Imprinted genes are a subset of genes that are expressed from only one of the parental alleles. The majority of imprinted genes have roles in growth regulation and are, therefore, potential oncogenes or tumour suppressors. Cancer is a disease of aberrant cell growth and is characterised by genetic

of knowledge and a book in Her lotus hands. Dedicated to the Lotus Feet of the revered Sadguru. This thesis presents a new active mask (AM) framework and an algorithm for segmenta-tion of digital images, particularly those of punctate patterns from fluorescence microscopy. Fluorescence microscopy has greatly

a conserved role for IQGAP1 in protein synthesis and membrane traffic, which may help to explain the diversity of its cellular functions. Membrane traffic mediates infections by intracellular pathogens and a range of degenerative human diseases arise from dysfunctions in intracellular traffic; thus

understanding of the genetic factors underlying the ASDs. These approaches include whole-genome and pathway-based association studies, dense resequencing to identify Gene association studies a set of methods that is used to determine the correlation (positive or negative) between a defined genetic variant and a

diabetes from non-diabetes individuals. In this way, it was found that the patterns of IgG antibodies expressed early in male NOD mice can mark susceptibility or resistance to diabetes induced later and that it is different than the pattern characteristic of healthy or diabetic mice after disease induction