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doi:10.1093/bioinformatics/btl437BIOINFORMATICS DISCOVERY NOTE Sequence analysis Significant sequence similarities in promoters and precursors of Arabidopsis thaliana non-conserved microRNAs
"... Some plant microRNAs have been shown to be de novo generated by inverted duplication from their target genes. Subsequent duplication events potentially generate multigene microRNA families. Within this article we provide supportive evidence for the inverted duplication model of plant microRNA evolut ..."
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evolution. First, we report that the pre-cursors of four Arabidopsis thaliana microRNA families, miR157, miR158, miR405 and miR447 share nearly identical nucleotide sequences throughout the whole miRNA precursor between the family members. The extent and degree of sequence conservation is suggestive
Arabidopsis thaliana non-conserved microRNAs
"... Significant sequence similarities in promoters and precursors of ..."
RESEARCH ARTICLE Open Access Functional and evolutionary analyses of the miR156 and miR529 families in land plants
"... Background: MicroRNAs (miRNAs) are important regulatory elements of gene expression. Similarly to coding genes, miRNA genes follow a birth and death pattern of evolution likely reflecting functional relevance and divergence. For instance, miRNA529 is evolutionarily related to miRNA156 (a highly cons ..."
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conserved miRNA in land plants), but it is lost in Arabidopsis thaliana. Interestingly, both miRNAs target sequences overlap in some members of the SQUAMOSA promoter-binding protein like (SPL) family, raising important questions regarding the diversification of the miR156/miR529-associated regulatory
