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1 Projection OCT fundus imaging for visualizing outer retinal pathology in non- exudative age related macular

by Iwona Gorczynska, Vivek J. Srinivasan, Laurel N. Vuong, Royce W. S. Chen, Jonathan J. Liu, Elias Reichel, Maciej Wojtkowski, Joel S. Schuman, Jay S. Duker, James G. Fujimoto, James G. Fujimoto
"... degeneration ..."
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degeneration

Functional candidate genes in age-related macular degeneration: significant association with VEGF

by Jonathan L Haines , Nathalie Schnetz-Boutaud , Silke Schmidt , William K Scott , Anita Agarwal , Eric A Postel , Lana Olson , Shannon J Kenealy , Michael Hauser , John R Gilbert , Margaret A Pericak-Vance , Jonathan L Haines , 2006
"... PURPOSE. Age-related macular degeneration (AMD) is a retinal degenerative disease that is the leading cause of blindness worldwide for individuals over the age of 60. Although the etiology of AMD remains largely unknown, numerous studies have suggested that both genes and environmental risk factors ..."
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PURPOSE. Age-related macular degeneration (AMD) is a retinal degenerative disease that is the leading cause of blindness worldwide for individuals over the age of 60. Although the etiology of AMD remains largely unknown, numerous studies have suggested that both genes and environmental risk

Evaluating Potential Therapies in a Mouse Model of Focal Retinal Degeneration with Age-related Macular Degeneration

by Xi K. Chu, Defen Shen, Jingsheng Tuo, Chi-chao Chan
"... Although the mouse has no macula leutea, its neuroretina and retinal pigment epithelium (RPE) can develop lesions mimicking certain features of age-related macular degeneration (AMD). Differences between the Ccl2 and Cx3cr1 double deficient mouse on Crb1rd8(rd8) background (DKOrd8) and the Crb1rd8 m ..."
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Although the mouse has no macula leutea, its neuroretina and retinal pigment epithelium (RPE) can develop lesions mimicking certain features of age-related macular degeneration (AMD). Differences between the Ccl2 and Cx3cr1 double deficient mouse on Crb1rd8(rd8) background (DKOrd8) and the Crb1rd8

Functionally Guided Retinal Protective Therapy for Dry Age-Related Macular and Inherited Retinal Degenerations: A Pilot Study

by Jeffrey K Luttrull , Benjamin W L Margolis , 2016
"... Citation: Luttrull JK, Margolis BWL. Functionally guided retinal protective therapy for dry age-related macular and inherited retinal degenerations: a pilot study. Invest Ophthalmol Vis Sci. 2016;57:265-275. DOI:10.1167/ iovs.15-18163 PURPOSE. To review the results of retinal function testing ..."
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Citation: Luttrull JK, Margolis BWL. Functionally guided retinal protective therapy for dry age-related macular and inherited retinal degenerations: a pilot study. Invest Ophthalmol Vis Sci. 2016;57:265-275. DOI:10.1167/ iovs.15-18163 PURPOSE. To review the results of retinal function testing

Reticular Pseudodrusen in Early Age-Related Macular Degeneration Are Associated With Choroidal Thinning

by Aakriti Garg , Maris Oll , Suzanne Yzer , Stanley Chang , Gaetano R Barile , John C Merriam , Stephen H Tsang , Srilaxmi Bearelly , Srilaxmi Bearelly , 2013
"... PURPOSE. To compare choroidal thickness (CT) measurements in early AMD between patients with and without reticular pseudodrusen (RPD) using spectral-domain optical coherence tomography (SD-OCT). METHODS. This cross-sectional study examined 84 age-and sex-matched AMD patients (40 RPD [63 eyes], 44 n ..."
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to understanding RPD, and may be helpful in stratifying AMD progression risk. Keywords: reticular pseudodrusen, spectral-domain optical coherence tomography, choroidal layer, early age-related macular degeneration, retinal ischemia A ge-related macular degeneration is the leading cause of vision loss in developing

Age-Related Macular Degeneration and Long-Term Risk of Stroke Subtypes

by M. Kamran Ikram, David J. Couper, Phd Tien, Y. Wong
"... Background and Purpose—We examined the relationship of age-related macular degeneration (AMD) with incident stroke, including stroke subtypes of cerebral infarction and intracerebral hemorrhage. Methods—We included 12 216 participants with retinal photographs taken at the third examination visit (19 ..."
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of both cerebral infarction and intracerebral hemorrhage. These data provide further insight into common pathophysiological processes between AMD and stroke subtypes. (Stroke. 2012;43:1681-1683.) Key Words: age-related macular degeneration cerebral infarction intracerebral hemorrhage retinal imaging

Vitamin Usage Patterns in the Prevention of Advanced Age-Related Macular Degeneration

by Neil M. Bressler, Susan B. Bressler
"... Objective: To describe micronutrient usage patterns among patients at a tertiary ophthalmic center. Design: Cross-sectional clinical case series. Participants: Three hundred thirty-two adult patients with a diagnosis of age-related macular degeneration (AMD). Methods: Participants were surveyed abou ..."
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Objective: To describe micronutrient usage patterns among patients at a tertiary ophthalmic center. Design: Cross-sectional clinical case series. Participants: Three hundred thirty-two adult patients with a diagnosis of age-related macular degeneration (AMD). Methods: Participants were surveyed

Correlation of SD-OCT features and retinal sensitivity in neovascular age-related macular degeneration.

by Florian Sulzbacher , Christopher Kiss , Alexandra Kaider , Stefan Eisenkoelbl , Marion Munk , Philipp Roberts , Stefan Sacu , Ursula Schmidt-Erfurth - Invest Ophthalmol Vis Sci , 2012
"... PURPOSE. To correlate retinal sensitivity in patients with neovascular age-related macular degeneration (AMD) with specific characteristics of retinal morphology. METHODS. Thirty eyes of 30 patients presenting with active choroidal neovascularization were examined by spectral domain optical coheren ..."
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PURPOSE. To correlate retinal sensitivity in patients with neovascular age-related macular degeneration (AMD) with specific characteristics of retinal morphology. METHODS. Thirty eyes of 30 patients presenting with active choroidal neovascularization were examined by spectral domain optical

Evaluation of Optical Coherence Tomography Retinal Thickness Parameters for Use in Clinical Trials for Neovascular Age-Related Macular Degeneration

by Pearse A Keane , Sandra Liakopoulos , Renu V Jivrajka , Karen T Chang , Tarek Alasil , Alexander C Walsh , Srinivas R Sadda , 2009
"... PURPOSE. To investigate the relationship between automated and manually derived measurements of central retinal thickness from optical coherence tomography (OCT) and to determine the relationship between the foveal center point (FCP) and the foveal central subfield (FCS) in neovascular age-related ..."
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PURPOSE. To investigate the relationship between automated and manually derived measurements of central retinal thickness from optical coherence tomography (OCT) and to determine the relationship between the foveal center point (FCP) and the foveal central subfield (FCS) in neovascular age-related

In Vivo Three-Dimensional Imaging of Neovascular Age-Related Macular Degeneration Using Optical Frequency Domain Imaging at 1050 nm

by Daniel M De Bruin , Daina L Burnes , John Loewenstein , Yueli Chen , Susie Chang , Teresa C Chen , Daniel D Esmaili , Johannes F De Boer
"... PURPOSE. To assess the application of optical frequency domain imaging (OFDI) at 1050 nm for the detection of choroidal neovascularization (CNV) in age-related macular degeneration (AMD) and its response to treatment. Three patients presenting with blurred vision and exudative AMD were imaged befor ..."
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PURPOSE. To assess the application of optical frequency domain imaging (OFDI) at 1050 nm for the detection of choroidal neovascularization (CNV) in age-related macular degeneration (AMD) and its response to treatment. Three patients presenting with blurred vision and exudative AMD were imaged
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