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59,676
Accurate whole human genome sequencing using reversible terminator chemistry. Nature 456: 53–59
, 2008
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Alternative isoform regulation in human tissue transcriptomes
- Nature
, 2008
"... Through alternative processing of pre-mRNAs, individual mammalian genes often produce multiple mRNA and protein isoforms that may have related, distinct or even opposing functions. Here we report an in-depth analysis of 15 diverse human tissue and cell line transcriptomes based on deep sequencing of ..."
Abstract
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Cited by 525 (4 self)
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of cDNA fragments, yielding a digital inventory of gene and mRNA isoform expression. Analysis of mappings of sequence reads to exon-exon junctions indicated that 92-94% of human genes undergo alternative splicing (AS), ∼86 % with a minor isoform frequency of 15% or more. Differences in isoform
Limma: linear models for microarray data
- Bioinformatics and Computational Biology Solutions using R and Bioconductor
, 2005
"... This free open-source software implements academic research by the authors and co-workers. If you use it, please support the project by citing the appropriate journal articles listed in Section 2.1.Contents ..."
Abstract
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Cited by 759 (13 self)
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This free open-source software implements academic research by the authors and co-workers. If you use it, please support the project by citing the appropriate journal articles listed in Section 2.1.Contents
Hierarchical Models of Object Recognition in Cortex
, 1999
"... The classical model of visual processing in cortex is a hierarchy of increasingly sophisticated representations, extending in a natural way the model of simple to complex cells of Hubel and Wiesel. Somewhat surprisingly, little quantitative modeling has been done in the last 15 years to explore th ..."
Abstract
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Cited by 817 (84 self)
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The classical model of visual processing in cortex is a hierarchy of increasingly sophisticated representations, extending in a natural way the model of simple to complex cells of Hubel and Wiesel. Somewhat surprisingly, little quantitative modeling has been done in the last 15 years to explore
Attitude-Behavior Relations: A Theoretical Analysis and
- Review of Empirical Research, Psychological Bulletin
, 1977
"... Research on the relation between attitude and behavior is examined in light of the correspondence between attitudinal and behavioral entities. Such entities are defined by their target, action, context, and time elements. A review of available empirical research supports the contention that strong a ..."
Abstract
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Cited by 473 (3 self)
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Research on the relation between attitude and behavior is examined in light of the correspondence between attitudinal and behavioral entities. Such entities are defined by their target, action, context, and time elements. A review of available empirical research supports the contention that strong
Community detection in graphs
, 2009
"... The modern science of networks has brought significant advances to our understanding of complex systems. One of the most relevant features of graphs representing real systems is community structure, or clustering, i. e. the organization of vertices in clusters, with many edges joining vertices of th ..."
Abstract
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Cited by 801 (1 self)
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The modern science of networks has brought significant advances to our understanding of complex systems. One of the most relevant features of graphs representing real systems is community structure, or clustering, i. e. the organization of vertices in clusters, with many edges joining vertices of the same cluster and comparatively few edges joining vertices of different clusters. Such
The Landscape of Parallel Computing Research: A View from Berkeley
- TECHNICAL REPORT, UC BERKELEY
, 2006
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Nanotoxicology: an emerging discipline evolving from studies of ultrafine particles. Environ Health Perspect 113:823–839
, 2005
"... Although humans have been exposed to airborne nanosized particles (NSPs; < 100 nm) throughout their evolutionary stages, such exposure has increased dramatically over the last century due to anthropogenic sources. The rapidly developing field of nanotechnology is likely to become yet another sour ..."
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Cited by 430 (3 self)
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, and heart. Access to the central nervous system and ganglia via translocation along axons and dendrites of neurons has also been observed. NSPs penetrating the skin distribute via uptake into lymphatic channels. Endocytosis and biokinetics are
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