During the monitoring of pharmacoresistant epilepsy patients prior to surgery, interictal epileptic discharges (IEDs) are analyzed to locate possible sources of epileptic activity. In order to compen-sate low spatial resolution of EEG, simultaneous EEG-fMRI record-ings can be used. Conventional

using EEG-triggered fMRI

The General Linear Model (GLM), has been used to analyse simultaneous EEG-fMRI to reveal BOLD changes linked to interictal epileptic discharges (IED) identified on scalp EEG. This approach is ineffective when IED are not evident in the EEG. Data-driven fMRI analysis techniques that do not require

field. One way to explain this is to assume that multiple stimuli activate competing populations of neurons and that attention biases this competition in favor of the attended stimulus. In the absence of competing stimuli, there is no competition to be resolved. Accordingly, attention has a more limited

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apply PLS to investigate intracortical recordings from an epileptic patient performing a visual discrimination task. We find large-scale synchronies in the gamma band (45 Hz), e.g., between hippocampus and frontal gyrus, and local synchronies, within a limbic region, a few cm apart. We argue

Simultaneous intracranial EEG and fMRI of interictal epileptic discharges in humans

Abstract: A cerebral network comprising precuneus, medial frontal, and temporoparietal cortices is less active both during goal-directed behavior and states of reduced consciousness than during conscious rest. We tested the hypothesis that the interictal epileptic discharges affect activity

Abstract not found