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Tomography Bum Sang Cho, Kil Sun Park,
, 2011
"... This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License ..."
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This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License
They are: CHA Laura M (史美 倫), CHEN Lok Yee Laura (陳樂 怡), FANG Meng Sang Christine (方敏 生),
, 2009
"... Community Business would like to thank Standard Chartered Bank for their sponsorship of this first ..."
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Community Business would like to thank Standard Chartered Bank for their sponsorship of this first
Modulation of N-Type Ca 2ϩ Currents by A 1 -Adenosine Receptor Activation in Male Rat Pelvic Ganglion Neurons KYU-SANG PARK, SEONG-WOO JEONG, SEUNG-KYU CHA, BOO-SOO LEE, IN DEOK
"... ABSTRACT Modulation of voltage-activated Ca 2ϩ channels by adenosine was investigated in male rat major pelvic ganglion (MPG) neurons by using the whole-cell variant of the patch-clamp technique. Adenosine inhibited high voltage-activated (HVA) Ca 2ϩ currents in a concentration-dependent manner wit ..."
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ABSTRACT Modulation of voltage-activated Ca 2ϩ channels by adenosine was investigated in male rat major pelvic ganglion (MPG) neurons by using the whole-cell variant of the patch-clamp technique. Adenosine inhibited high voltage-activated (HVA) Ca 2ϩ currents in a concentration-dependent manner with an EC 50 of 313 nM and a maximal inhibition of 36%, respectively. Inhibition of HVA Ca 2ϩ currents in adrenergic and cholinergic MPG neurons was similar. Adenosine did not modulate T-type Ca 2ϩ channels present in adrenergic MPG neurons. Reverse transcription-polymerase chain reaction analysis indicated that MPG neurons express mRNAs encoding A 1 and A 2a receptors. Ca 2ϩ current inhibition by adenosine was mimicked by N 6 -cyclopentyladenosine, an A 1 -selective agonist (EC 50 ϭ 63 nM) and prevented by 100 nM 8-cyclopentyl-1,3-dipropylxanthine, an A 1 -selective antagonist. Conversely, CGS 21680, an A 2a -selective agonist, displayed a relatively low potency (EC 50 ϭ 2200 nM) for inhibiting Ca 2ϩ currents. The action of adenosine was significantly attenuated by 2 mM guanosine-5Ј-thiodiphosphate or 500 ng/ml pertussis toxin. The voltage dependence of adenosine-induced current inhibition was evident by 1) a bellshaped profile between the current inhibition and test potentials, 2) kinetic slowing in the presence of agonist, and 3) relief of the current inhibition by a conditioning prepulse to ϩ80 mV. Finally, 1 M -conotoxin GVIA occluded adenosine-induced current inhibition. Taken together, we concluded that adenosine inhibits N-type Ca 2ϩ currents by activation of A 1 receptors via a voltage-dependent and PTX-sensitive pathway in rat MPG neurons. Our data may explain how adenosine acts as an inhibitory modulator of ganglionic and neuromuscular transmission in the pelvic plexus.
RESEARCH Open Access Evaluation
"... of bone formation and membrane degradation in guided bone regeneration using a 4-hexylresorcinol-incorporated silk fabric membrane Sang-Woon Lee1*, In Chul Um2, Seong-Gon Kim3 and Min-Sang Cha1 Background: The aims of present study were (1) to evaluate new bone formation among the 4-hexylresorcinol ..."
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of bone formation and membrane degradation in guided bone regeneration using a 4-hexylresorcinol-incorporated silk fabric membrane Sang-Woon Lee1*, In Chul Um2, Seong-Gon Kim3 and Min-Sang Cha1 Background: The aims of present study were (1) to evaluate new bone formation among the 4-hexylresorcinol
Hysteresis Neural Networks for N-Queens Problems
, 1999
"... Introduction The optimizaSS' problemsao encountered in vaJ4`W situa4N3S There isa problem whichha discrete determined va'DWjN3 iscaWJJ "Combina'DDJN OptimizaN3S Problems." Usuale this problem iscomplicaSD more tha a linea progra`jN3S ar it iscaJDD "NP-HaN3J For this p ..."
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Cited by 2 (0 self)
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For this problems, vaWSqS aSqSWN3J' ha ve been proposed. As one of solvingavingNW4` Artificia Neura Network (aN ANN)ha been proposed [1]--[3]. ANN consists of ma y neurons whichaW nonlinea elements. BecaJ' ac neuron cells cha4` inpaW#jW`N ANN finds the solutioninsta tly. It isfa`J' tha D.W.TaW a J
Effective Simulation Frameworks for 3D Graphics Architectures and Acceleration Schemes for GPU-based Volume Visualization
, 2006
"... This dissertation would not have been possible without the help of many people. First of all, my most sincere thanks go to my research advisor, Professor Tack-Don Han, whose perceptive criticism, kind encouragement, and willing advice helped bring the PhD course to a successful conclusion. I would l ..."
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like to give particular thanks to my committee Professors, Sung-Bong Yang, In-Kwon Lee, Vason P. Srini (ICU, Dataflux Systems), and Woo-Chan Park (Sejong University) for their invaluable coments and suggestion. I wish to thank other Professors in Yonsei University, Shin-Dug Kim, HoJung Cha, Yong
COMMENTARY
"... Genetic control of mammalian T-cell proliferation with a synthetic RNA regulatory system- illusion or reality? Sang Kil Lee 1,2 and George A Calin 1 * Synthetic RNA-based regulatory systems are used to program higher-level biological functions that could be exploited, among many applications, for in ..."
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Genetic control of mammalian T-cell proliferation with a synthetic RNA regulatory system- illusion or reality? Sang Kil Lee 1,2 and George A Calin 1 * Synthetic RNA-based regulatory systems are used to program higher-level biological functions that could be exploited, among many applications
art 8 vol IV is 1
"... Qu ua al li it ta at ti iv ve e S So oc ci io ol lo og gy y R Re ev vi ie ew w V Vo ol lu um me e I IV V I Is ss su ue e 1 1 w ww ww w. .q qu ua al li it ta at ti iv ve es so oc ci io ol lo og gy yr re ev vi ie ew w. .o or rg g 1 15 50 0 Q Qu ua al li it ta at ti iv ve e S So oc ci io ol lo og gy y ..."
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y R Re ev vi ie ew w Volume IV, Issue 1 -April 2008 Sang-hui Nam German Institute of Global and Area Studies, Germany The Construction of Self-Identity in the Chronically Mentally Ill: A Focus on Autobiographic Narratives of Mentally Ill Patients in South Korea Abstract . A systematic policy
Die Deutsche Bibliothek- Cataloging in Publication Data
, 1996
"... @ Printed on acid-free paper which falls within the guidelines of the ANSI ..."
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@ Printed on acid-free paper which falls within the guidelines of the ANSI