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360,354
Rearrangement of DNA fragments: a branchandcut algorithm
, 1996
"... In this paper we consider a problem that arises in the process of reconstruction of DNA fragments. We present a graph theoretical formulation of the problem and mention some extensions. We show this problem to be NPhard. A 01 integer linear programming formulation of the problem is given and some ..."
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Cited by 7 (0 self)
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preliminary results of a branchandcut algorithm based on this formulation are discussed.
Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation
 J. Cell
, 1992
"... Abstract. Programmed cell death (PCD) plays a key role in developmental biology and in maintenance of the steady state in continuously renewing tissues. Currently, its existence is inferred mainly from gel electrophoresis of a pooled DNA extract as PCD was shown to be associated with DNA fragmentati ..."
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Cited by 656 (0 self)
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Abstract. Programmed cell death (PCD) plays a key role in developmental biology and in maintenance of the steady state in continuously renewing tissues. Currently, its existence is inferred mainly from gel electrophoresis of a pooled DNA extract as PCD was shown to be associated with DNA
Factor Graphs and the SumProduct Algorithm
 IEEE TRANSACTIONS ON INFORMATION THEORY
, 1998
"... A factor graph is a bipartite graph that expresses how a "global" function of many variables factors into a product of "local" functions. Factor graphs subsume many other graphical models including Bayesian networks, Markov random fields, and Tanner graphs. Following one simple c ..."
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Cited by 1787 (72 self)
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computational rule, the sumproduct algorithm operates in factor graphs to computeeither exactly or approximatelyvarious marginal functions by distributed messagepassing in the graph. A wide variety of algorithms developed in artificial intelligence, signal processing, and digital communications can
Tandem repeats finder: a program to analyze DNA sequences
, 1999
"... A tandem repeat in DNA is two or more contiguous, approximate copies of a pattern of nucleotides. Tandem repeats have been shown to cause human disease, may play a variety of regulatory and evolutionary roles and are important laboratory and analytic tools. Extensive knowledge about pattern size, co ..."
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Cited by 946 (9 self)
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A tandem repeat in DNA is two or more contiguous, approximate copies of a pattern of nucleotides. Tandem repeats have been shown to cause human disease, may play a variety of regulatory and evolutionary roles and are important laboratory and analytic tools. Extensive knowledge about pattern size
Fast Parallel Algorithms for ShortRange Molecular Dynamics
 JOURNAL OF COMPUTATIONAL PHYSICS
, 1995
"... Three parallel algorithms for classical molecular dynamics are presented. The first assigns each processor a fixed subset of atoms; the second assigns each a fixed subset of interatomic forces to compute; the third assigns each a fixed spatial region. The algorithms are suitable for molecular dyn ..."
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Cited by 622 (6 self)
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Three parallel algorithms for classical molecular dynamics are presented. The first assigns each processor a fixed subset of atoms; the second assigns each a fixed subset of interatomic forces to compute; the third assigns each a fixed spatial region. The algorithms are suitable for molecular
A Simple, Fast, and Accurate Algorithm to Estimate Large Phylogenies by Maximum Likelihood
, 2003
"... The increase in the number of large data sets and the complexity of current probabilistic sequence evolution models necessitates fast and reliable phylogeny reconstruction methods. We describe a new approach, based on the maximumlikelihood principle, which clearly satisfies these requirements. The ..."
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Cited by 2109 (30 self)
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. The core of this method is a simple hillclimbing algorithm that adjusts tree topology and branch lengths simultaneously. This algorithm starts from an initial tree built by a fast distancebased method and modifies this tree to improve its likelihood at each iteration. Due to this simultaneous adjustment
The Omega Test: a fast and practical integer programming algorithm for dependence analysis
 Communications of the ACM
, 1992
"... The Omega testi s ani nteger programmi ng algori thm that can determi ne whether a dependence exi sts between two array references, and i so, under what condi7: ns. Conventi nalwi[A m holds thati nteger programmiB techni:36 are far too expensi e to be used for dependence analysi6 except as a method ..."
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Cited by 521 (15 self)
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The Omega testi s ani nteger programmi ng algori thm that can determi ne whether a dependence exi sts between two array references, and i so, under what condi7: ns. Conventi nalwi[A m holds thati nteger programmiB techni:36 are far too expensi e to be used for dependence analysi6 except as a method
FastMap: A Fast Algorithm for Indexing, DataMining and Visualization of Traditional and Multimedia Datasets
, 1995
"... A very promising idea for fast searching in traditional and multimedia databases is to map objects into points in kd space, using k featureextraction functions, provided by a domain expert [25]. Thus, we can subsequently use highly finetuned spatial access methods (SAMs), to answer several types ..."
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Cited by 497 (23 self)
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domain expert to assess the similarity/distance of two objects. Given only the distance information though, it is not obvious how to map objects into points. This is exactly the topic of this paper. We describe a fast algorithm to map objects into points in some kdimensional space (k is user
Maximum Likelihood Phylogenetic Estimation from DNA Sequences with Variable Rates over Sites: Approximate Methods
 J. Mol. Evol
, 1994
"... Two approximate methods are proposed for maximum likelihood phylogenetic estimation, which allow variable rates of substitution across nucleotide sites. Three data sets with quite different characteristics were analyzed to examine empirically the performance of these methods. The first, called ..."
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Cited by 540 (28 self)
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Two approximate methods are proposed for maximum likelihood phylogenetic estimation, which allow variable rates of substitution across nucleotide sites. Three data sets with quite different characteristics were analyzed to examine empirically the performance of these methods. The first, called the "discrete gamma model," uses several categories of rates to approximate the gamma distribution, with equal probability for each category. The mean of each category is used to represent all the rates falling in the category. The performance of this method is found to be quite good, and four such categories appear to be sufficient to produce both an optimum, or nearoptimum fit by the model to the data, and also an acceptable approximation to the continuous dis tribution. The second method, called "fixedrates mod el," classifies sites into several classes according to their rates predicted assuming the star tree. Sites in different classes are then assumed to be evolving at these fixed rates when other tree topologies are evaluated.
Results 1  10
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