs (smRNAs) in plants, mainly microRNAs and small interfering RNAs, play important roles in both transcriptional and post-transcriptional gene regulation. The broad application of high-throughput sequencing technology has made rou-tinely generation of bulk smRNA sequences in laboratories pos ..."
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possible, thus has significantly increased the need for batch analysis tools. PsRobot is a web-based easy-to-use tool dedicated to the identification of smRNAs with stem-loop shaped precursors (such as microRNAs and short hairpin RNAs) and their target genes/transcripts. It performs fast analysis

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by Universität Zürich, Daniel Hegglin, Prof Dr, Paul I. Ward , 2003
"... zur ..."
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Abstract not found

Evolutionary meandering of intermolecular interactions along the drift barrier

by Michael Lynch , Kyle Hagner - Proceedings of the National Academy of Sciences of the United States of America. 2015. 112:E30–E38. doi: 10.1073/pnas.1421641112 PMID: 25535374
"... Many cellular functions depend on highly specific intermolecular interactions, for example transcription factors and their DNA binding sites, microRNAs and their RNA binding sites, the interfaces between heterodimeric protein molecules, the stems in RNA molecules, and kinases and their response reg ..."
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will be phrased in the context of the evolution of a transcription-factor binding site (TFBS) and its cognate transcription factor (TF). The general formulations can be equally applied to the complementary interfaces involving an untranslated region of an mRNA and a microRNA, the monomeric subunits of a dimeric

TRANSITION VITREUSE ET TRANSITION DE BLOCAGE:

by Blocage Les, Solides Désordonnés Entre, Romain Mari, Thèse De Doctorat, Romain Mari, M. Jean-louis, M. Ludovic, M. Viktor, Dotsenko Examinateur, M. Sylvio, Franz Examinateur, M. Gilles, Tarjus Examinateur, M. Jorge, Kurchan Directeur Thèse , 2011
"... HAL is a multi-disciplinary open access archive for the deposit and dissemination of sci-entific research documents, whether they are pub-lished or not. The documents may come from teaching and research institutions in France or abroad, or from public or private research centers. L’archive ouverte p ..."
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HAL is a multi-disciplinary open access archive for the deposit and dissemination of sci-entific research documents, whether they are pub-lished or not. The documents may come from teaching and research institutions in France or abroad, or from public or private research centers. L’archive ouverte

TRANSITION VITREUSE ET TRANSITION DE BLOCAGE: LES SOLIDES DÉSORDONNÉS ENTRE CHAMP MOYEN ET DIMENSION FINIE.

by De La Region Parisienne, Thèse De Doctorat, Romain Mari, Thèse Dirigée Par Jorge Kurchan, M. Jean-louis, M. Ludovic, M. Viktor, Dotsenko Examinateur, M. Sylvio, Franz Examinateur, M. Gilles, Tarjus Examinateur , 2011
"... Cette thèse est consacrée à l’étude de la transition liquide/solide amorphe. Cette transition se retrouve dans des systèmes thermiques (par exemple dans les verres moléculaires) ou athermiques (avec entre autres les milieux granulaires), à l’équilibre thermodynamique ou hors équilibre. Nous montrons ..."
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Cette thèse est consacrée à l’étude de la transition liquide/solide amorphe. Cette transition se retrouve dans des systèmes thermiques (par exemple dans les verres moléculaires) ou athermiques (avec entre autres les milieux granulaires), à l’équilibre thermodynamique ou hors équilibre. Nous
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