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206,718
Making LargeScale Support Vector Machine Learning Practical
, 1998
"... Training a support vector machine (SVM) leads to a quadratic optimization problem with bound constraints and one linear equality constraint. Despite the fact that this type of problem is well understood, there are many issues to be considered in designing an SVM learner. In particular, for large lea ..."
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Cited by 620 (1 self)
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Training a support vector machine (SVM) leads to a quadratic optimization problem with bound constraints and one linear equality constraint. Despite the fact that this type of problem is well understood, there are many issues to be considered in designing an SVM learner. In particular, for large
Sparse Bayesian Learning and the Relevance Vector Machine
, 2001
"... This paper introduces a general Bayesian framework for obtaining sparse solutions to regression and classication tasks utilising models linear in the parameters. Although this framework is fully general, we illustrate our approach with a particular specialisation that we denote the `relevance vec ..."
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Cited by 958 (5 self)
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vector machine' (RVM), a model of identical functional form to the popular and stateoftheart `support vector machine' (SVM). We demonstrate that by exploiting a probabilistic Bayesian learning framework, we can derive accurate prediction models which typically utilise dramatically fewer
Support Vector Machine Classification and Validation of Cancer Tissue Samples Using Microarray Expression Data
, 2000
"... Motivation: DNA microarray experiments generating thousands of gene expression measurements, are being used to gather information from tissue and cell samples regarding gene expression differences that will be useful in diagnosing disease. We have developed a new method to analyse this kind of data ..."
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Cited by 566 (1 self)
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using support vector machines (SVMs). This analysis consists of both classification of the tissue samples, and an exploration of the data for mislabeled or questionable tissue results. Results: We demonstrate the method in detail on samples consisting of ovarian cancer tissues, normal ovarian tissues
Support vector machine active learning for image retrieval
, 2001
"... Relevance feedback is often a critical component when designing image databases. With these databases it is difficult to specify queries directly and explicitly. Relevance feedback interactively determinines a user’s desired output or query concept by asking the user whether certain proposed images ..."
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Cited by 448 (29 self)
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are relevant or not. For a relevance feedback algorithm to be effective, it must grasp a user’s query concept accurately and quickly, while also only asking the user to label a small number of images. We propose the use of a support vector machine active learning algorithm for conducting effective relevance
Alternative isoform regulation in human tissue transcriptomes
 Nature
, 2008
"... Through alternative processing of premRNAs, individual mammalian genes often produce multiple mRNA and protein isoforms that may have related, distinct or even opposing functions. Here we report an indepth analysis of 15 diverse human tissue and cell line transcriptomes based on deep sequencing of ..."
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Cited by 525 (4 self)
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of cDNA fragments, yielding a digital inventory of gene and mRNA isoform expression. Analysis of mappings of sequence reads to exonexon junctions indicated that 9294% of human genes undergo alternative splicing (AS), ∼86 % with a minor isoform frequency of 15% or more. Differences in isoform
New Support Vector Algorithms
, 2000
"... this article with the regression case. To explain this, we will introduce a suitable definition of a margin that is maximized in both cases ..."
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Cited by 461 (42 self)
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this article with the regression case. To explain this, we will introduce a suitable definition of a margin that is maximized in both cases
Gaussian processes for machine learning
 in: Adaptive Computation and Machine Learning
, 2006
"... Abstract. We give a basic introduction to Gaussian Process regression models. We focus on understanding the role of the stochastic process and how it is used to define a distribution over functions. We present the simple equations for incorporating training data and examine how to learn the hyperpar ..."
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Cited by 631 (2 self)
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of statistics and machine learning, either for analysis of data sets, or as a subgoal of a more complex problem. Traditionally parametric 1 models have been used for this purpose. These have a possible advantage in ease of interpretability, but for complex data sets, simple parametric models may lack expressive
Sketchpad: A manmachine graphical communication system
, 2003
"... The Sketchpad system uses drawing as a novel communication medium for a computer. The system contains input, output, and computation programs which enable it to interpret information drawn directly on a computer display. It has been used to draw electrical, mechanical, scientific, mathematical, and ..."
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Cited by 702 (6 self)
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The Sketchpad system uses drawing as a novel communication medium for a computer. The system contains input, output, and computation programs which enable it to interpret information drawn directly on a computer display. It has been used to draw electrical, mechanical, scientific, mathematical
Software pipelining: An effective scheduling technique for VLIW machines
, 1988
"... This paper shows that software pipelining is an effective and viable scheduling technique for VLIW processors. In software pipelining, iterations of a loop in the source program are continuously initiated at constant intervals, before the preceding iterations complete. The advantage of software pipe ..."
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Cited by 579 (3 self)
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pipelining is that optimal performance can be achieved with compact object code. This paper extends previous results of software pipelining in two ways: First, this paper shows that by using an improved algorithm, nearoptimal performance can be obtained without specialized hardware. Second, we propose a
Greedy Function Approximation: A Gradient Boosting Machine
 Annals of Statistics
, 2000
"... Function approximation is viewed from the perspective of numerical optimization in function space, rather than parameter space. A connection is made between stagewise additive expansions and steepest{descent minimization. A general gradient{descent \boosting" paradigm is developed for additi ..."
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Cited by 951 (12 self)
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Function approximation is viewed from the perspective of numerical optimization in function space, rather than parameter space. A connection is made between stagewise additive expansions and steepest{descent minimization. A general gradient{descent \boosting" paradigm is developed for additive expansions based on any tting criterion. Specic algorithms are presented for least{squares, least{absolute{deviation, and Huber{M loss functions for regression, and multi{class logistic likelihood for classication. Special enhancements are derived for the particular case where the individual additive components are regression trees, and tools for interpreting such \TreeBoost" models are presented. Gradient boosting of regression trees produces competitive, highly robust, interpretable procedures for both regression and classication, especially appropriate for mining less than clean data. Connections between this approach and the boosting methods of Freund and Shapire 1996, and Frie...
Results 1  10
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206,718