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EXTERMINATING THE CYBER FLEA: IRREGULAR WARFARE LESSONS FOR CYBER DEFENCE

by Ben Whitham
"... Traditional approaches to tactical Computer Network Defence (CND), drawn from the lessons and doctrine of conventional warfare, are based on a team of deployed security professionals countering the adversary’s cyber forces. The concept of the adversary in cyberspace does not fit neatly into the conv ..."
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best practices, intentional or otherwise, is the real adversary. This approach appears more likely to deliver long term protection from the current cyber threats than a process, which requires the identification and tracking of adversaries that are invisible and constantly changing.

Pietschmann T: Hepatitis C virus complete life cycle screen for identification of small molecules with pro- or antiviral activity

by Juliane Gentzsch , Bettina Hinkelmann , Lars Kaderali , Herbert Irschik , Rolf Jansen , Florenz Sasse , Ronald Frank , Thomas Pietschmann - Antiviral Res
"... a b s t r a c t Infection with the hepatitis C virus represents a global public health threat given that an estimated 170 million individuals are chronically infected and thus at risk for cirrhosis and hepatocellular carcinoma. A number of direct antiviral molecules are in clinical development. How ..."
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. However, side effects, drug resistance and viral genotype-specific differences in efficacy may limit these novel therapeutics. Therefore, a combination of well tolerated drugs with distinct mechanisms of action targeting different steps of the viral replication cycle will likely improve viral response

MiTAP for Bio-Security: A Case Study Global Tracking of Infectious Disease Outbreaks and Emerging Biological Threats

by Laurie Damianos , Jay Ponte , Steve Wohlever , Florence Reeder , David Day , George Wilson , Lynette Hirschman
"... Abstract * MiTAP (MITRE Text and Audio Processing) is a prototype system available for monitoring infectious disease outbreaks and other global events. MiTAP focuses on providing timely, multi-lingual, global information access to medical experts and individuals involved in humanitarian assistance ..."
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very real threat. On September 11 th , 2001, the Center for Disease Control alerted states and local public health agencies to monitor for any unusual disease patterns, including the effects of chemical and biological agents. In addition to possible disruption and loss of life, bioterrorism could

Identification of novel host-oriented targets for Human Immunodeficiency Virus type 1 using Random Homozygous Gene Perturbation

by Virology Journal, Hanwen Mao, Hanson Chen, Zena Fesseha, Shaojing Chang, Jessica Van Dyke, Manu Kohli, Wu-bo Li, Michael Goldblatt, Michael S Kinch, Michael Goldblatt, Michael S Kinch
"... Background: Human Immunodeficiency Virus (HIV) is a global threat to public health. Current therapies that directly target the virus often are rendered ineffective due to the emergence of drug-resistant viral variants. An emerging concept to combat drug resistance is the idea of targeting host mecha ..."
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Background: Human Immunodeficiency Virus (HIV) is a global threat to public health. Current therapies that directly target the virus often are rendered ineffective due to the emergence of drug-resistant viral variants. An emerging concept to combat drug resistance is the idea of targeting host

1 The Identification of Shared Major Histocompatibility Complex Class I Alleles in Domestic Ferrets

by unknown authors
"... The domestic ferret (Mustela putorius furo) is the most commonly used animal model for human influenza disease pathogenesis and vaccine development in humans. Influenza research is ongoing due to the threat of potential epidemics and pandemics emerging due to viral variants. Ferrets are the premier ..."
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The domestic ferret (Mustela putorius furo) is the most commonly used animal model for human influenza disease pathogenesis and vaccine development in humans. Influenza research is ongoing due to the threat of potential epidemics and pandemics emerging due to viral variants. Ferrets are the premier

The Body as a Source of Self-esteem: The Effect of Mortality Salience on Identification with One's Body, Interest in Sex and Appearance Monitoring

by Orit Ben-Ari , Victor Taubman , Mario Florian , ; Mikulincer , Ferraro , Baba Roselina , James R Shiv , Bettman , Jamie L Goldenberg , K Shannon , Tom Mccoy , Jeff Pyszczynski , Sheldon Greenberg , Solomon
"... Recurrent mortality salience may increase propensity for risky hedonic behaviors as has been observed under conditions of manipulated mortality salience. This recurrent mortality salience could be initiated by conditions of existence that lead to frequent reminders of fatalities associated with suc ..."
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living up to its values. When mortality salience occurs, individuals seek to defend their cultural worldview as well as to increase their self-esteem. An example of the former effect would be resistance to persuasion that carries messages counter to their worldview (Shehryar and Hunt, 2005) especially

A Novel Small Molecule Inhibitor of Influenza A Viruses that Targets Polymerase Function and Indirectly Induces

by Mila Brum Ortigoza, Oliver Dibben, Jad Maamary, Luis Martinez-gil, Victor H. Leyva-grado, Pablo Abreu, Juan Ayllon, Peter Palese, Megan L. Shaw
"... Influenza viruses continue to pose a major public health threat worldwide and options for antiviral therapy are limited by the emergence of drug-resistant virus strains. The antiviral cytokine, interferon (IFN) is an essential mediator of the innate immune response and influenza viruses, like many v ..."
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Influenza viruses continue to pose a major public health threat worldwide and options for antiviral therapy are limited by the emergence of drug-resistant virus strains. The antiviral cytokine, interferon (IFN) is an essential mediator of the innate immune response and influenza viruses, like many

METHODOLOGY ARTICLE A novel termini analysis th n

by unknown authors
"... Enterococcus faecalis and Enterococcus faecium are the most common enterococcal bacteria cultured from reliably effective against enterococci [12]. The continu-ous overuse and misuse of antibiotics has produced Zhang et al. BMC Genomics (2015) 16:414 DOI 10.1186/s12864-015-1612-3ation, and regulatio ..."
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Gram-positive pathogens, responsible for various diseases [2–8]. Recently, strains of enterococci resistant to vancomycin have emerged, with an increased incidence reported worldwide [9–11]. antibiotic-resistant Enterococcus. These, most notably vancomycin-resistant Enterococcus, have become a threat

The social roots of the partisan gender gap

by Barry C Burden - Public Opinion Quarterly , 2008
"... Abstract I suggest that the gender gap in party identification is partly an artifact of question wording and asymmetric stereotypes about men and women's partisan preferences. The Michigan model holds that party identification is fundamentally affective, yet surveys have always asked responden ..."
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. The paper proceeds as follows. I first briefly review the recent literature on the partisan gender gap. The review indicates that sex differences in party identification are due to such things as issue attitudes, views of the economy, and self-interest, though even these do not always account for the entire

Approved as to style and content by:

by Adam C. Polak, Prof Marco, F. Duarte, Prof Robert, W. Jackson, Prof Brian, N. Levine, Prof C. V. Hollot, Department Chair , 2014
"... This Open Access Dissertation is brought to you for free and open access by the Dissertations and Theses at ScholarWorks@UMass Amherst. It has ..."
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This Open Access Dissertation is brought to you for free and open access by the Dissertations and Theses at ScholarWorks@UMass Amherst. It has
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